Table 2: Potential Members of the Aldo-Keto Reductase Superfamily
as of November 9, 2007
This table lists potential AKR superfamily members. These are currently excluded from the nomenclature because either no functional data exists for the protein or the sequence is a partial cDNA or derived from a genomics project.
| Species | Name | Accession | Ref: |
|---|---|---|---|
| Aeropyrum pernix | APE1495 APE1659 APE1961 |
7516538 7447932 7431108 |
|
| Agrobacterium tumefaciens | mocA | AAB07785 | |
| Aquifex aeolicus | aq323 | 7517567 | |
| Arabidopsis thaliana | aldehyde reductase homolog aldehyde reductase homolog putative reductase alcohol dehydrogenase mannose-6-phosphate reductase reductase-like protein reductase-like protein reductase-like protein reductase-like protein similar to auxin-induced protein similar to auxin-induced protein similar to auxin-induced protein reductase-like protein reductase-like protein hypothetical protein hypothetical protein hypothetical protein hypothetical protein |
F13M227 F13M226 AAD23673 AAD32792 AAD23674 CAB88350 CAB82283 AAD3933 AAD39334 AAB71980 AAF17106 AAB71981 AAB80621 AAD31332 AAB71969 AAB71960 7447943 AAC73032 |
116 |
| Babesia bovis | reductase | P40690 | 117 |
| Bacillus subtilis | yvgN ytbE yccK yrpG yqkF ycsN OrfC |
7431103 7431102 3183577 7447929 P54569 P42972 AAB53024 |
118-122 |
| Borrelia burgdorferi | ADR | G70165 | 123 |
| Caenorhabditis elegans | Y39G8Ba Y39G8B1b Y39G8B2 PF00248 C35D10.6 C01G5.5 K07C5.2 F37C12.12 C07D8.6 ZC443.1 F53F1.2 F53F1.3 |
7509715 6425257 CAB60336 AAA97992 2146873 7495133 7505423 7500712 7495605 7510761 7504052 7504053 |
124 |
| Cenarchaeum symbiosum | unknown unknown |
AAC62717 AAC62695 |
|
| Deinococcus radiodurans | probable oxidoreductase probable potassium channel probable oxidoreductase probable oxidoreductase |
7471099 7473637 7473601 7473607 |
|
| Drosophila melanogaster | CG6084 CG12766 CG10638 CG9436 CG2767 CG6083 CG18547 CG3397 |
AAF50039 AAF47812 AAF49912 AAF57392 AAF54175 AAF50038 AAF54729 AAF54731 |
|
| Escherichia coli | YQHE b3012 yafB yajO b1781 morphine-6-dehydrogenase ydjG b3001 ydbC ydhF |
Q46857 7431105 7427662 7447925 7427664 BAA15578 P77256 7447924 P25906 P76187 |
125 126 |
| Fragaria x ananassa | unknown | AAB97005 | 127 |
| Helianthus annuus | auxin-induced protein | AAB84222 | |
| Homo sapiens | aflatoxin B1 aldehyde reductase 3 | NP_957704 | |
| Hydrangea macrophylla | reductase (potential AKR4B member) reductase (potential AKR4B member) |
AAR89810 AAR89811 |
|
| Methanobacterium thermoautotrophicum | mth907 | 7482275 | |
| Mycobacterium leprae | reductase reductase |
2193903 3150217 |
128 |
| Mycobacterium tuberculosis | protein YM98 |
7431131 Q50668 |
129 |
| Neurospora crassa | YPR1 unknown |
CAB91236 7635782 |
|
| Nicotiana tabacum | auxin-induced protein | P40691 | |
| Oryza sativa | potassium channel | 7447935 | |
| Pseudomonas sp. | threo-aldose-1-dehydrogenase (EC 1.1.1.122) | JC2405 | 130 |
| Pyrococcus abyssi | morphine dehygrogenase | 7431107 | |
| Pyrococcus horikoshii | morphine dehydrogenase | 7431110 | 131 |
| Saccharomyces cerevisiae | ORF1 AAD6 Yd1124wp Yp1088wp Ypr127wp Ymr041cp Yjr096wp |
AAA35037 P43547 NP_010159 NP_015237 NP_015452 NP_013755 NP_012630 |
132-134 |
| Schizosaccharomyces pombe | ydg7 probable reductase probable K+ channel probable reductase probable reductase probable reductase probable reductase probable reductase probable reductase |
Q10494 T38538 7492838 CAB69636 7492371 7492786 BAA12182 7492370 7447931 |
|
| Solanum tuberosum | unknown | 7447934 | |
| Streptomyces clavuligerus | probable reductase | AAD30468 | |
| Streptomyces coelicolor | possible oxidoreductase possible oxidoreductase hypothetical protein SCH5 possible oxidoreductase possible oxidoreductase possible oxidoreductase possible oxidoreductase possible oxidoreductase possible oxidoreductase possible oxidoreductase probable ion channel possible oxidoreductase possible oxidoreductase |
7481096 7481111 7479621 CAB89759 CAB55711 CAB76089 CAB55656 CAB76977 7481102 CAB56659 7480891 CAB62709 CAB72221 |
|
| Synechocystis sp. | hypothetical protein hypothetical protein hypothetical protein hypothetical protein hypothetical protein |
7427663 7470456 7447939 7447940 7469950 |
|
| Thermotoga maritima | oxidoreductase oxidoreductase oxidoreductase oxidoreductase potassium channel oxidoreductase |
7431104 7462913 7431109 7447923 7447936 7462822 |
|
| Zea mays | auxin-induced protein IP2 | P49249 | |
| Zymomonas mobilis | morphine dehydrogenase | AAD19420 |