Penn Comprehensive Neuroscience Center

Faculty Members
faculty photo

Timothy H Lucas Jr., M.D., Ph.D.

Assistant Professor of Neurosurgery
Director, Translational Neuromodulation Laboratory, Department of Neurosurgery, University of Pennsylvania
Associate Director, Center for Neuroengineering & Therapeutics, University of Pennsylvania
Department: Neurosurgery

Contact information
3400 Spruce Street
3rd Floor Silverstein
Philadelphia, PA 19104
Office: 215-615-0578
Fax: 215-349-5534
Lab: 215-746-1336
Graduate Group Affiliations
B.S. (Neurobiological Sciences & Psychobiology)
University of Florida, 1996.
M.D. (Medicine)
University of Florida, 2001.
Ph.D. (Physiology & Biophysics)
University of Washington, 2009.
Post-Graduate Training
Intern in General Surgery, University of Washington, 2001-2002.
Resident in Neurological Surgery, University of Washington, 2002-2009.
Specialist Registrar in Neurological Surgery, St. George's National Healthcare Trust, London, England, UK, 2006-2007.
Chief Resident in Neurological Surgery, University of Washington, 2009-2010.
Fellow in Neurosurgical Oncology & Cerebrovascular Neurosurgery, University of Washington, 2010-2010.
Clinical Experience in Stereotactic & Functional Neurosurgery, University of California San Francisco, 2011-2011.
Fellow in Neurosurgical Oncology Brain Mapping, University of California San Francisco, 2011-2011.
American Board of Neurological Surgeons (Board Eligible), 2011.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Description of Clinical Expertise

Epilepsy Surgery
Temporal Lobectomy
Minimally invasive neurosurgery
Laser Neurosurgery
Endoscopic Surgery
Sports Neurosurgery
Cortisectomy / Topectomy
Corpus Callostomy / Functional Disconnection Surgery
Trigeminal neuralgia
Microvascular decompression
Stereotactic and Functional Neurosurgery
Movement Disorder Surgery (Parkinson's Disease, Essential Tremor, Dystonia)
Glioma Surgery (Low Grade, High Grade, Adult, Pediatric)
Insular Lesions
Brain Mapping (Speech, Motor, Sensory; cortical and subcortical)
Extraoperative Brain Mapping
Brain-machine interface / Brain-computer interface
Spine Disorders
Spinal Fusion
Skull base surgery
Brain Plasticity
Eloquent Cortex Lesions (motor, sensory, speech, visual cortex)
Traumatic brain and spine injury

Description of Research Expertise

Brain-machine interface / Brain-computer interface
Motor Cortex Functional Organization
Voluntary Movement
Speech and Language Organization
Cortical Plasticity
Basal Ganglia - Cortical Interactions
Cortical/Basal Ganglia Stimulation
Cortical Spike and Local Field Recording
Basal Ganglia Spike and Local Field Recording
Spinal Cord Stimulation and Mapping

Selected Publications

Richardson, Andrew G, Attiah, Mark A, Berman, Jeffrey I, Chen, H Isaac, Liu, Xilin, Zhang, Milin, Van der Spiegel, Jan, Lucas, Timothy H: The effects of acute cortical somatosensory deafferentation on grip force control. Cortex 74: 1-8, 2016.

Khambhati, Ankit N, Davis, Kathryn A, Lucas, Timothy H, Litt, Brian, Bassett, Danielle S: Virtual cortical resection reveals push-pull network control mechanism preceding seizure evolution. bioRxiv Page: 055566, 2016.

Dichter, Marc A, Lucas, Timothy H, Viventi, Jonathan, Litt, Brian, Rogers, John A: Bioresorbable silicon electronics for transient spatiotemporal mapping of electrical activity from the cerebral cortex. 2016.

Thawani, Jayesh P, Lucas, Timothy H: Open traumatic brain injury by nail gun resulting in a persistent vegetative state. Neurology 86(14): 1358-1359, 2016.

Richardson, Andrew G, Weigand, Pauline K, Sritharan, Srihari Y, Lucas, Timothy H: A chronic neural interface to the macaque dorsal column nuclei. Journal of neurophysiology 115(5): 2255-2264, 2016.

Davis Kathryn Adamiak, Nanga Ravi Prakash Reddy, Das Sandhitsu, Chen Stephanie H, Hadar Peter N, Pollard John R, Lucas Timothy H, Shinohara Russell T, Litt Brian, Hariharan Hari, Elliott Mark A, Detre John A, Reddy Ravinder: Glutamate imaging (GluCEST) lateralizes epileptic foci in nonlesional temporal lobe epilepsy. Science translational medicine 7(309): 309ra161, Oct 2015.

Chen H Isaac, Bohman Leif-Erik, Emery Lyndsey, Martinez-Lage Maria, Richardson Andrew G, Davis Kathryn A, Pollard John R, Litt Brian, Gausas Roberta E, Lucas Timothy H: Lateral Transorbital Endoscopic Access to the Hippocampus, Amygdala, and Entorhinal Cortex: Initial Clinical Experience. ORL; journal for oto-rhino-laryngology and its related specialties 77(6): 321-332, Sep 2015.

Abdullah Kalil G, Attiah Mark A, Olsen Andrew S, Richardson Andrew, Lucas Timothy H: Reducing surgical site infections following craniotomy: examination of the use of topical vancomycin. Journal of neurosurgery Page: 1-5, Jun 2015.

Liu Xilin, Zhang Milin, Subei Basheer, Richardson Andrew G, Lucas Timothy H, Van der Spiegel Jan: The PennBMBI: Design of a General Purpose Wireless Brain-Machine-Brain Interface System. IEEE transactions on biomedical circuits and systems 9(2): 248-58, Apr 2015.

Richardson, Andrew G, Weigand, Pauline K, Sritharan, Srihari Y, Lucas, Timothy H: Somatosensory encoding with cuneate nucleus microstimulation: effects on downstream cortical activity. IEEE, Page: 695-698, 2015.

back to top
Last updated: 06/27/2016
The Trustees of the University of Pennsylvania