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Michael E. Selzer, MD, PhD

Emeritus Professor of Neurology
Chief, Division of Neurorehabilitation, Department of Neurology, University of Pennsylvania School of Medicine
Department: Neurology

Contact information
450 Stemmler Hall, 3450 Hamilton Walk, Department of Neurology
Philadelphia, PA 19104-6077
Office: (215) 898-0180
Fax: (215) 573-2107
Education:
B.A.
University of Pennsylvania, 1962.
M.D.
New York University, 1968.
Ph.D.
New York University, 1968.
Post-Graduate Training
Fellowship, USPHS Medical Scientist Training Program (M.D., Ph.D. program), New York University, 1964-1968.
Intern in Medicine, Bellevue Hospital, New York, 1968-1969.
Staff Associate, Laboratory of Perinatal Physiology, NINDS, National Institutes of Health, 1969-1971.
Resident in Neurology, Hospital of the Univ. of PA, 1971-1974.
Certifications
American Board of Psychiatry and Neurology, 1976.
American Society of Neurorehabilitation, 1992.
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Description of Research Expertise

RESEARCH INTERESTS
Spinal cord regeneration in lamprey

KEY WORDS:
axon regeneration; central nervous system; neurofilament; glial cells; lamprey; axon guidance

RESEARCH TECHNIQUES
Immunocytochemistry; molecular cloning and sequencing; in-situ hybridization; intracellular recording; intracellular injection of tracers (HRP, etc), drugs and molecular agents; anatomical pathway tracing with retrograde labels; electron microscopy

Description of Clinical Expertise

Sees patients with epilepsy, trigeminal neuralgia. Advises patients on neurorehabilitation.

Selected Publications

Pizarro IV, Swain GP, Selzer ME: Cell proliferation in the lamprey central nervous system. J Comp Neurol 469: 298-310, Feb 2004.

Zhang G, Spencer PH, Jin L-Q, Cohlberg JA, Beaulieu JM, Julien J-P, Selzer ME: The single neurofilament subunit of lamprey may need another element for filament assembly. J Comp Neurol 471: 188-200, 2004.

Selzer ME, Jones SL, Gallo G: Actin-independent mechanism of axon regeneration. 56th Annual Meeting of the American Academy of Neurology April 2004.

Popescu A, Uematsu, Wehrli SL, Wehrli FW, Wright AC, Zhang G, Selzer ME, Hackney DB: Magnetization transfer micro imaging characterization of axonal degeneration and regeneration in live excised lamprey spinal cord. 12th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Kyoto, Japan May 2004.

Wright AC, Uematsu H, Popescu A, Zhang G, Wehrli SL, Hackney DB, Selzer ME, Wehrli FW: In vivo MRI of lamprey spinal cord. 12th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Kyoto, Japan May 2004.

Takahashi, M, Uematsu H, Zhang G, Popescu A, Selzer ME, Hackney DB: Diffusion-weighted micro MR studies of axonal regeneration in live injured excised larval sea lamprey spinal cord. 11th Annual of Meeting of the International Society of Magnetic Resonance in Medicine, Toronto May 2003.

Wright AC, Uematsu H,, Popescu A, Zhang G, Wehrli SL, Hackney DB, Selzer ME, Wehrli FW: In vivo MR microscopy of lamprey spinal cord. 11th Annual of Meeting of the International Society of Magnetic Resonance in Medicine, Toronto May 2003.

Popescu A, Hackney DB, Uematsu H, Wehrli SL, Wehrli FW, Wright AC, Zhang G, Takahashi M, Selzer ME: Micro MR imaging of live normal lamprey cord using magnetization transfer contrast. 11th Annual of Meeting of the International Society of Magnetic Resonance in Medicine, Toronto May 2003.

Jones SL, Gallo G, Selzer ME: Developmental changes in actin filament requirement for axon extension. 33rd Annual Meeting of the Society for Neuroscience 2003.

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Last updated: 10/22/2007
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