Selected Publications

Zillich L, D'Augello S, Avetyan D, Delgado GE, Gizer IR, Jung J, Katrinli S, Kleber ME, Merrill N, Moissl AP, Núñez-Rios DL, Otto JM, Zillich E, Friedel E, Hancock DB, Johnson EO, Martínez-Magaña JJ, Nagamatsu ST, Sosnowski DW, White JD, Aberg KA, Copeland WE, Diazgranados N, Fani N, Gelernter J, Goldman D, Foo JC, Kranzler HR, Levey DF, März W, Penninx BWJH, Polimanti R, Powers A, Smith AK, Spanagel R, van den Oord EJCG, Wilhelmsen KC, Witt SH, Domschke K, Schiele MA, Maher BS, Montalvo Ortiz JL, Clark SL, Lohoff FW.: DNA Methylation Signatures of Alcohol Use Disorder - A large-scale Meta-Analysis in the Psychiatric Genomics Consortium. medRxiv Sep 2025.

Witkiewitz K, Anton RF, O'Malley SS, Hasin DS, Silverman BL, Aldridge A, Mann K; Alcohol Clinical Trials Initiative (ACTIVE) Workgroup.: Reductions in World Health Organization Risk Drinking Levels as a Primary Efficacy End Point for Alcohol Clinical Trials: A Review. JAMA Psychiatry Sep 2025.

Jinwala Z, Davis CN, SooHoo JF; Million Veteran Program; Penn Medicine Biobank; Gelernter J, Kember RL, Vickers-Smith R, Kranzler HR.: Multi-ancestry Genome-wide Association Study of Inpatient Opioid Dosing Following Knee or Hip Arthroplasty. Res Sq Aug 2025.

Han A, Davis CN, Jinwala Z, SooHoo J, Gelernter J, Feinn R, Kranzler HR.: Polygenic risk and childhood adversity as moderators of drug and alcohol withdrawal symptoms. Drug Alcohol Depend 273: 112712, Aug 2025.

Ebert JP, Kranzler HR, Barnett IJ, Hemmons JE, Yan R, Spencer E, Delgado MK.: Effect of smartphone breathalyzer feedback on willingness to drive in moderately intoxicated individuals: A randomized trial. Psychol Addict Behav Aug 2025.

Johnson EC, Lai D, Balbona JV, Miller AP, Hatoum AS, Deak JD, Jennings M, Baranger DAA, Galimberti M, Sanichwankul K, Thorgeirsson T, Colbert SMC, Adhikari K, Docherty AR, Degenhardt L, Edwards T, Fox L, Giannelis A, Jeffries PW, Korhonen T, Morrison CL, Nunez YZ, Palviainen T, Su MH, Romero Villela PN, Wetherill L, Willoughby EA, Zellers SM, Bierut LJ, Buchwald J, Copeland WE, Corley RP, Friedman NP, Foroud TM, Gillespie NA, Gizer IR, Heath AC, Hickie IB, Kaprio J, Keller MC, Lee JJ, Lind P, Madden PA, Maes HHM, Martin NG, McGue M, Medland SE, Nelson EC, Pearson J, Porjesz B, Stallings MC, Vrieze S, Wilhelmson KC, Kranzler HR, Walters RK, Polimanti R, Malison R, Zhou H, Stefansson K, Sanchez-Roige S, Potenza M, Mutirangura A, Shotelersuk V, Kalayasiri R, Edenberg HJ, Gelernter J, Agrawal A.: Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. Psychol Med 55: e234, Aug 2025.

Middleton SJ, Markússon S, Åkerlund M, Deme JC, Tseng M, Li W, Zuberi SR, Kuteyi G, Sarkies P, Baskozos G, Perez-Sanchez J, Farah A, Hébert HL, Toikumo S, Yu Z, Maxwell S, Dong YY, Kessler BM, Kranzler HR, Linley JE, Smith BH, Lea SM, Parker JL, Lyssenko V, Newstead S, Bennett DL.: SLC45A4 is a pain gene encoding a neuronal polyamine transporter. Nature Aug 2025.

Toikumo S, Parisien M, Leone MJ, Srinivasan C, Yu H, Arendt-Tranholm A, Franco-Enzástiga Ú, Hofstetter C, Curatolo M, Luo W, Pfenning AR, Seal RP, Kember RL, Price TJ, Diatchenko L, Waxman SG, Kranzler HR.: Etiological basis for chronic pain genetic variation in brain and dorsal root ganglia cell types. medRxiv Jul 2025.

Wang L, Kranzler HR, Gelernter J, Zhou H.: Investigating the Contribution of Coding Variants in Alcohol Use Disorder Using Whole-Exome Sequencing Across Ancestries. Biol Psychiatry 98: 46-55, Jul 2025.

Dubroff JG, Hsieh CJ, Wiers CE, Lee H, Schmitz A, Li EJ, Schubert EK, Mach RH, Kranzler HR.: [(11)C]Carfentanil PET Whole-Body Imaging of μ-Opioid Receptors: A First in-Human Study. J Nucl Med 66: 1112-1118, Jul 2025.