Despina Kontos, Ph.D.

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Assistant Professor of Radiology
Department: Radiology

Contact information
Computational Breast Imaging Group (CBIG)
University of Pennsylvania, Department of Radiology
3600 Market St. Suite 360
Philadelphia, PA 19104
Fax: 215-614-0266
Lab: 215-615-0827
B.Eng. (Computer Engineering and Informatics )
University of Patras, Greece, 2000.
M.Sc. (Computer and Information Sciences )
Temple University, Philadelphia PA , 2003.
Ph.D. (Computer and Information Sciences )
Temple University, Philadelphia PA , 2006.
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Description of Research Expertise

Biomedical image analysis; Quantitative imaging biomarkers; Pattern recognition; Identification, characterization and validation of imaging biomarkers; Evaluation of genotype to phenotype associations via imaging; Integrated diagnostics; Risk prediction; Personalized screening, prognostication and treatment of breast cancer.

Selected Publications

A.M.McCarthy, B.Keller, D.Kontos, L.Boghossian, E.McGuire, M.Bristol, J.Chen, S.M.Domchek, K.Armstrong: The use of the Gail Model, body mass index (BMI), and SNPs, to predict breast cancer among women with abnormal (BI-RADS 4) mammograms. Breast Cancer Research 17(1):1: [Epub ahead of print] Jan 8 2015.

AM. McCarthy, D. Kontos, M. Synnestvedt, K. Tan, D.F. Heitjan, M. Schnall, E.F. Conant: Screening Outcomes Following Implementation of Digital Breast Tomosynthesis in a General-Population Screening Program. Journal of the National Cancer Institute (JNCI) 106(11): pii: dju316. doi: 10.1093/jnci/dju316, Oct 13 2014 (in press).

Ou Y, Weinstein SP, Conant EF, Englander S, Da X, Gaonkar B, Hsieh MK, Rosen M, DeMichele A, Davatzikos C, Kontos D: Deformable registration for quantifying longitudinal tumor changes during neoadjuvant chemotherapy. Magnetic Resonance in Medicine (MRM) Jul 15 2014.

A.B. Ashraf, D. Daye, S. Gavenonis, C. Mies, M. Feldman, M. Rosen, D. Kontos: Identification of intrinsic radio-phenotypes for breast cancer tumors: Preliminary associations with gene expression profiles. Radiology 272(2): 374-84, Aug 2014.

S.Wu, S.P. Weinstein, E.F. Conant, D. Kontos: Automated fibroglandular tissue segmentation and volumetric density estimation in breast MRI using an atlas-aided fuzzy C-means method Medical Physics 40(12): 122302, Dec 2013.

A. Ashraf, S. Gavenonis, D. Daye, C. Mies, M. Feldman, M.A. Rosen, and D. Kontos: A Multichannel Markov Random Field Framework for Tumor Segmentation with an Application to Classification of Gene Expression-based Breast Cancer Recurrence Risk. IEEE Transactions on Medical Imaging 32(4): 637-48, April 2013.

B.M. Keller, D.L. Nathan, Y. Wang, Y. Zheng, J.C. Gee, E.F. Conant, D. Kontos: Estimation of Breast Percent Density in Raw and Processed Full Field Digital Mammography Images via Adaptive Fuzzy C-means Clustering and Support Vector Machine Segmentation. Medical Physics 39(8): 4903-17, Aug 2012.

D. Kontos, L. Ikejimba, P.R. Bakic, A.B. Troxel,E.F. Conant, A.D.A. Maidment: Digital Breast Tomosynthesis Parenchymal Texture Analysis: Comparison with Digital Mammography and Implications for Cancer Risk Assessment. Radiology 261(1): 80-91, Oct 2011

P.R. Bakic, A-K. Carton, D. Kontos, C. Zhang, A.B. Troxel, A.D.A. Maidment: Breast percent density estimation from mammograms and central tomosynthesis projections. Radiology 252(1): 40-9, July 2009.

V. Megalooikonomou, M. Barnathan, D. Kontos, P.R. Bakic, A.D.A Maidment: A representation and classification scheme for tree-like structures in medical images: Analyzing the branching pattern of ductal trees in x-ray galactograms IEEE Transactions on Medical Imaging 28(4): 487-93, April 2009.

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Last updated: 05/12/2015
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