Hyun Koo

faculty photo
Professor of Orthodontics
Department: Orthodontics
Graduate Group Affiliations

Contact information
University of Pennsylvania
School of Dental Medicine
240 South 40th Street
Philadelphia, PA 19104
State University of São Paulo, 1993.
M.S. (Food Science (Biochemistry))
State University of Campinas (UNICAMP), 1996.
Ph.D. (Oral Biology (Microbiology))
University of Rochester Medical Center, 1999.
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Selected Publications

Falsetta Megan L, Klein Marlise I, Colonne Punsiri M, Scott-Anne Kathleen, Gregoire Stacy, Pai Chia-Hua, Gonzalez-Begne Mireya, Watson Gene, Krysan Damian J, Bowen William H, Koo Hyun: Symbiotic relationship between Streptococcus mutans and Candida albicans synergizes virulence of plaque biofilms in vivo. Infection and immunity 82(5): 1968-81, May 2014.

Koo H, Falsetta M L, Klein M I: The exopolysaccharide matrix: a virulence determinant of cariogenic biofilm. Journal of dental research 92(12): 1065-73, Dec 2013.

Hsu Jeff C, Koo Hyun, Harunaga Jill S, Matsumoto Kazue, Doyle Andrew D, Yamada Kenneth M: Region-specific epithelial cell dynamics during branching morphogenesis. Developmental dynamics : an official publication of the American Association of Anatomists 242(9): 1066-77, Sep 2013.

Bueno-Silva Bruno, Alencar Severino M, Koo Hyun, Ikegaki Masaharu, Silva Gil V J, Napimoga Marcelo H, Rosalen Pedro L: Anti-inflammatory and antimicrobial evaluation of neovestitol and vestitol isolated from Brazilian red propolis. Journal of agricultural and food chemistry 61(19): 4546-50, May 2013.

Lemos José A, Quivey Robert G, Koo Hyun, Abranches Jacqueline: Streptococcus mutans: a new Gram-positive paradigm? Microbiology (Reading, England) 159(Pt 3): 436-45, Mar 2013.

Bueno-Silva B, Koo H, Falsetta M L, Alencar S M, Ikegaki M, Rosalen P L: Effect of neovestitol-vestitol containing Brazilian red propolis on accumulation of biofilm in vitro and development of dental caries in vivo. Biofouling 29(10): 1233-42, 2013.

da Cunha Marcos Guilherme, Franchin Marcelo, de Carvalho Galvão Lívia Câmara, de Ruiz Ana Lúcia Tasca Góis, de Carvalho João Ernesto, Ikegaki Masarahu, de Alencar Severino Matias, Koo Hyun, Rosalen Pedro Luiz: Antimicrobial and antiproliferative activities of stingless bee Melipona scutellaris geopropolis. BMC complementary and alternative medicine 13: 23, 2013.

Feng Guoping, Klein Marlise I, Gregoire Stacy, Singh Ajay P, Vorsa Nicholi, Koo Hyun: The specific degree-of-polymerization of A-type proanthocyanidin oligomers impacts Streptococcus mutans glucan-mediated adhesion and transcriptome responses within biofilms. Biofouling 29(6): 629-40, 2013.

Falsetta Megan L, Klein Marlise I, Lemos José A, Silva Bruno B, Agidi Senyo, Scott-Anne Kathy K, Koo Hyun: Novel antibiofilm chemotherapy targets exopolysaccharide synthesis and stress tolerance in Streptococcus mutans to modulate virulence expression in vivo. Antimicrobial agents and chemotherapy 56(12): 6201-11, Dec 2012.

Klein M I, Scott-Anne K M, Gregoire S, Rosalen P L, Koo H: Molecular approaches for viable bacterial population and transcriptional analyses in a rodent model of dental caries. Molecular oral microbiology 27(5): 350-61, Oct 2012.

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Last updated: 08/23/2013
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