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J. Eduardo Rame, MD, MPhil

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Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Attending, Cardiac Catherization Laboratory, Hospital of the University of Pennsylvania
Attending, Heart Failure, Mechanical Assist, and Cardiac Transplantation Program, Hospital of the University of Pennsylvania
Attending, Pulmonary Hypertension Program, Hospital of the University of Pennsylvania
Medical Director, Mechanical Circulatory Support Program, Hospital of the University of Pennsylvania
Member, Cardiovascular Institute, University of Pennsylvania
Department: Medicine

Contact information
Penn Medicine
Heart Failure, Mechanical Assist and Cardiac Transplant Center
Hospital of the University of Pennsylvania
2 East, Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-615-7949
Fax: 215-349-5603
Education:
B.S., M.S. (Molecular Biophysics and Biochemistry)
Yale College, 1990.
M.Phil (Statistics/Health Services Research)
Oxford University , 1996.
M.D. (Medicine)
Harvard Medical School , 1997.
Post-Graduate Training
Intern in Internal Medicine, University of Texas Southwestern, 1997-1998.
Resident in Internal Medicine, University of Texas Southwestern, 1998-2000.
Fellow in Cardiovascular Genomics, University of Texas Southwestern, 2000-2002.
Fellow in Cardiology, Johns Hopkins University School of Medicine and Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health , 2002-2004.
Fellow in Heart Failure/Heart Transplant, Johns Hopkins Hospital, 2004-2005.
Certifications
American Board of Internal Medicine (Internal Medicine), 2000.
American Board of Internal Medicine (Cardiovascular Disease), 2005.
American Board of Internal Medicine (Certification in Advanced Heart Failure and Cardiac Transplantation patients), 2010.
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Selected Publications

Bedi KC Jr, Snyder NW, Brandimarto J, Aziz M, Mesaros C, Worth AJ, Wang LL, Javaheri A, Blair IA, Margulies KB, Rame JE: Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure. Circulation 133(8): 706-16, February 2016 Notes: Epub 2016 Jan 27.

Birati EY, Mathelier H, Molina M, Hanff TC, Mazurek JA, Atluri P, Acker MA, Rame JE, Margulies KB, Goldberg LR, Jessup M: Comparison of Causes of Death After Heart Transplantation in Patients With Left Ventricular Ejection Fractions ‚ȧ35% Versus >35. The American Journal of Cardiology S0002-9149(16): 30150-3, January 2016.

Burkhoff D, Maurer MS, Joseph S, Rogers JG, Birati Eo, Rame JE, Shah SJ: Reply: Is Pump the Answer to Heart Failure With Preserved Ejection Fraction? JACC Heart Fail 4(1): 93, January 2016.

Rame JE: Metabolic Staging in Human Heart Failure: Circulating Acylcarnitines and the Failing Heart's Energetic Signature. J Am Coll cardiol 67(3): 300-2, January 2016.

Stewart GC, Kittleson MM, Cowger JA, Johnson FL, Patel CB, Mountis MM, Patel PC, Rame JE, Testani J, Guglin ME, Teuteberg JJ, Stevenson LW: Who wants a left ventricular assist device for ambulatory heart failure? Early insights from the MEDAMACS screening pilot. J Heart Lung Transplant 34(12): 1630-3, December 2015 Notes: Epub 2015 Aug 4.

McCarthy FH, Kobrin D, Rame JE, Groeneveld PW, McDermott KM, Atluri P, Acker MA, Desai ND: Increasing Frequency of Left Ventricular Assist Device Exchanges in the United States. Annals of Thoracic Surgery 100(5): 1660-4; discussion 1665, November 2015 Notes: Epub 2015 Jul 21.

Bermudez CA, Rame JE: Reversible but risky: Pulmonary hypertension in advanced heart failure is the Achilles' heel of cardiac transplantation. J Thorac Cardiovasc Surg 150(5): 1362-3, November 2015 Notes: Epub 2015 Aug 6.

Rame JE, Birati EY: HeartWare Left Ventricular Assist Device Pump Thrombosis: A Shift Away From Ramp. JACC Heart Fail 3(11): 857-9, November 2015 Notes: Epub 2015 Oct 7.

Teuteberg JJ, MD, Slaughter MS, Rogers JG, McGee EC, Pagani FD, Gordon R, Rame E, Acker M, Kormos RL, Salerno C, Schleeter TP, Goldstein DJ, Shin J, Starling RC, Wozniak T, Malik AS, Silvestry S, Ewald GA, Jorde UP, Naka Y, Birks E, Najarian KB, Hathaway DR, Aaronson KD : The HVAD Left Ventricular Assist Device: Risk Factors for Neurologic Events and Preventative Mitigation Strategies. JACC Heart Failure. (eds.). 3(10): 818-28, October 2015.

E. Wilson Grandin, Gregory S. Troutman, Payman Zamani, Jeremy A. Mazurek, Ryan J. Tedford, Anjali Vaidya, Julio Chirinos, Pavan Atluri, Ken Margulies, Paul Forfia, J. Eduardo Rame : Indices of Pulsatile and Resistive Afterload and Load-Dependent and Load-Independent Right Ventricular Dysfunction in HFrEF. J. Cardiac Failure September 2015 Notes: Presented at the Heart Failure Society of America (HFSA).

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Last updated: 03/24/2016
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