Penn Comprehensive Neuroscience Center

Faculty Members
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Michael Edward Thase, MD

Professor of Psychiatry
Physician 1, Philadelphia VA Medical Center
Department: Psychiatry

Contact information
Department of Psychiatry
Mood and Anxiety Disorders Treatment and Research Program
3535 Market Street
Suite 670
Philadelphia, PA 19104-3309
Office: 215-746-6680
Fax: 215-573-0759
Education:
B.A. (Psychology)
Wright State University, Dayton, OH, 1975.
M.D. (Medicine)
Ohio State University College of Medicine, Columbus, OH, 1979.
Post-Graduate Training
Internship in Medicine and Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA, 1979-1980.
General Psychiatry Residency, Western Psychiatric Institute and Clinic, Pittsburgh, PA, 1980-1982.
Postdoctoral Fellowship in Clinical Research, Western Psychiatric Institute and Clinic, Pittsburgh, PA, 1982-1984.
Chief Resident in Affective Disorders, Western Psychiatric Institute and Clinic, Pittsburgh, PA, 1982-1983.
Certifications
American Board of Psychiatry and Neurology, 1984.
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Selected Publications

Nierenberg AA., Fava M., Trivedi MH., Wisniewski SR., Thase ME., McGrath PJ., Alpert JE., Warden D., Luther JF., Niederehe G., Lebowitz B., Shores-Wilson K., Rush AJ.: A comparison of lithium and T(3) augmentation following two failed medication treatments for depression: a STAR*D report.[see comment] American Journal of Psychiatry 163(9): 1519-30; quiz 1665, Sep 2006.

Brown C., Battista DR., Sereika SM., Bruehlman RD., Dunbar-Jacob J., Thase ME.: How can you improve antidepressant adherence? Journal of Family Practice 56(5): 356-63, May 2007.

Rush AJ., Kraemer HC., Sackeim HA., Fava M., Trivedi MH., Frank E., Ninan PT., Thase ME., Gelenberg AJ., Kupfer DJ., Regier DA., Rosenbaum JF., Ray O., Schatzberg AF., ACNP Task Force.: Report by the ACNP Task Force on response and remission in major depressive disorder. [Review] [138 refs] Neuropsychopharmacology 31(9): 1841-53, Sep 2006.

Najavits LM., Harned MS., Gallop RJ., Butler SF., Barber JP., Thase ME., Crits-Christoph P.: Six-month treatment outcomes of cocaine-dependent patients with and without PTSD in a multisite national trial. Journal of Studies on Alcohol 68(3): 353-61, May 2007.

Thase ME., Friedman ES., Biggs MM., Wisniewski SR., Trivedi MH., Luther JF., Fava M., Nierenberg AA., McGrath PJ., Warden D., Niederehe G., Hollon SD., Rush AJ.: Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report. American Journal of Psychiatry 164(5): 739-52, May 2007.

Wisniewski SR., Fava M., Trivedi MH., Thase ME., Warden D., Niederehe G., Friedman ES., Biggs MM., Sackeim HA., Shores-Wilson K., McGrath PJ., Lavori PW., Miyahara S., Rush AJ.: Acceptability of second-step treatments to depressed outpatients: a STAR*D report. American Journal of Psychiatry 164(5): 753-60, May 2007.

Miklowitz DJ., Otto MW., Frank E., Reilly-Harrington NA., Wisniewski SR., Kogan JN., Nierenberg AA., Calabrese JR., Marangell LB., Gyulai L., Araga M., Gonzalez JM., Shirley ER., Thase ME., Sachs GS.: Psychosocial treatments for bipolar depression: a 1-year randomized trial from the Systematic Treatment Enhancement Program. Archives of General Psychiatry 64(4): 419-26, Apr 2007.

Nemeroff CB., Thase ME., EPIC 014 Study Group.: A double-blind, placebo-controlled comparison of venlafaxine and fluoxetine treatment in depressed outpatients. Journal of Psychiatric Research 41(3-4): 351-9, Apr-Jun 2007.

Sachs GS., Nierenberg AA., Calabrese JR., Marangell LB., Wisniewski SR., Gyulai L., Friedman ES., Bowden CL., Fossey MD., Ostacher MJ., Ketter TA., Patel J., Hauser P., Rapport D., Martinez JM., Allen MH., Miklowitz DJ., Otto MW., Dennehy EB., Thase ME.: Effectiveness of adjunctive antidepressant treatment for bipolar depression.[see comment] New England Journal of Medicine 356(17): 1711-22, Apr 26 2007.

Stewart JW., Thase ME.: Treating DSM-IV depression with atypical features. [Review] [16 refs] Journal of Clinical Psychiatry 68(4): e10, Apr 2007.

Grant MM., Friedman ES., Haskett RF., Riso LP., Thase ME.: Urinary free cortisol levels among depressed men and women: differential relationships to age and symptom severity? Archives of Women's Mental Health 10(2): 73-8, 2007.

Rapaport MH., Thase ME.: Translating the evidence on atypical depression into clinical practice. [Review] [29 refs] Journal of Clinical Psychiatry 68(4): e11, Apr 2007.

Thase ME.: Bipolar depression: diagnostic and treatment considerations. [Review] [108 refs] Development & Psychopathology 18(4): 1213-30, 2006.

Siegle GJ., Thompson W., Carter CS., Steinhauer SR., Thase ME.: Increased amygdala and decreased dorsolateral prefrontal BOLD responses in unipolar depression: related and independent features. Biological Psychiatry 61(2): 198-209, Jan 15 2007.

Thase ME., Corya SA., Osuntokun O., Case M., Henley DB., Sanger TM., Watson SB., Dube S.: A randomized, double-blind comparison of olanzapine/fluoxetine combination, olanzapine, and fluoxetine in treatment-resistant major depressive disorder. Journal of Clinical Psychiatry 68(2): 224-36, Feb 2007.

Rush AJ., Trivedi MH., Wisniewski SR., Nierenberg AA., Stewart JW., Warden D., Niederehe G., Thase ME., Lavori PW., Lebowitz BD., McGrath PJ., Rosenbaum JF., Sackeim HA., Kupfer DJ., Luther J., Fava M.: Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. American Journal of Psychiatry 163(11): 1905-17, Nov 2006.

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Last updated: 06/21/2010
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