Penn Comprehensive Neuroscience Center

Faculty Members
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David A Wolk, MD

Associate Professor of Neurology
Assistant Director, Penn Memory Center
Attending Neurologist, Hospital of the University of Pennsylvania
Faculty, Center for Cognitive Neuroscience, University of Pennsylvania
Fellow, Institute on Aging, University of Pennsylvania
Department: Neurology

Contact information
Penn Memory Center
Ralston House
#212A
3615 Chestnut Street
Philadelphia, PA 19104
Office: 215 662-7810
Fax: 215 662-7812
Graduate Group Affiliations
Education:
BA (Psychology)
Dartmouth College, 1994.
MD (Medicine)
Johns Hopkins University School of Medicine, 1998.
Post-Graduate Training
Intern in Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 1998-1999.
Resident in Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 1999-2002.
Fellow in Cognitive Neurology, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, 2002-2004.
Post-doctoral Research Fellow, Harvard University, Cambridge, MA, Brigham and Women's Hospital, Boston, MA, 2003-2006.
Certifications
Diplomate of the American Board of Psychiatry And Neurology, Inc. , 2003.
Subspecialty Certification in Behavioral Neurology and Neuropsychiatry by the United Council of Neurologic Subspecialties, 2012.
Permanent link
 
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Description of Research Expertise

Episodic Memory, Event-related Potentials, transcranial direct current stimulation, MRI, Alzheimer's Disease, Dementia, Memory Disorders, Cognitive Neurology, Aging,

Description of Clinical Expertise

Alzheimer's Disease, Dementia, Memory Disorders, Cognitive Neurology

Selected Publications

Wolk DA, Dickerson BC : Fractionating verbal episodic memory in Alzheimer's disease. NeuroImage 54(2): 1530-9, Sep 2010.

Wolk DA, Dickerson BC: Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America 107(22): 10256-61, Jun 2010 Notes: Featured article in Alzheimer Research Forum: ApoE and Brain Networks—The Anatomy of a Risk Factor, May 28, 2010.

Wolk DA, Dunfee KL, Dickerson BC, Aizenstein HJ, Dekosky ST: A medial temporal lobe division of labor: Insights from memory in aging and early Alzheimer disease. Hippocampus 21(5): 461-6, Mar 2010.

Wolk DA, Price JC, Saxton JA, Snitz BE, James JA, Lopez OL, Aizenstein HJ, Cohen AD, Weissfeld LA, Mathis CA, Klunk WE, DeKosky ST: Amyloid imaging in mild cognitive impairment subtypes. Annals of Neurology 65(5): 557-68, May 2009.

Dickerson BC, Wolk DA: MRI cortical thickness biomarker predicts AD-like CSF and cognitive decline in normal adults. Neurology 78(2): 84-90, Dec 2011 Notes: Featured editorial on manuscript: Resnick SM; Scheltens P. MRI-based biomarkers of preclinical AD: An Alzheimer signature. Neurology: 78(2): 80-81. Featured article in Alzheimer Research Forum. Is Structural MRI Closing In on Preclinical AD Biomarker? December 27, 2011.

Pluta J, Yushkevich P, Das S, Wolk D: In vivo Analysis of Hippocampal Subfield Atrophy in Mild Cognitive Impairment via Semi-Automatic Segmentation of T2-Weighted MRI. Journal of Alzheimer's Disease 31(1): 85-99, Jan 2012.

Wolk DA, Price JC, Madeira C, Saxton JA, Snitz BE, Lopez OL, Mathis CA, Klunk WE, Dekosky ST: Amyloid imaging in dementias with atypical presentation. Alzheimer's & Dementia Jan 2012.

Wolk David A, Mancuso Lauren, Kliot Daria, Arnold Steven E, Dickerson Bradford C: Familiarity-based memory as an early cognitive marker of preclinical and prodromal AD. Neuropsychologia 51(6): 1094-102, Mar 2013.

Wolk DA: Amyloid Imaging in Atypical Presentations of Alzheimer’s Disease. Current Neurology and Neuroscience Reports In press.

Wolk DA, Manning K, Kliot D, Arnold SE : Recognition Memory in Amnestic-Mild Cognitive Impairment: Insights from Event-Related Potentials. Frontiers in Aging Neuroscience in press.

Dickerson BC, Wolk DA: Biomarker-based prediction of progression in MCI: Comparison of AD-signature and hippocampal volume with spinal fluid amyloid-ß and tau. Frontiers in Aging Neuroscience In press.

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Last updated: 06/13/2014
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