Table 2: Potential Members of the Aldo-Keto Reductase Superfamily
as of November 9, 2007

This table lists potential AKR superfamily members. These are currently excluded from the nomenclature because either no functional data exists for the protein or the sequence is a partial cDNA or derived from a genomics project.

Species Name Accession Ref:
Aeropyrum pernix APE1495
APE1659
APE1961
7516538
7447932
7431108
 
Agrobacterium tumefaciens mocA AAB07785  
Aquifex aeolicus aq323 7517567  
Arabidopsis thaliana aldehyde reductase homolog
aldehyde reductase homolog
putative reductase
alcohol dehydrogenase
mannose-6-phosphate reductase
reductase-like protein
reductase-like protein
reductase-like protein
reductase-like protein
similar to auxin-induced protein
similar to auxin-induced protein
similar to auxin-induced protein
reductase-like protein
reductase-like protein
hypothetical protein
hypothetical protein
hypothetical protein
hypothetical protein
F13M227
F13M226
AAD23673
AAD32792
AAD23674
CAB88350
CAB82283
AAD3933
AAD39334
AAB71980
AAF17106
AAB71981
AAB80621
AAD31332
AAB71969
AAB71960
7447943
AAC73032
116
Babesia bovis reductase P40690 117
Bacillus subtilis yvgN
ytbE
yccK
yrpG
yqkF
ycsN
OrfC
7431103
7431102
3183577
7447929
P54569
P42972
AAB53024
118-122
Borrelia burgdorferi ADR G70165 123
Caenorhabditis elegans Y39G8Ba
Y39G8B1b
Y39G8B2
PF00248
C35D10.6
C01G5.5
K07C5.2
F37C12.12
C07D8.6
ZC443.1
F53F1.2
F53F1.3
7509715
6425257
CAB60336
AAA97992
2146873
7495133
7505423
7500712
7495605
7510761
7504052
7504053
124
Cenarchaeum symbiosum unknown
unknown
AAC62717
AAC62695
 
Deinococcus radiodurans probable oxidoreductase
probable potassium channel
probable oxidoreductase
probable oxidoreductase
7471099
7473637
7473601
7473607
 
Drosophila melanogaster CG6084
CG12766
CG10638
CG9436
CG2767
CG6083
CG18547
CG3397
AAF50039
AAF47812
AAF49912
AAF57392
AAF54175
AAF50038
AAF54729
AAF54731
 
Escherichia coli YQHE
b3012
yafB
yajO
b1781
morphine-6-dehydrogenase
ydjG
b3001
ydbC
ydhF
Q46857
7431105
7427662
7447925
7427664
BAA15578
P77256
7447924
P25906
P76187
125 126
Fragaria x ananassa unknown AAB97005 127
Helianthus annuus auxin-induced protein AAB84222  
Homo sapiens aflatoxin B1 aldehyde reductase 3 NP_957704  
Hydrangea macrophylla reductase (potential AKR4B member)
reductase (potential AKR4B member)
AAR89810
AAR89811
 
Methanobacterium thermoautotrophicum mth907 7482275  
Mycobacterium leprae reductase
reductase
2193903
3150217
128
Mycobacterium tuberculosis protein
YM98
7431131
Q50668
129
Neurospora crassa YPR1
unknown
CAB91236
7635782
 
Nicotiana tabacum auxin-induced protein P40691  
Oryza sativa potassium channel 7447935  
Pseudomonas sp. threo-aldose-1-dehydrogenase (EC 1.1.1.122) JC2405 130
Pyrococcus abyssi morphine dehygrogenase 7431107  
 
Pyrococcus horikoshii morphine dehydrogenase 7431110 131
Saccharomyces cerevisiae ORF1
AAD6
Yd1124wp
Yp1088wp
Ypr127wp
Ymr041cp
Yjr096wp
AAA35037
P43547
NP_010159
NP_015237
NP_015452
NP_013755
NP_012630
132-134
Schizosaccharomyces pombe ydg7
probable reductase
probable K+ channel
probable reductase
probable reductase
probable reductase
probable reductase
probable reductase
probable reductase
Q10494
T38538
7492838
CAB69636
7492371
7492786
BAA12182
7492370
7447931
 
Solanum tuberosum unknown 7447934  
Streptomyces clavuligerus probable reductase AAD30468  
Streptomyces coelicolor possible oxidoreductase
possible oxidoreductase
hypothetical protein SCH5
possible oxidoreductase
possible oxidoreductase
possible oxidoreductase
possible oxidoreductase
possible oxidoreductase
possible oxidoreductase
possible oxidoreductase
probable ion channel
possible oxidoreductase
possible oxidoreductase
7481096
7481111
7479621
CAB89759
CAB55711
CAB76089
CAB55656
CAB76977
7481102
CAB56659
7480891
CAB62709
CAB72221
 
Synechocystis sp. hypothetical protein
hypothetical protein
hypothetical protein
hypothetical protein
hypothetical protein
7427663
7470456
7447939
7447940
7469950
 
Thermotoga maritima oxidoreductase
oxidoreductase
oxidoreductase
oxidoreductase
potassium channel
oxidoreductase
7431104
7462913
7431109
7447923
7447936
7462822
 
Zea mays auxin-induced protein IP2 P49249  
Zymomonas mobilis morphine dehydrogenase AAD19420  
* - Where no reference is given please refer to the accession number in the appropriate database.