Despina Kontos, Ph.D.

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Assistant Professor of Radiology
Department: Radiology

Contact information
Computational Breast Imaging Group (CBIG)
University of Pennsylvania, Department of Radiology
3600 Market St. Suite 360
Philadelphia, PA 19104
Fax: 215-614-0266
Lab: 215-615-0827
Education:
B.Eng. (Computer Engineering and Informatics )
University of Patras, Greece, 2000.
M.Sc. (Computer and Information Sciences )
Temple University, Philadelphia PA , 2003.
Ph.D. (Computer and Information Sciences )
Temple University, Philadelphia PA , 2006.
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Description of Research Expertise

Biomedical image analysis; Quantitative imaging biomarkers; Pattern recognition; Identification, characterization and validation of imaging biomarkers; Evaluation of genotype to phenotype associations via imaging; Integrated diagnostics; Risk prediction; Personalized screening, prognostication and treatment of breast cancer.

Selected Publications

A.M.McCarthy, B.Keller, D.Kontos, L.Boghossian, E.McGuire, M.Bristol, J.Chen, S.M.Domchek, K.Armstrong: The use of the Gail Model, body mass index (BMI), and SNPs, to predict breast cancer among women with abnormal (BI-RADS 4) mammograms. Breast Cancer Research 17(1):1: [Epub ahead of print] Jan 8 2015.

AM. McCarthy, D. Kontos, M. Synnestvedt, K. Tan, D.F. Heitjan, M. Schnall, E.F. Conant: Screening Outcomes Following Implementation of Digital Breast Tomosynthesis in a General-Population Screening Program. Journal of the National Cancer Institute (JNCI) 106((11)): pii: dju316. doi: 10.1093/jnci/dju316, Oct 13 2014 (accepted).

Ou Y, Weinstein SP, Conant EF, Englander S, Da X, Gaonkar B, Hsieh MK, Rosen M, DeMichele A, Davatzikos C, Kontos D: Deformable registration for quantifying longitudinal tumor changes during neoadjuvant chemotherapy. Magnetic Resonance in Medicine (MRM) Page: [Epub ahead of print, doi: 10.1002/mrm.25368] Jul 15 2014 (in press)

A.B. Ashraf, D. Daye, S. Gavenonis, C. Mies, M. Feldman, M. Rosen, D. Kontos: Identification of intrinsic radio-phenotypes for breast cancer tumors: Preliminary associations with gene expression profiles. Radiology 272(2): 374-84, Aug 2014.

S.Wu, S.P. Weinstein, E.F. Conant, D. Kontos: Automated fibroglandular tissue segmentation and volumetric density estimation in breast MRI using an atlas-aided fuzzy C-means method Medical Physics 40(12): 122302, Dec 2013.

A. Ashraf, S. Gavenonis, D. Daye, C. Mies, M. Feldman, M.A. Rosen, and D. Kontos: A Multichannel Markov Random Field Framework for Tumor Segmentation with an Application to Classification of Gene Expression-based Breast Cancer Recurrence Risk. IEEE Transactions on Medical Imaging 32(4): 637-48, April 2013.

B.M. Keller, D.L. Nathan, Y. Wang, Y. Zheng, J.C. Gee, E.F. Conant, D. Kontos: Estimation of Breast Percent Density in Raw and Processed Full Field Digital Mammography Images via Adaptive Fuzzy C-means Clustering and Support Vector Machine Segmentation. Medical Physics 39(8): 4903-17, Aug 2012.

D. Kontos, L. Ikejimba, P.R. Bakic, A.B. Troxel,E.F. Conant, A.D.A. Maidment: Digital Breast Tomosynthesis Parenchymal Texture Analysis: Comparison with Digital Mammography and Implications for Cancer Risk Assessment. Radiology 261(1): 80-91, Oct 2011

P.R. Bakic, A-K. Carton, D. Kontos, C. Zhang, A.B. Troxel, A.D.A. Maidment: Breast percent density estimation from mammograms and central tomosynthesis projections. Radiology 252(1): 40-9, July 2009.

V. Megalooikonomou, M. Barnathan, D. Kontos, P.R. Bakic, A.D.A Maidment: A representation and classification scheme for tree-like structures in medical images: Analyzing the branching pattern of ductal trees in x-ray galactograms IEEE Transactions on Medical Imaging 28(4): 487-93, April 2009.

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Last updated: 02/19/2015
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