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Jay D. Amsterdam, M.D.

Emeritus Professor CE of Psychiatry
Director, Bipolar Disorders and Lithium Clinic
Department: Psychiatry

Contact information
Depression Research Unit
3535 Market Street, 3rd Floor
Philadelphia, PA 19104-3309
Office: (215) 662-3462
Fax: (215) 662-6443
Syracuse University, Syracuse, New York, 1970.
Jefferson Medical College, Philadelphia, Pennsylvania, 1974.
Post-Graduate Training
Intern in Obstetrics/Gynecology, Upstate Medical Center, Syracuse, New York, 1974-1974.
Resident in Psychiatry, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, 1974-1977.
Chief Resident in Psychiatry, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, 1976-1977.
Clinical Attachment, Maudsley Hospital at The Institute of Psychiatry, University of London, England, 1976-1976.
Senior Resident, Psychiatric Research Service, Depression Research Unit, Veterans Administration Medical Center, Philadelphia, PA , 1977-1978.
N.I.M.H. Postdoctoral Fellow in Neuropsychopharmacology - Depression Research Unit, Department of Psychiatry, Veterans Administration Hospital, Hospital of the University of Pennsylvania, 1978-1979.
Diplomate, National Board of Medical Examiners, 1975.
Diplomate, American Board of Psychiatry and Neurology, 1979.
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Description of Research Expertise

1) Psychopharmacology of Affective Disorders
2) Antidepressant Drug Development
3) Investigational Clinical Trials
4) Bipolar Affective Disorders
5) Treatment-resistant Affective Disorders
6) Brain Imaging Studies
7) Psychoneuroendocrinology of Affective disorders
8) Psychoimmunovirology
9) Clinical Pharmacokinetics
10)Complementary & Alternative Medicine

Selected Publications

Amsterdam, J.D., Newberg, A: Dopamine Transporter Density in Bipolar Type II and Unipolar Major Depressive Episode. Neuropsychobiology 55: 167-170, 2007.

Michelson D, Adler L, Amsterdam JD, Dunner D, Nierenberg A, Reimherr F, Schatzberg Am Kelsey D, Williams D: Addition of atomoxetine for depression incompletely responsive to sertraline: A randomized, double blind, placebo controlled study. Journal of Clinical Psychiatry 68: 582-587, 2007.

Newberg AB, Amsterdam JD, Shults J: Dopamine transporter density may be associated with the depressed affect in healthy subjects. Nuclear Medicine Communications 28(1): 3-6, 2007.

Amsterdam JD: Monoamine oxidase inhibitor therapy in severe and resistant depression. Psychiatric Annals 36(9): 606-617, 2006.

Amsterdam JD, Bodkin JA: Selegiline transdermal system and the prevention of relapse of major depressive disorder: a 52-week, double-blind placebo substitution parallel group clinical trial. Journal of Clinical Psychopharmacology 26: 579-586, 2006.

DeRubeis RJ, Hollon SD, Amsterdam JD, Shelton RC, Young PR, Salomon RM, O'Reardon JP, Lovett ML, Gladis MM, Brown LL, Gallop R, : Cognitive therapy vs. medications in treatment of moderate to severe depression. Archives of General Psychiatry 62: 409-416, 2005.

Hollon SD, DeRubeis RJ, Shelton RC, Amsterdam JD, Salomon RM, O'Reardon JP, Lovett ML, Young PR, Haman KL, Freeman BB, Gallop R : Prevention of relapse following cognitive therapy versus medications in moderate to severe depression. Archives of General Psychiatry 62: 417-422, 2005.

Amsterdam JD, Rutherford N, Shults J: Antidepressant monotherapy of major depressive episode in bipolar II disorder: A therapeutic change. Psychiatric Annals 35(12): 981-992, 2005.

Amsterdam JD, Shults J: MAOI safety and efficacy in advanced treatment-resistant depression - a retrospective analysis. Journal of Affective Disorders 89: 183-188, 2005.

Amsterdam JD, Shults J: Fluoxetine monotherapy for bipolar type II and bipolar NOS major depression - A double-blind, placebo-substitution, continuation study. International Clinical Psychopharmacology 20: 357-364, 2005.

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Last updated: 03/26/2010
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