Ethan M. Goldberg, M.D., Ph.D.

faculty photo
Assistant Professor of Neurology
Department: Neurology
Graduate Group Affiliations

Contact information
The Children's Hospital of Philadelphia
Division of Neurology
Abramson Research Center, Room 502A
3615 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-590-6894
Fax: 215-590-1771
Lab: 215-590-5671
Education:
B.A. (Neurobiology)
Harvard University, 1999.
Ph.D. (Physiology & Neuroscience)
New York University School of Medicine, 2006.
M.D.
New York University School of Medicine, 2008.
Permanent link
 

Description of Research Expertise

Epilepsy; Neurobiology of Disease; Physiology; Ion channels; Two-photon imaging.

Selected Publications

Tran, C.H., Vaiana, M., Goldstein, N., Muldoon, S.F., and Goldberg, E.M.: In vivo two-photon calcium imaging shows cell type-specific activity during seizure propagation in a model of Dravet syndrome (1.014). Poster presentation at the American Epilepsy Society Annual Meeting, Washington, D.C. December 2017.

Vaiana, M., Goldberg, E.M., and Muldoon, S.F.: Real-time, automatic calcium image segmentation via topology (721.15). Poster presentation at the Society for Neuroscience Annual Meeting, Washington, D.C. November 2017.

Favero, M., Casey, C., and Goldberg, E.M.: Developmental trajectory of interneuron dysfunction in a mouse model of Dravet syndrome (560.15). Poster presentation at the Society for Neuroscience Annual Meeting, Washington, D.C. November 2017.

Platzer Konrad, Yuan Hongjie, Schütz Hannah, Winschel Alexander, Chen Wenjuan, Hu Chun, Kusumoto Hirofumi, Heyne Henrike O, Helbig Katherine L, Tang Sha, Willing Marcia C, Tinkle Brad T, Adams Darius J, Depienne Christel, Keren Boris, Mignot Cyril, Frengen Eirik, Strømme Petter, Biskup Saskia, Döcker Dennis, Strom Tim M, Mefford Heather C, Myers Candace T, Muir Alison M, LaCroix Amy, Sadleir Lynette, Scheffer Ingrid E, Brilstra Eva, van Haelst Mieke M, van der Smagt Jasper J, Bok Levinus A, Møller Rikke S, Jensen Uffe B, Millichap John J, Berg Anne T, Goldberg Ethan M, De Bie Isabelle, Fox Stephanie, Major Philippe, Jones Julie R, Zackai Elaine H, Abou Jamra Rami, Rolfs Arndt, Leventer Richard J, Lawson John A, Roscioli Tony, Jansen Floor E, Ranza Emmanuelle, Korff Christian M, Lehesjoki Anna-Elina, Courage Carolina, Linnankivi Tarja, Smith Douglas R, Stanley Christine, Mintz Mark, McKnight Dianalee, Decker Amy, Tan Wen-Hann, Tarnopolsky Mark A, Brady Lauren I, Wolff Markus, Dondit Lutz, Pedro Helio F, Parisotto Sarah E, Jones Kelly L, Patel Anup D, Franz David N, Vanzo Rena, Marco Elysa, Ranells Judith D, Di Donato Nataliya, Dobyns William B, Laube Bodo, Traynelis Stephen F, Lemke Johannes R: GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects. Journal of medical genetics 54(7): 460-470, Jul 2017.

Shen Dingding, Hernandez Ciria C, Shen Wangzhen, Hu Ningning, Poduri Annapurna, Shiedley Beth, Rotenberg Alex, Datta Alexandre N, Leiz Steffen, Patzer Steffi, Boor Rainer, Ramsey Kerri, Goldberg Ethan, Helbig Ingo, Ortiz-Gonzalez Xilma R, Lemke Johannes R, Marsh Eric D, Macdonald Robert L: De novo GABRG2 mutations associated with epileptic encephalopathies. Brain 140: 49-67, January 2017.

Goldberg, E.M.: "Simultaneous twophoton calcium imaging and optogenetics using GCaMP6 and ChrimsonR" (92.28) Poster presentation at the Society for Neuroscience Annual Meeting in San Diego, CA. November 2016.

Tian Guoling, Cristancho Ana G, Dubbs Holly A, Liu Grant T, Cowan Nicholas J, Goldberg Ethan M: A patient with lissencephaly, developmental delay, and infantile spasms, due to de novo heterozygous mutation of KIF2A. Molecular genetics & genomic medicine 4(6): 599-603, Nov 2016.

de Kovel, C.G.F., Syrbe, S., Brilstra, E.H., Verbeek, N., Kerr, B., Dubbs, H., Bayat, A., Desai, S., Naidu, S., Srivastava, S., Cagaylan, H., Yis, U., Saunders, C., Rook, M., Plugge, S., Muhle, H., Afawi, Z., Klein, K.M., Jayaraman, V., Rajagopalan, R., Goldberg, E., Marsh, E., Kessler, S., Bergqvist, C., Conlin, L.K., Krok, B.L., Thiffault, I., Pendziwiat, M., Helbig, I., Polster, T., Borggraefe, I., Lemke, J.R., van den Boogaardt, M.J., Møller, R.S., Koeleman, B.P.C.: Neurodevelopmental Disorders Caused by De Novo Variants in KCNB1 Genotypes and Phenotypes. JAMA Neurol 74(10): 1228, Oct 2016.

Natan, R.G., Briguglio, J.J., Mwilambwe-Tshilobo, L., Jones, S., Aizenberg, M., Goldberg, E.M., Geffen, M.N.: Complementary control of sensory adaptation by two types of cortical interneurons. eLife 4: e09868, November 2015.

Tyson Jennifer A, Goldberg Ethan M, Maroof Asif M, Xu Qing, Petros Timothy J, Anderson Stewart A: Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells. Development (Cambridge, England) 142(7): 1267-78, Apr 2015.

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Last updated: 01/18/2018
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