David M. Raizen, MD, PhD

faculty photo
Assistant Professor of Neurology
Department: Neurology
Graduate Group Affiliations

Contact information
Dept Neurology
462 Stemmler Hall
415 Curie Blvd
Philadelphia, PA 19104-4283
Education:
BA (Biochemistry)
University of Texas at Austin, 1989.
MD (Medicine)
University of Texas Southwestern, 1997.
PhD (Neuroscience)
University of Texas Southwestern, 1997.
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Description of Research Expertise

C. elegans behavioral genetics. Regulation of sleep-like states. Function of sleep and sleep-like states.

Selected Publications

Zimmerman JE, Raizen DM, Maycock MH, Maislin G, Pack AI.: A video method to study Drosophila sleep. Sleep 31(11): 1587-1598, November 2008.

David M. Raizen, John E. Zimmerman, Matthew H. Maycock, Uyen D. Ta, Young-jai You, Meera V. Sundaram & Allan I. Pack: Lethargus is a Caenorhabditis elegans sleep-like state. Nature 451, January 2008.

You, Y., Kim, J., Raizen, D. M., and Avery, L.: Insulin, cGMP and TGF-ß signals regulate food intake and quiescence in C. elegans: a model for satiety Cell Metabolism 7: 249-257, 2008.

Zimmerman, J. E., Raizen, D. M., Shockley, K., Churchill, G. A., and Pack, A. I.: Temporal changes in gene expression with sleep and wake in the Drosophila brain. Physiological Genomics 27(3): 337-350, September 2006.

Raizen, D. M., Cullison, K. M., Pack, A. I, and Sundaram, M. V.: A novel gain-of-function mutant of the cGMP-dependent protein kinase egl-4 affects multiple physiological processes in C. elegans. Genetics 173(1): 177-187, May 2006.

Raizen, D. M., Brooks-Kayal, A., Steinkrauss, L., Tennekoon, G. I., Stanley, C. A., and Kelly, A.: Central nervous system hyperexcitability associated with glutamate dehydrogenasae gain of function mutations. Journal of Pediatrics 146(3): 388-394, March 2005.

McKay, J. P., Raizen, D. M., Gottschalk, A., Schafer, W. R., and Avery, L.: eat-2 and eat-18 are required for nicotinic neurotransmission in the C. elegans pharynx. Genetics 166(1): 161-169, January 2004.

Taylor, R. A., Virgilio, J. A., Shapiro, M., Raizen, D. M., Hunt, J., Rook, A., and Bagg, A.: T-cell receptor gamma-chain gene PCR to diagnose CNS involvement by cutaneous T-cell lymphoma. Journal of Molecular Diagnostics 4(2): 118-120, 2002.

Hinkle, D. A., Raizen, D. M., McGarvey, M. L., Liu, G. T.: Cerebral air embolism complicating cardiac ablation procedures. Neurology 56(6): 792-794, March 2001.

Kleopas, K. A., Raizen, D. M., Friedrich, C. A., Brown, M. J., and Bird, S. J: Acute axonal neuropathy in Maple Syrup Urine Disease. Muscle and Nerve 24: 284-287, 2001.

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Last updated: 08/24/2010
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