Penn Transplant Institute

Transplant Faculty

J. Eduardo Rame, M.D., M.Phil

faculty photo
Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Attending, Cardiac Catherization Laboratory, Hospital of the University of Pennsylvania
Attending, Heart Failure, Mechanical Assist, and Cardiac Transplantation Program, Hospital of the University of Pennsylvania
Attending, Pulmonary Hypertension Program, Hospital of the University of Pennsylvania
Medical Director, Mechanical Circulatory Support Program, Hospital of the University of Pennsylvania
Member, Cardiovascular Institute, University of Pennsylvania
Interim Director, Pulmonary Hypertension Program - Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Penn Medicine
Heart Failure, Mechanical Assist and Cardiac Transplant Center
Hospital of the University of Pennsylvania
2 East, Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-615-7949
Fax: 215-349-5603
Education:
B.S., M.S. (Molecular Biophysics and Biochemistry)
Yale College, 1990.
M.Phil (Statistics/Health Services Research)
Oxford University , 1996.
M.D. (Medicine)
Harvard Medical School , 1997.
Post-Graduate Training
Intern in Internal Medicine, University of Texas Southwestern, 1997-1998.
Resident in Internal Medicine, University of Texas Southwestern, 1998-2000.
Fellow in Cardiovascular Genomics, University of Texas Southwestern, 2000-2002.
Fellow in Cardiology, Johns Hopkins University School of Medicine and Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health , 2002-2004.
Fellow in Heart Failure/Heart Transplant, Johns Hopkins Hospital, 2004-2005.
Certifications
American Board of Internal Medicine (Internal Medicine), 2000.
American Board of Internal Medicine (Cardiovascular Disease), 2005.
American Board of Internal Medicine (Certification in Advanced Heart Failure and Cardiac Transplantation patients), 2010.
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Selected Publications

Edo Y. Birati, Ylenia Quiaoit, Joyce Wald, James N. Kirkpatrick, Lee R. Goldberg, Pavan Atluri, Kenneth B. Margulies, J. Eduardo Rame: Ventricular Assist Device Thrombosis: A Wide Spectrum of Clinical Presentation. The Journal of Heart and Lung Transplantation 34(4): 613, April 2015 Notes: Published online: December 23, 2014.

Burkhoff D, Maurer MS, Joseph SM, Rogers JG, Birati EY, Rame JE, Shah SJ: Left atrial decompression pump for severe heart failure with preserved ejection fraction: theoretical and clinical considerations. JACC Heart Fail 3(4): 275-283, April 2015.

Birati EY, Rame JE: Diagnosis and Management of LVAD Thrombosis. Curr Treat Options Cardiovasc Med 17(2): 361, February 2015.

James N Kirkpatrick, Georg Wieselthaler, Martin Strueber, Martin G St John Sutton, J Eduardo Rame : Ventricular assist devices for treatment of acute heart failure and chronic heart failure. Heart EPUB ahead of print 2015.

Jeffrey J Teuteberg, MD, Mark S Slaughter, MD, Joseph G Rogers, MD, Edwin C McGee, MD, Francis D Pagani, MD, PhD, Robert Gordon, MD, Eduardo Rame, MD, Michael Acker, MD, Robert L Kormos, MD, Christopher Salerno, MD, Thomas P Schleeter, MD, Daniel J Goldstein, MD, Julia Shin, MD, Randall C Starling, MD MPH, Thomas Wozniak, MD, Adnan S Malik, MD, Scott Silvestry, MD, Gregory A Ewald, MD, Ulrich P Jorde, MD, Yoshifumi Naka, MD, PhD, Emma Birks, MD, PhD, Kevin B Najarian, MS, David R Hathaway, MD and Keith D Aaronson, MD, MS : The HVAD Left Ventricular Assist Device: Risk Factors for Neurologic Events and Preventative Mitigation Strategies. JACC Heart Failure EPUB Ahead of Print 2015.

Ascheim DD, Gelijns AC, Goldstein D, Moye LA, Smedira N, Lee S, Klodell CT, Szady A, Parides MK, Jeffries NO, Skerrett D, Taylor DA, Rame JE, Milano C, Rogers JG, Lynch J, Dewey T, Eichhorn E, Sun B, Feldman D, Simari R, O'Gara PT, Taddei-Peters WC, Miller MA, Naka Y, Bagiella E, Rose EA, Woo YJ: Mesenchymal precursor cells as adjunctive therapy in recipients of contemporary left ventricular assist devices. Circulation 129(22): 2287-96, Jun 2014 Notes: Epub 2014 Mar 28.

Birati EY, Kirkpatrick JN, Rame JE, Bala R, Margulies KB.: Dynamic left ventricular assist device inflow obstruction. Circ Heart Fail 7(1): 225-6, Jan 2014

Santangeli P, Muser D, Zado ES, Magnani S, Khetpal S, Hutchinson MD, Supple G, Frankel DS, Garcia FC, Bala R, Riley MP, Lin D, Rame JE, Schaller R, Dixit S, Marchlinski FE, Callans DJ. : Acute Hemodynamic Decompensation during Catheter Ablation of Scar-Related VT: Incidence, Predictors and Impact on Mortality. Circ Arrhythm Electrophysiol Dec 2014.

Lee R*, Xu B*, Rame JE*, Felkin LE, Barton P, Dries DL: Regulated inositol-requiring protein 1-dependent decay as a mechanism of corin RNA and protein deficiency in advanced human systolic heart failure. J Am Heart Assoc. 3(6), Dec 2014.

Edo Y. Birati, Ylenia Quiaoit, Joyce Wald, James N. Kirkpatrick, Lee R. Goldberg, Pavan Atluri, Kenneth B. Margulies, J. Eduardo Rame: Ventricular Assist Device Thrombosis: A Wide Spectrum of Clinical Presentation. Journal of Heart and Lung Transplantation Dec 2014 Notes: Publication stage: In Press Accepted Manuscript The Journal of Heart and Lung Transplantation Published online: December 23, 2014

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Last updated: 06/21/2015
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