Masahiro Iwamoto, Ph.D., D.D.S.
Masahiro Iwamoto, Ph.D., D.D.S.
Research Associate Professor of Orthopaedic Surgery
Department: Orthopaedic Surgery
Contact information
The Children's Hospital of Philadelphia
Translational Research Program in Pediatric Orthopaedics
Division of Orthopaedic Surgery
Department of Surgery
3615 Civic Center Boulevard
Abramson Research Center 910A
Philadelphia, PA 19104
Translational Research Program in Pediatric Orthopaedics
Division of Orthopaedic Surgery
Department of Surgery
3615 Civic Center Boulevard
Abramson Research Center 910A
Philadelphia, PA 19104
Office: 267-425-2072
Fax: 267-426-2215
Fax: 267-426-2215
Email:
iwamotom@email.chop.edu
iwamotom@email.chop.edu
Publications
Education:
D.D.S (Dental School)
Tokushima, 1984.
Ph.D (Dentistry)
Osaka University, 1988.
Permanent linkD.D.S (Dental School)
Tokushima, 1984.
Ph.D (Dentistry)
Osaka University, 1988.
Description of Research Expertise
Developmental biology of bone and cartilage.Tissue degeneration of skeletal tissue and muscle.
Microsurgery of small animals.
Selected Publications
Leslie Cantley, Cheri Saunders, Marta Guttenberg, Maria Elena Candela, Yoichi Ohta, Rika Yasuhara, Naoki Kondo, Federica Sgariglia, Shuji Asai, Julianne Hugel, Xianrong Zhang, Ling Qin, Jacqueline T. Hecht, Di Chen, Masato Yamamoto, Satoru Toyosawa, John Paul Dormans, Jeffrey D. Esko, Yu Yamaguchi, Masahiro Iwamoto, Maurizio Pacifici, Motomi Enomoto-Iwamoto: Loss of β-Catenin Induces Multifocal Periosteal Chondroma-like Masses in Mice. American Journal of Pathology 2013 Notes: Manuscript#AJP12-0453 Version 2: accepted for publication.Otsuru S, Gordon PL, Shimono K, Jethva R, Marino R, Phillips CL, Hofmann TJ, Veronesi E, Dominici M, Iwamoto M, Horwitz EM.: Transplanted bone marrow mononuclear cells and MSCs impart clinical benefit to children with osteogenesis imperfecta through different mechanisms. Blood 120(9): 1933-41, Aug 2012.
Honami T, Shimo T, Okui T, Kurio N, Hassan NM, Iwamoto M, Sasaki A.: Sonic hedgehog signaling promotes growth of oral squamous cell carcinoma cells associated with bone destruction. Oral Oncol. 48(1): 49-55, Jan 2012.
M. Enomoto-Iwamoto, C. Sunders, Y. Ohta, M. Guttenberg, R. Yasuhara, K. Shimono, N. Kondo, S. Asai, J. Hecht, S. Mackem, D. Chen, J. P. Dormans, M. Iwamoto, M. Pacifici : Loss of β-Catenin Induces Multifocal Ectopic Chondroma-like Masses in Adult Mice. Transactions/ Orthopaedic Research Society 37: 0265, 2012 Notes: 58th Annual Meeting of the Orthopaedic Research Society.
Y. Ohta, T. Okabe, S. Asai, A. Di Rocco, C. Larmour, M. Enomoto-Iwamoto, M. Pacifici, M. Iwamoto: Transcription Factor Erg Is Required for Long-term Articular Cartilage Maintenance. Transactions/ Orthopaedic Research Society 37: 341, 2012 Notes: 58th Annual Meeting of the Orthopaedic Research Society.
S. Asai, K. Shimono, W. Tung, M. Pacifici, M. Iwamoto, M. Enomoto-Iwamoto: Progenitors Recruited to Injured Tendons Are Possible Culprits of Chondroid Degeneration. Transactions/ Orthopaedic Research Society 37: 141, 2012 Notes: 58th Annual Meeting of the Orthopaedic Research Society.
Yasuhara Rika, Ohta Yoichi, Yuasa Takahito, Kondo Naoki, Hoang Tai, Addya Sankar, Fortina Paolo, Pacifici Maurizio, Iwamoto Masahiro, Enomoto-Iwamoto Motomi: Roles of β-catenin signaling in phenotypic expression and proliferation of articular cartilage superficial zone cells. Laboratory investigation; a journal of technical methods and pathology Oct 2011.
Honami Tatsuki, Shimo Tsuyoshi, Okui Tatsuo, Kurio Naito, Hassan Nur Mohammad Monsur, Iwamoto Masahiro, Sasaki Akira: Sonic hedgehog signaling promotes growth of oral squamous cell carcinoma cells associated with bone destruction. Oral oncology Sep 2011.
Shimono, K., Tung, W. E., Macolino, C., Chi, A. H., Didizian, J. H., Mundy, C., Chandraratna, R. A., Mishina, Y., Enomoto-Iwamoto, M., Pacifici, M., Iwamoto, M.: Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-gamma agonists. Nat Med 17(4): 454-60, 2011.
Mundy, C., Yasuda, T., Kinumatsu, T., Yamaguchi, Y., Iwamoto, M., Enomoto-Iwamoto, M., Koyama, E., Pacifici, M.: Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol 351(1): 70-81, 2011.