Peter S. White
Research Associate Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations
Contact information
CHOP
34th & CIVIC CENTER
Philadelphia, PA 19104-4399
34th & CIVIC CENTER
Philadelphia, PA 19104-4399
Office: 215-590-5241
Fax: 215-590-3020
Fax: 215-590-3020
Email:
white@genome.chop.edu
white@genome.chop.edu
Publications
Links
Search PubMed for articles
eGenome research webpage.
Center for Biomedical Informatics website
Search PubMed for articles
eGenome research webpage.
Center for Biomedical Informatics website
Education:
B.S. (Biology)
University of Oregon, 1986.
Ph.D. (Molecular Genetics)
Washington University, 1992.
Permanent linkB.S. (Biology)
University of Oregon, 1986.
Ph.D. (Molecular Genetics)
Washington University, 1992.
Description of Research Expertise
Dr. White oversees informatics research and resources at The Children's Hospital of Philadelphia, including genome-enabled medicine, clinical informatics, software development, educational, and bioinformatics activities. In addition, he has an active laboratory that is developing genomic analysis, natural language processing, data integration, and knowledge representation methods to help determine the molecular etiologies of particular pediatric diseases. Disorders of current interest include childhood cancer, diseases identified by newborn screening, and congenital cardiac defects. Dr. White plays a lead informatics role on a number of national data projects, including the NICHD Newborn Screening Translational Research Network, the NHLBI Bench to Bassinet Program, the NHGRI Clinical Sequencing and Exploratory Research Consortium, and the NIDCD Audiology and Genetics Database.Selected Publications
Gai X, Xie H M, Perin J C, Takahashi N, Murphy K, Wenocur A S, D'arcy M, O'Hara R J, Goldmuntz E, Grice D E, Shaikh T H, Hakonarson H, Buxbaum J D, Elia J, White P S: Rare structural variation of synapse and neurotransmission genes in autism. Molecular Psychiatry Mar 2012.Elia Josephine, Glessner Joseph T, Wang Kai, Takahashi Nagahide, Shtir Corina J, Hadley Dexter, Sleiman Patrick M A, Zhang Haitao, Kim Cecilia E, Robison Reid, Lyon Gholson J, Flory James H, Bradfield Jonathan P, Imielinski Marcin, Hou Cuiping, Frackelton Edward C, Chiavacci Rosetta M, Sakurai Takeshi, Rabin Cara, Middleton Frank A, Thomas Kelly A, Garris Maria, Mentch Frank, Freitag Christine M, Steinhausen Hans-Christoph, Todorov Alexandre A, Reif Andreas, Rothenberger Aribert, Franke Barbara, Mick Eric O, Roeyers Herbert, Buitelaar Jan, Lesch Klaus-Peter, Banaschewski Tobias, Ebstein Richard P, Mulas Fernando, Oades Robert D, Sergeant Joseph, Sonuga-Barke Edmund, Renner Tobias J, Romanos Marcel, Romanos Jasmin, Warnke Andreas, Walitza Susanne, Meyer Jobst, Pálmason Haukur, Seitz Christiane, Loo Sandra K, Smalley Susan L, Biederman Joseph, Kent Lindsey, Asherson Philip, Anney Richard J L, Gaynor J William, Shaw Philip, Devoto Marcella, White Peter S, Grant Struan F A, Buxbaum Joseph D, Rapoport Judith L, Williams Nigel M, Nelson Stanley F, Faraone Stephen V, Hakonarson Hakon: Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nature genetics 44(1): 78-84, Jan 2012.
Masino AJ, Italia MJ, Davidson LM, White PS. : Research Hospital Data ETL with DataExpress: A Scala DSL for Rapid ETL Configuration and Execution. Proceedings of Scala Days 2012.
Goldmuntz Elizabeth, Paluru Prasuna, Glessner Joseph, Hakonarson Hakon, Biegel Jaclyn A, White Peter S, Gai Xiaowu, Shaikh Tamim H: Microdeletions and microduplications in patients with congenital heart disease and multiple congenital anomalies. Congenital heart disease 6(6): 592-602, Nov-Dec 2011.
Elia J, Gai X, Hakonarson H, White PS: Structural variations in attention-deficit hyperactivity disorder. The Lancet 377: 377-378, 2011.
Elia J, Gai X, Xie H M, Perin J C, Geiger E, Glessner J T, D'arcy M, deBerardinis R, Frackelton E, Kim C, Lantieri F, Muganga B M, Wang L, Takeda T, Rappaport E F, Grant S F A, Berrettini W, Devoto M, Shaikh T H, Hakonarson H, White P S: Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes. Molecular Psychiatry 15(6): 637-46, Jun 2010.
Qu L, Vetter VL, Bird GL, Qiu H, White PS: A Naïve Bayes Classifier for Differential Diagnosis of Long QT Syndrome in Children. Proceedings of the IEEE International Conference on Bioinformatics & Biomedicine 2010 2010.
Gai Xiaowu, Perin Juan C, Murphy Kevin, O'Hara Ryan, D'arcy Monica, Wenocur Adam, Xie Hongbo M, Rappaport Eric F, Shaikh Tamim H, White Peter S: CNV Workshop: an integrated platform for high-throughput copy number variation discovery and clinical diagnostics. BMC Bioinformatics 11: 74, 2010.
Shaikh Tamim H, Gai Xiaowu, Perin Juan C, Glessner Joseph T, Xie Hongbo, Murphy Kevin, O'Hara Ryan, Casalunovo Tracy, Conlin Laura K, D'Arcy Monica, Frackelton Edward C, Geiger Elizabeth A, Haldeman-Englert Chad, Imielinski Marcin, Kim Cecilia E, Medne Livija, Annaiah Kiran, Bradfield Jonathan P, Dabaghyan Elvira, Eckert Andrew, Onyiah Chioma C, Ostapenko Svetlana, Otieno F George, Santa Erin, Shaner Julie L, Skraban Robert, Smith Ryan M, Elia Josephine, Goldmuntz Elizabeth, Spinner Nancy B, Zackai Elaine H, Chiavacci Rosetta M, Grundmeier Robert, Rappaport Eric F, Grant Struan F A, White Peter S, Hakonarson Hakon: High-resolution mapping and analysis of copy number variations in the human genome: a data resource for clinical and research applications. Genome Research 19(9): 1682-90, Sep 2009.
Fujita Tomoyuki, Igarashi Jun, Okawa Erin R, Gotoh Takahiro, Manne Jayanthi, Kolla Venkatadri, Kim Jessica, Zhao Huaqing, Pawel Bruce R, London Wendy B, Maris John M, White Peter S, Brodeur Garrett M: CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas. Journal of the National Cancer Institute 100(13): 940-9, Jul 2008.