Andre Nussenzweig, PhD

faculty photo
Adjunct Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Graduate Group Affiliations

Contact information
Center for Cancer Research
National Cancer Institute
Building 37, Room 1106A
Bethesda, MD 20892-4254
Office: 301-435-6425
Education:
BA (Physics)
New York University, 1983.
PhD (Physics)
Yale University, 1989.
Permanent link
 

Selected Publications

Li Minxing, Cole Francesca, Patel Dharm S, Misenko Sarah M, Her Joonyoung, Malhowski Amy, Alhamza Ali, Zheng Haiyan, Baer Richard, Ludwig Thomas, Jasin Maria, Nussenzweig André, Serrano Lourdes, Bunting Samuel F: 53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1. EMBO reports 11: 1532-1541, Nov 2016 Notes: Epub 2016 Sep 26.

Chaudhuri Arnab Ray, Callen Elsa, Ding Xia, Gogola Ewa, Duarte Alexandra A, Lee Ji-Eun, Wong Nancy, Lafarga Vanessa, Calvo Jennifer A, Panzarino Nicholas J, John Sam, Day Amanda, Crespo Anna Vidal, Shen Binghui, Starnes Linda M, de Ruiter Julian R, Daniel Jeremy A, Konstantinopoulos Panagiotis A, Cortez David, Cantor Sharon B, Fernandez-Capetillo Oscar, Ge Kai, Jonkers Jos, Rottenberg Sven, Sharan Shyam K, Nussenzweig André: Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature 539(7629): 456, Nov 2016 Notes: Correction. doi: 10.1038/nature19826. Epub 2016 Sep 28.

Morgado-Palacin Isabel, Day Amanda, Murga Matilde, Lafarga Vanesa, Anton Marta Elena, Tubbs Anthony, Chen Hua-Tang, Ergan Aysegul, Anderson Rhonda, Bhandoola Avinash, Pike Kurt G, Barlaam Bernard, Cadogan Elaine, Wang Xi, Pierce Andrew J, Hubbard Chad, Armstrong Scott A, Nussenzweig André, Fernandez-Capetillo Oscar: Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML. Science signaling 9(445): ra91, Sep 2016 Notes: doi: 10.1126/scisignal.aad8243.

Canela Andres, Sridharan Sriram, Sciascia Nicholas, Tubbs Anthony, Meltzer Paul, Sleckman Barry P, Nussenzweig André: DNA Breaks and End Resection Measured Genome-wide by End Sequencing. Molecular cell 63(5): 898-911, Sep 2016.

Nieto-Soler Maria, Morgado-Palacin Isabel, Lafarga Vanesa, Lecona Emilio, Murga Matilde, Callen Elsa, Azorin Daniel, Alonso Javier, Lopez-Contreras Andres J, Nussenzweig Andre, Fernandez-Capetillo Oscar: Efficacy of ATR inhibitors as single agents in Ewing sarcoma. Oncotarget 7(37): 58759-58767, Sep 2016 Notes: doi: 10.18632/oncotarget.11643.

Ding Xia, Ray Chaudhuri Arnab, Callen Elsa, Pang Yan, Biswas Kajal, Klarmann Kimberly D, Martin Betty K, Burkett Sandra, Cleveland Linda, Stauffer Stacey, Sullivan Teresa, Dewan Aashish, Marks Hanna, Tubbs Anthony T, Wong Nancy, Buehler Eugen, Akagi Keiko, Martin Scott E, Keller Jonathan R, Nussenzweig André, Sharan Shyam K: Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies. Nature communications 7: 12425, Aug 2016 Notes: doi: 10.1038/ncomms12425.

Zong Dali, Chaudhuri Arnab Ray, Nussenzweig André: More end resection is not merrier. Nature structural & molecular biology 23(8): 699-701, Aug 2016.

Ray Chaudhuri Arnab, Callen Elsa, Ding Xia, Gogola Ewa, Duarte Alexandra A, Lee Ji-Eun, Wong Nancy, Lafarga Vanessa, Calvo Jennifer A, Panzarino Nicholas J, John Sam, Day Amanda, Crespo Anna Vidal, Shen Binghui, Starnes Linda M, de Ruiter Julian R, Daniel Jeremy A, Konstantinopoulos Panagiotis A, Cortez David, Cantor Sharon B, Fernandez-Capetillo Oscar, Ge Kai, Jonkers Jos, Rottenberg Sven, Sharan Shyam K, Nussenzweig André: Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature 535(7612): 382-7, Jul 2016.

Iqbal Javaid, Nussenzweig Andre, Lubinski Jan, Byrski Tomasz, Eisen Andrea, Bordeleau Louise, Tung Nadine M, Manoukian Siranoush, Phelan Catherine M, Sun Ping, Narod Steven A: The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study. British journal of cancer 114(10): 1160-4, May 2016.

Salewsky Bastian, Hildebrand Gabriele, Rothe Susanne, Parplys Ann Christin, Radszewski Janina, Kieslich Moritz, Wessendorf Petra, Krenzlin Harald, Borgmann Kerstin, Nussenzweig André, Sperling Karl, Digweed Martin: Directed Alternative Splicing in Nijmegen Breakage Syndrome: Proof of Principle Concerning Its Therapeutical Application. Molecular therapy : the journal of the American Society of Gene Therapy 24(1): 117-24, Feb 2016.

back to top
Last updated: 03/09/2017
The Trustees of the University of Pennsylvania