Dejian Ren
Assistant Professor of Biology
Department: Biology
Graduate Group Affiliations
Contact information
204H Lynch Laboratories
Department of Biology
University of Pennsylvania
Philadelphia, PA 19104
Department of Biology
University of Pennsylvania
Philadelphia, PA 19104
Email:
dren@sas.upenn.edu
dren@sas.upenn.edu
Education:
Ph.D. (Physiology and Biophysics)
SUNY at Buffalo, 1997.
Permanent linkPh.D. (Physiology and Biophysics)
SUNY at Buffalo, 1997.
Selected Publications
Ren D.: Sperm and the proton channel. N Engl J Med 362: 1934-5, 2010.Lu B, Zhang Q, Wang H, Wang Y, Nakayama M, Ren D.: Extracellular Calcium Controls Background Current and Neuronal Excitability via an UNC79-UNC80-NALCN Cation Channel Complex. Neuron 68: 488-499, 2010.
Xia, J. and Ren, D. : Egg coat proteins activate Ca2+ entry into mouse sperm via CatSper channels. Biol. Reprod. Page: (in press), 2009.
Lu, B.*, Su, Y.*, Das, S., Wang, H., Wang, Y., Liu, J., and Ren, D. : Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80. Nature 457: 741-744 (Epub 2008 Dec 17), 2009.
Lu, B., Su, Y., Das, S., Liu, J., Xia, J. and Ren, D. : The neuronal channel NALCN contributes resting sodium permeability and is required for normal respiratory rhythm. Cell 129: 371-383, 2007.
Liu, J., Xia, J., Cho, K-H., Clapham, D.E. and Ren, D. : CatSperĪ², a novel transmembrane protein in the CatSper channel complex. J. Biol. Chem. 282: 18945-18952 2007.
Xia, J., Reigada, D., Mitchell, C.H. and Ren, D. : CATSPER channel-mediated Ca2+ entry into mouse sperm triggers a tail-to-head propagation. Biol. Reprod. 77: 551-559, 2007.
Ren, D.*, Navarro, B.*, Xu, H.*, Yue, L.*, Shi, Q. and Clapham, D.E. : A prokaryotic voltage-gated sodium channel. Science 294: 2372-2375 2001.
Ren, D., Navarro, B., Perez, G., Jackson, A.C., Hsu, S., Shi, Q., Tilly, J.L. and Clapham, D.E.: A sperm ion channel required for sperm motility and male fertility. Nature 413: 603-609 2001.