News in Aging, Aging Services, and Aging-Related Disease
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News from Penn Medicine Research:
- Dismantling Alzheimer’s Disease: Penn Researchers Discover How Small Molecule Can Take Apart Disease-Associated Protein Fibers
- More Genes for Lou Gehrig’s Disease Identified, According to Penn Researchers
- Penn Researchers Find Increase in Disability Among Older, Obese Adults -- Dawn Alley, PhD, IOA Fellow and Robert Wood Johnson Health and Society Scholar
- New MRI Image Technique Predicts Early Onset of Alzheimer’s Disease in Patients with Mild Memory Problems
News Articles and Reports:
- New vaccine against Alzheimer's shows promise in monkeys -- The Dana Foundation
- Gentlemen, 5 Easy Steps to Living Long and Well -- nytimes.com
- Emotional Toll of Alzheimer's on the Spouse -- cnn.com
- Caring for Mom and Dad from Afar -- cnn.com
- "Goal driven achievers less prone to Alzheimer's", cnn.com
- "Grassroots Effort to Grow Old at Home", New York Times
- "Probing a Mind for a Cure: Shedding Light on a Fading Mind" - Philadelphia Inquirer, February 26, 2006
As dementia began to steal his brain, Bob Moore decided that eventually he wanted science to have it. His gift and others' are helping shed light on a disease that touches millions. Stories, slideshows on Robert Moore, and links to resources on Alzheimer's disease. - Huge Global Increase in Alzheimer's, Dementia Predicted, New York Times Syndicate
Articles and Papers on Aging, Aging Services and Aging-Related Disease (PDF format):
- Study finds improved cognitive health among older Americans -- National Institute on Aging
- "Physical Activity and Cognitive Health," Alzheimer’s & Dementia 3 (2007) 98-108, M. Kathryn Jedrziewski, Virginia M.-Y. Lee, and John Q. Trojanowski
- Healthy Ageing: A Challenge for Europe
- Stop and Go: Proteins Important in Alzheimer’s, Parkinson’s Disease Travel in the Slow Lane
- Targeting Tau - Penn researchers and colleagues gain more insight into Alzheimer's disease
- Alzheimer's Disease Clinical Trials and the Logic of Clinical Purpose, New England Journal of Medicine, October 12, editorial by Dr. Jason Karlawish
- Picking Apart the Causes of Mysterious Dementias, Science, October 6, 2006 Vol 314
- Mechanisms of Parkinson's Disease Linked to Pathological beta-Synuclein: New Targets for Drug Discovery, Neuron, Vol 52:33-38, October 5, 2006, Virginia M.-Y. Lee and John Q. Trojanowski
- Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis, Science, October 6, 2006, Vol 314:130-133, Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong, Adam C. Truax, Matthew C. Micsenyi, Thomas T. Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M. Clark, Leo F. McCluskey, Bruce L. Miller, Eliezer Masliah, Ian R. Mackenzie, Howard Feldman, Wolfgang Feiden, Hans A. Kretzschmar, John Q. Trojanowski, and Virginia M.-Y. Lee
- Humidity implicated in heart attack risk for older patients
Heart, July 12 - Activity found to spur prolonged life
Journal of the American Medical Association, July 12 - Thyroid Status, Cardiovascular Risk, and Mortality in Older Adults
Anne R. Cappola (IOA Fellow); Linda P. Fried; Alice M. Arnold; Mark D. Danese; Lewis H. Kuller; Gregory L. Burke; Russell P. Tracy; Paul W. Ladenson
JAMA. 2006;295:1033-1041. - (ASA) American Stroke Association: Guidelines Urge Same Urgency for TIAs as Stroke
- NIH Seeks Strategies to Preserve Brain Health
The Cognitive and Emotional Health Project’s searchable database of a large number of studies on age and cognitive and emotional function can be found on the NIH website at http://trans.nih.gov/CEHP. - Exercise and Heart Health May Keep Dementia at Arm's Length
- "Mortality after the Hospitalization of a Spouse"
Nicholas A. Christakis, MD, PhD, MPH, Harvard University and Paul D. Allison, PhD, University of Pennsylvania
New England Journal of Medicine Volume 354:719-730. February 16, 2006 - "Developing a Research Agenda in Biogerontology: Basic Mechanisms" Sage KE article (Science of Aging Knowledge Environment)
- "Are Baby Boomers Ready for Retirement? Housing and Financial Security for Leading Edge Boomers" -- A report commissioned by the Coalition for Research on Baby Boomer Housing and Retirement Options Housing & Financial Security for Leading Edge Boomers.
- "Appropriate Use of Artificial Nutrition and Hydration —
Fundamental Principles and Recommendations"
David Casarett, MD, Jennifer Kapo, MD, and Arthur Caplan, PhD (IOA Fellows)
New England Journal of Medicine 353;24. December 15, 2005. - Study: Scientists Focusing Less on Longevity, More on How We Age and Why We Die, new report prepared by Public Agenda for the Alliance for Aging Research and the American Federation for Aging Research.
- Imaging Study Links Key Genetic Risk Factor for Alzheimer Disease to Breakdown of Myelin Insulation Coating Brain Cell Connections - UCLA
- "Midlife Body Mass Index and Hospitalization and Mortality in Older Age" - Journal of the American Medical Association (JAMA)
- "Lowering the risk of Alzheimer's disease: Evidence-based practices emerge from new research" - M. Kathryn Jedrziewski, Virginia M.-Y. Lee, John Q. Trojanowski, Alzheimer's & Dementia 1 (2005) 152-160
- "Exercise Fends Off Dementia in Older Adults" - Annals of Internal Medicine Vol 144:2 (17 January 2006) 73-81
- "Hospitalization or Death of Elderly Spouse Substantially Affects Husband or Wife's Mortality" Link to full article in New England Journal of Medicine (February 16, 2007)
External Events and Conferences on Aging, Aging Services, and Aging-Related Diseases:
- Alzheimer: 100 Years and Beyond. Tubingen, Germany, November 2-5, 2006
Video streaming of conference - White House Conference on Aging 2005
For more information on the 2005 White House Conference on Aging, visit http://www.whcoa.gov/. - World Congress for Freedom of Scientific Research
Declaration of the First Meeting of the World Congress for Freedom of Scientific Research, Campidoglio, Rome 16 - 18 February 2007. (Webcasts of the Congress and meetings available.)
Click here for "Helpful Links for More Information on Aging and Aging Services - Local, State and National Levels"
Click here for Publications and Pamphlets available free, to the public.
Online Resources for Additional Information:
- NIHSeniorHealth
- PubMed (Medical articles, papers, abstracts)
- MedLine Plus (from the National Library of Medicine)
- Alzheimer's Disease page
- Dementia page
- International Health page
- MedPage Today (news in medicine, research, and prevention)