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Faculty Members:
Jay D. Amsterdam, M.D.
Professor of Psychiatry at the Hospital of the University of Pennsylvania
Director
Department: Psychiatry
Contact information
Depression Research Unit
3535 Market Street, 3rd Floor
Philadelphia, PA 19104-3309
3535 Market Street, 3rd Floor
Philadelphia, PA 19104-3309
Office: (215) 662-3462
Fax: (215) 662-6443
Fax: (215) 662-6443
Email:
jamsterd@mail.med.upenn.edu
jamsterd@mail.med.upenn.edu
Education:
B.A.
Syracuse University, Syracuse, New York, 1970.
M.D.
Jefferson Medical College, Philadelphia, Pennsylvania, 1974.
B.A.
Syracuse University, Syracuse, New York, 1970.
M.D.
Jefferson Medical College, Philadelphia, Pennsylvania, 1974.
Post-Graduate Training
Resident in Psychiatry, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, 1974-1977.
Intern in Obstetrics/Gynecology, Upstate Medical Center, Syracuse, New York, 1974-1974.
Chief Resident in Psychiatry, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, 1976-1977.
Clinical Attachment, Maudsley Hospital at The Institute of Psychiatry, University of London, England, 1976-1976.
Senior Resident, Psychiatric Research Service, Depression Research Unit, Veterans Administration Medical Center, Philadelphia, PA , 1977-1978.
N.I.M.H. Postdoctoral Fellow in Neuropsychopharmacology - Depression Research Unit, Department of Psychiatry, Veterans Administration Hospital, Hospital of the University of Pennsylvania, 1978-1979.
Resident in Psychiatry, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, 1974-1977.
Intern in Obstetrics/Gynecology, Upstate Medical Center, Syracuse, New York, 1974-1974.
Chief Resident in Psychiatry, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, 1976-1977.
Clinical Attachment, Maudsley Hospital at The Institute of Psychiatry, University of London, England, 1976-1976.
Senior Resident, Psychiatric Research Service, Depression Research Unit, Veterans Administration Medical Center, Philadelphia, PA , 1977-1978.
N.I.M.H. Postdoctoral Fellow in Neuropsychopharmacology - Depression Research Unit, Department of Psychiatry, Veterans Administration Hospital, Hospital of the University of Pennsylvania, 1978-1979.
Certifications
Diplomate, National Board of Medical Examiners, 1975.
Diplomate, American Board of Psychiatry and Neurology, 1979.
Permanent linkDiplomate, National Board of Medical Examiners, 1975.
Diplomate, American Board of Psychiatry and Neurology, 1979.
Description of Research Expertise
1977-present1) Psychopharmacology of Affective Disorders
2) Antidepressant Drug Development
3) Investigational Clinical Trials
4) Bipolar Affective Disorders
5) Treatment-resistant Affective Disorders
6) Brain Imaging Studies
7) Psychoneuroendocrinology of Affective disorders
8) Psychoimmunovirology
9) Clinical Pharmacokinetics
10)Complementary & Alternative Medicine
Selected Publications
Amsterdam, J.D. Brunswick, D.J.: Antidepressant monotherapy for bipolar type II major depression. Bipolar Disorders 5: 388-395, 2003.Brunswick, D.J., Amsterdam, J.D., Mozley, P.D., Newberg, A.: Greater availability of brain dopamine transporters in major depression shown by[99mTc]TRODAT-1 SPECT imaging. American Journal of Psychiatry 160: 1836, 2003.
Brunswick, D.J., Goodman, D.B., O’Reardon, J.P., Chopra, M., Amsterdam, J. D.: Pindolol does not sugment cortisol and prolactin response to paroxetine in healthy subjects. Progress in Neuro-Psychopharmacology & Biological Psychiatry 28: 477, 2004.
Amsterdam, J.D., Shults, J., Brunswick, D.J., Hundert, M.: Short-term fluoxetine monotherapy for bipolar type II or bipolar NOS major depression – Low manic switch rate. Bipolar Disorders 6: 75-81, 2004.
Quitkin, F., Petkova, E., McGrath, P., Nunes, E., Taylor, B., Beasley, C., Stewert, J., Amsterdam, J.D., Fava, M., Reimherr, F., Fawcwtt, J., Klein, D.: When should a trial of fluoxetine for major depression be declared failed? American Journal of Psychiatry 160: 734-740, 2003.
Amsterdam, J.D.: A double-blind, placebo-controlled clinical trial of the safety and efficacy of the selegiline transdermal system without dietary restrictions in patients with major depression. Journal of Clinical Psychiatry 64: 208-214, 2003.
Hornig-Rohan, M., Amsterdam, J.D.: Prolactin, growth hormone, insulin, glucagons, and parathyroid hormone: Psychobiological & Clinical Implications. Psychoneuroendocinology for the Clinician. Wolkowitz, O.M. & Rothschild, A. (eds.). American Psychiatric Press, Inc., Washington, D.C. Page: 107-138, 2002.
Hornig-Rohan, M., Amsterdam, J.: Venlafaxine versus stimulant therapy in patients with dual diagnoses of attention deficit disorder and depression. Progress in Neuro- Psychopharmacology & Biological Psychiatry 26: 585-589, 2002.
Brunswick, D.J., Amsterdam, J.D., Fawcett, J., Quitkin, F.M., Reimherr, F.W., Rosenbaum, J.F., Beasley, C.M., Jr.: Fluoxetine and norfluoxetine plasma concentrations during relapse-prevention treatment. Journal of Affective Disorders 68: 243-249, 2002.
Bodkin, A.J., Amsterdam, J.D.: A double-blind, placebo-controlled, parallel group study of transdermal selegiline (a selective monoamine oxidase B inhibitor) in outpatients with major depression. American Journal of Psychiatry 159: 1869-1875, 2002.
