J. Eric Russell, M.D.
Associate Professor of Medicine
Department: Medicine
Graduate Group Affiliations
Contact information
310-D Abramson Building
The Children's Hospital of Philadelphia
34th Street and Civic Center Boulevard
Philadelphia, PA 19104
The Children's Hospital of Philadelphia
34th Street and Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-3880
Fax: 215-590-2920
Fax: 215-590-2920
Email:
JERUSS@MAIL.MED.UPENN.EDU
JERUSS@MAIL.MED.UPENN.EDU
Publications
Education:
A.B. (Chemistry: magna cum laude)
Harvard University Cambridge, MA, 1980.
M.D. (Medicine)
Stanford University School of Medicine Palo Alto, CA , 1984.
Permanent linkA.B. (Chemistry: magna cum laude)
Harvard University Cambridge, MA, 1980.
M.D. (Medicine)
Stanford University School of Medicine Palo Alto, CA , 1984.
Description of Research Expertise
RESEARCH INTERESTSControl and function of human embryonic globin genes.
Key words: Globin, embryonic, sickle cell anemia, thalassemia, mRNA, prothrombin.
Selected Publications
Jiang, Y., Xu, X.-S., and Russell, J.E.: The high stability of [beta]-globin mRNA requires site-specific binding of factors that remodel the structure of its 3'UTR. The 8th Cooley's Anemia Symposium, New York Academy of Sciences, March 17-19 2005.Jiang, Y., Xu, X.-S., and Russell, J.E.: The high stability of human [beta]-globin mRNA is determined by a specific cis-element within its 3'UTR. 28th Annual Meeting of the National Sickle Cell Disease Program, Cincinnati, April 9-13 2005.
He, Z., and Russell, J.E.: Evidence that differential stabilization of [beta]-like globin mRNAs is mediated by specific determinants in their 3'UTRs. 28th Annual Meeting of the National Sickle Cell Disease Program, Cincinnati, April 9-13 2005.
Russell, J.E.: Adaptive post-transcriptional processes mitigate globin chain imbalance in [beta]-thalassemic erythrocytes. 27th Annual Meeting of the National Sickle Cell Disease Program, Los Angeles, April 18-21 2004 Notes: Oral presentation.
He, Z., and Russell, J.E.: Co-expression of human [zeta] globin corrects the sickle phenotype in mouse models of sickle cell disease. 27th Annual Meeting of the National Sickle Cell Disease Program, Los Angeles, April 18-21 2004 Notes: Oral presentation.
Frehm, E.J., Russell, J.E., and Gow, A.J.: Genetic and pharmacologic modulation of nitric oxide-hemoglobin reactivity. Eastern Society for Pediatric Research, Old Greenwich CT, March 26-28 2004 Notes: Oral presentation.
Russell, J.E.: Hemoglobinopathies and thalassemias. Medical Knowledge Self-Assessment Program 13. P.E. Epstein (eds.). Page: 30-32, 2003.