Penn Transplant Institute

Transplant Faculty

Thomas P. Cappola, M.D., Sc.M.

faculty photo
Associate Professor of Medicine
Attending, Hospital of the University of Pennsylvania, Heart Failure and Transplantation Service
Director, Heart Failure Clinical Research, Penn Cardiovascular Institute
Member, Penn Cardiovascular Institute
Member, Institute for Diabetes, Obesity, and Metabolism
Member, Institute for Translational Medicine and Therapeutics
Member, Penn Genome Frontiers Institute
Chief, Division of Cardiovascular Medicine, University of Pennsylvania Perelman School of Medicine
Department: Medicine

Contact information
Division of Cardiovascular Medicine
9035 West Gates
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-3140
Fax: 215-349-8017
Lab: 215-573-4717
Graduate Group Affiliations
Education:
A.B. (Chemistry)
Princeton University, 1991.
M.D. (Medicine)
Harvard Medical School, 1995.
Sc.M. (Clinical Investigation )
Johns Hopkins Bloomberg School of Public Health, 2004.
Post-Graduate Training
Intern and Resident, Internal Medicine, Brigham and Women’s Hospital, 1995-1998.
Clinical and Research Fellow, Cardiovascular Disease, Johns Hopkins Hospital, 1998-2002.
Heart Failure and Transplantation Fellow, Johns Hopkins Hospital, 2000-2001.
Research Fellow, National Heart, Lung, and Blood Institute Program in Genomic Applications, Johns Hopkins Medical Institutions, 2001-2002.
Honorary Senior Visiting Fellow, University of Cambridge, UK, 2013-2014.
Certifications
American Board of Internal Medicine Certification in Internal Medicine , 1998.
American Board of Internal Medicine Certification in Cardiovascular Medicine, 2002.
American Board of Internal Medicine Certification in Advanced Heart Failure and Transplantation, 2010.
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Selected Publications

Liu Y, Morley M, Brandimarto J, Hannenhalli S, Hu Y, Ashley EA, Tang WH, Moravec CS, Margulies KB, Cappola TP, Li M; for the MAGNet consortium: RNA-Seq identifies novel myocardial gene expression signatures of heart failure. Genomics 105(2): 83-89, Feb 2015.

Tampakakis E, Leary PJ, Selby VN, De Marco T, Cappola TP, Felker GM, Russell SD, Kasper EK, Tedford RJ : The diastolic pulmonary gradient does not predict survival in patients with pulmonary hypertension due to left heart disease. JACC Heart Fail 3(1): 9-16, Jan 2015.

Zamani P, Rawat D, Shiva-Kumar P, Geraci S, Bhuva R, Konda P, Doulias PT, Ischiropoulos H, Townsend RR, Margulies KB, Cappola TP, Poole DC, Chirinos JA : Effect of inorganic nitrate on exercise capacity in heart failure with preserved ejection fraction. Circulation 131(4): 371-80, Jan 2015.

Zhang R, Zhang Y, Zhang J, An T, Huang Y, Guo X, Januzzi JL, Cappola TP, Yin S, Wang Y, Zhou Q, Zou C, Ji S, Lv R : The prognostic value of plasma soluble ST2 in hospitalized Chinese patients with heart failure. PLoS One 9(10): e110976, Oct 2014.

Lu Y, Hannenhalli S, Cappola TP, Putt M: An evaluation of MC Logic and logicFS motivated by a study of the regulation of gene expression in heart failure. Journal of Applied Statistics 41(9): 1956-1975, Sep 2014.

Vorovich E, French B, Ky B, Goldberg L, Fang JC, Sweitzer NK, Cappola TP : Biomarker predictors of cardiac hospitalization in chronic heart failure: a recurrent event analysis. J Card Fail 20(8): 569-76, Aug 2014.

Margulies KB, Anstrom K, Hernandez AF, Redfield MM, Shah MR, Braunwald E, Cappola, TP: GLP-1 agonist therapy for advanced heart failure with reduced ejection fraction: design and rationale for the functional impact of GLP-1 for heart failure treatment (FIGHT) study Circ Heart Fail 7(4): 673-9, Jul 2014.

Basuray A, French B, Ky B, Sweitzer N, Vorovich E, Cappola TP, Fang JC: Heart failure with recovered ejection fraction: clinical description, biomarkers, and outcomes Circulation 129(23): 2380-7, Jun 2014.

Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Elizabeth J., Rossin EJ, Morley M, Cappola TP, Olsen JV, Lage K, Schwartz PJ, Kääb S, Chakravarti A, Ackerman MJ, Pfeufer A, de Bakker P, Newton-Cheh C: Genetic association study of QT interval highlights calcium signaling pathways in myocardial repolarization. Nature Genetics 46(8): 826-36, Jun 2014.

Kapoor A, Sekar RB, Hansen NF, Fox-Talbot K, Morley M, Pihur V, Chatterjee S, Brandimarto J, Pfuefer A, Mullikin J, Ross M, Green E, Bentley D, Tomaselli GF, Cappola TP, Arking DE, Halushka MK, Chakravarti A: An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval Am J Hum Genet 94(6), May 2014.

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Last updated: 03/11/2015
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