Penn Transplant Institute

Transplant Faculty

J. Eduardo Rame, M.D., M.Phil

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Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Attending, Cardiac Catherization Laboratory, Hospital of the University of Pennsylvania
Attending, Heart Failure, Mechanical Assist, and Cardiac Transplantation Program, Hospital of the University of Pennsylvania
Attending, Pulmonary Hypertension Program, Hospital of the University of Pennsylvania
Medical Director, Mechanical Circulatory Support Program, Hospital of the University of Pennsylvania
Interim Director, Pulmonary Hypertension Program - Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Penn Medicine
Heart Failure, Mechanical Assist and Cardiac Transplant Center
Hospital of the University of Pennsylvania
2 East, Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-615-7949
Fax: 215-349-5603
Education:
B.S., M.S. (Molecular Biophysics and Biochemistry)
Yale College, 1990.
M.Phil (Statistics/Health Services Research)
Oxford University , 1996.
M.D. (Medicine)
Harvard Medical School , 1997.
Post-Graduate Training
Intern in Internal Medicine, University of Texas Southwestern, 1997-1998.
Resident in Internal Medicine, University of Texas Southwestern, 1998-2000.
Fellow in Cardiovascular Genomics, University of Texas Southwestern, 2000-2002.
Fellow in Cardiology, Johns Hopkins University School of Medicine and Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health , 2002-2004.
Fellow in Heart Failure/Heart Transplant, Johns Hopkins Hospital, 2004-2005.
Certifications
American Board of Internal Medicine (Internal Medicine), 2000.
American Board of Internal Medicine (Cardiovascular Disease), 2005.
American Board of Internal Medicine (Certification in Advanced Heart Failure and Cardiac Transplantation patients), 2010.
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Selected Publications

Ascheim DD, Gelijns AC, Goldstein D, Moye LA, Smedira N, Lee S, Klodell CT, Szady A, Parides MK, Jeffries NO, Skerrett D, Taylor DA, Rame JE, Milano C, Rogers JG, Lynch J, Dewey T, Eichhorn E, Sun B, Feldman D, Simari R, O'Gara PT, Taddei-Peters WC, Miller MA, Naka Y, Bagiella E, Rose EA, Woo YJ: Mesenchymal precursor cells as adjunctive therapy in recipients of contemporary left ventricular assist devices. Circulation 129(22): 2287-96, Jun 2014 Notes: Epub 2014 Mar 28.

Birati EY, Kirkpatrick JN, Rame JE, Bala R, Margulies KB.: Dynamic left ventricular assist device inflow obstruction. Circ Heart Fail 7(1): 225-6, Jan 2014

Santangeli P, Muser D, Zado ES, Magnani S, Khetpal S, Hutchinson MD, Supple G, Frankel DS, Garcia FC, Bala R, Riley MP, Lin D, Rame JE, Schaller R, Dixit S, Marchlinski FE, Callans DJ. : Acute Hemodynamic Decompensation during Catheter Ablation of Scar-Related VT: Incidence, Predictors and Impact on Mortality. Circ Arrhythm Electrophysiol Dec 2014.

Lee R*, Xu B*, Rame JE*, Felkin LE, Barton P, Dries DL: Regulated inositol-requiring protein 1-dependent decay as a mechanism of corin RNA and protein deficiency in advanced human systolic heart failure. J Am Heart Assoc. 3(6), Dec 2014.

Edo Y. Birati, Ylenia Quiaoit, Joyce Wald, James N. Kirkpatrick, Lee R. Goldberg, Pavan Atluri, Kenneth B. Margulies, J. Eduardo Rame: Ventricular Assist Device Thrombosis: A Wide Spectrum of Clinical Presentation. Journal of Heart and Lung Transplantation Dec 2014 Notes: Publication stage: In Press Accepted Manuscript The Journal of Heart and Lung Transplantation Published online: December 23, 2014

Nathaniel Snyder; Kenneth C Bedi; Ali Javaheri; Clementina Mesaros; Ken Margulies; Ian Blair; J E Rame : Short Chain Acyl-CoA Intermediates in the Failing Heart: Further Evidence of an Energy Starved State Circulation Nov 2014.

Johnson NJ, Acker M, Hsu CH, Desai N, Vallabhajosyula P, Lazar S, Horak J, Wald J, McCarthy F, Rame E, Gray K, Perman SM, Becker L, Cowie D, Grossestreuer A, Smith T, Gaieski DF: Extracorporeal life support as rescue strategy for out-of-hospital and emergency department cardiac arrest. Resuscitation 85(11), Nov 2014.

John R, Aaronson KD, Pae WE, Acker MA, Hathaway DR, Najarian KB, Slaughter MS; HeartWare Bridge to Transplant ADVANCE Trial Investigators: Drive-line infections and sepsis in patients receiving the HVAD system as a left ventricular assist device. J Heart Lung Transplant 33(10): 1066-73, Oct 2014.

Johnson NJ, Acker M, Hsu CH, Desai N, Vallabhajosyula P, Lazar S, Horak J, Wald J, McCarthy F, Rame E, Gray K, Perman SM, Becker L, Cowie D, Grossestreuer A, Smith T, Gaieski DF: Extracorporeal life support as rescue strategy for out-of-hospital and emergency department cardiac arrest. Resuscitation S0300-9572(14): 00730-8, Sept 2014 Notes: [Epub ahead of print]

Rame JE, Vaidya A: Disease Progression in Pulmonary Arterial Hypertension: Refining the Phenotype With a Prognostic Biomarker Profile From Collagen. JACC Heart Fail. 2(4): 422-4, August 2014 Notes: Epub 2014 Jul 9

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Last updated: 01/21/2015
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