Kristen V. Tarbell, PhD

faculty photo
Adjunct Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Graduate Group Affiliations

Contact information
Immune Tolerance Unit, Diabetes Endocrinology and Obesity Branch, NIDDK, NIH, 9000 Rockville Pike, Building 10-CRC
Room 5W-5940, MSC 1453
Bethesda, MD 20892
Office: 301-451-9360
Fax: 301-480-4518
BA (Cell Biology)
Cornell University, 1995.
PhD (Immunology)
Stanford University, 2002.
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Selected Publications

Mukherjee Gayatri, Geliebter Ari, Babad Jeffrey, Santamaria Pere, Serreze David V, Freeman Gordon J, Tarbell Kristin V, Sharpe Arlene, DiLorenzo Teresa P: DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8⁺ T cells independently of PD-1 and PD-L1. International immunology 25(11): 651-60, Nov 2013.

Price J D, Linder G, Li W P, Zimmermann B, Rother K I, Malek R, Alattar M, Tarbell K V: Effects of short-term sitagliptin treatment on immune parameters in healthy individuals, a randomized placebo-controlled study. Clinical and experimental immunology 174(1): 120-8, Oct 2013.

Gardner James M, Metzger Todd C, McMahon Eileen J, Au-Yeung Byron B, Krawisz Anna K, Lu Wen, Price Jeffrey D, Johannes Kellsey P, Satpathy Ansuman T, Murphy Kenneth M, Tarbell Kristin V, Weiss Arthur, Anderson Mark S: Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells. Immunity 39(3): 560-72, Sep 2013.

Price Jeffrey D, Beauchamp Nicole M, Rahir Gwendoline, Zhao Yongge, Rieger Cosima C, Lau-Kilby Annie W, Tarbell Kristin V: CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L. Journal of leukocyte biology Sep 2013.

Hübner Marc P, Shi Yinghui, Torrero Marina N, Mueller Ellen, Larson David, Soloviova Kateryna, Gondorf Fabian, Hoerauf Achim, Killoran Kristin E, Stocker J Thomas, Davies Stephen J, Tarbell Kristin V, Mitre Edward: Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β. Journal of immunology (Baltimore, Md. : 1950) 188(2): 559-68, Jan 2012.

Lau-Kilby Annie W, Kretz Cosima C, Pechhold Susanne, Price Jeffrey D, Dorta Stephanie, Ramos Haydee, Trinchieri Giorgio, Tarbell Kristin V: Interleukin-2 inhibits FMS-like tyrosine kinase 3 receptor ligand (flt3L)-dependent development and function of conventional and plasmacytoid dendritic cells. Proceedings of the National Academy of Sciences of the United States of America 108(6): 2408-13, Feb 2011.

Belkaid Yasmine, Tarbell Kristin V: Arming Treg cells at the inflammatory site. Immunity 30(3): 322-3, Mar 2009.

Mukhopadhaya Arunika, Hanafusa Tadashi, Jarchum Irene, Chen Yi-Guang, Iwai Yoshiko, Serreze David V, Steinman Ralph M, Tarbell Kristin V, DiLorenzo Teresa P: Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice. Proceedings of the National Academy of Sciences of the United States of America 105(17): 6374-9, Apr 2008.

Luo Xunrong, Tarbell Kristin V, Yang Hua, Pothoven Kathryn, Bailey Samantha L, Ding Ruchuang, Steinman Ralph M, Suthanthiran Manikkam: Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America 104(8): 2821-6, Feb 2007.

Tarbell Kristin V, Petit Lucine, Zuo Xiaopan, Toy Priscilla, Luo Xunrong, Mqadmi Amina, Yang Hua, Suthanthiran Manikkam, Mojsov Svetlana, Steinman Ralph M: Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. The Journal of experimental medicine 204(1): 191-201, Jan 2007.

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Last updated: 11/05/2014
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