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Clara Franzini-Armstrong

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Emeritus Professor of Cell and Developmental Biology
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Department: Cell and Developmental Biology
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46 Contact information
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B43 Anatomy/Chemistry
Philadelphia, PA 19104/6058
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2e Office: 215-898-3345
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18 Publications
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13 Education:
21 a Ph.D. 20 (Biological Sciences) c
32 University of Pisa, Italy, 1960.
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1f Post-Graduate Training
24 52 Perfezionanda, Scuola Normale Superiore, Pisa. Italy, 1960-1961.
24 66 Post-Doctoral Fellow, Biological Laboratories (advisor: Keith R. Porter), 1961-1963.
24 5b Research Assistant, NIH, NIAMD (advisor: Richard J. Podolsky), 1963-1964.
24 6e Hon. Research Assistant, University College, London (advisor: Andrew F. Huxley), 1964-1966.
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Selected Publications

10f Franzini-Armstrong C.: An updated view of the structural basis for dihydropyridine receptors-ryanodine receptors direct molecular interaction in skeletal muscle. Eur J Transl Myol. 34(1), Mar 2024.

10d Franzini-Armstrong Clara: Correction: The relationship between form and function throughout the history of excitation-contraction coupling. The Journal of general physiology 150(2): 369, Feb 2018.

105 Franzini-Armstrong Clara: The relationship between form and function throughout the history of excitation-contraction coupling. The Journal of general physiology 150(2): 189-210, Feb 2018.

161 Lee In-Gyun, Olenick Mara A, Boczkowska Malgorzata, Franzini-Armstrong Clara, Holzbaur Erika L F, Dominguez Roberto: A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity. Nature communications 9(1): 986, 03 2018.

1fb Lavorato Manuela, Iyer V Ramesh, Dewight Williams, Cupo Ryan R, Debattisti Valentina, Gomez Ludovic, De la Fuente Sergio, Zhao Yan-Ting, Valdivia Héctor H, Hajnóczky György, Franzini-Armstrong Clara: Increased mitochondrial nanotunneling activity, induced by calcium imbalance, affects intermitochondrial matrix exchanges. Proceedings of the National Academy of Sciences of the United States of America 114(5): E849-E858, Jan 2017.

1c3 Linsley Jeremy W, Hsu I-Uen, Groom Linda, Yarotskyy Viktor, Lavorato Manuela, Horstick Eric J, Linsley Drew, Wang Wenjia, Franzini-Armstrong Clara, Dirksen Robert T, Kuwada John Y: Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3. Proceedings of the National Academy of Sciences of the United States of America 114(2): E228-E236, Jan 2017.

190 Manno Carlo, Figueroa Lourdes C, Gillespie Dirk, Fitts Robert, Kang ChulHee, Franzini-Armstrong Clara, Rios Eduardo: Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle. Proceedings of the National Academy of Sciences of the United States of America 114(4): E638-E647, Jan 2017.

154 Lavorato Manuela, Gupta Pawan K, Hopkins Philip M, Franzini-Armstrong Clara: Skeletal Muscle Microalterations in Patients Carrying Malignant Hyperthermia-Related Mutations of the e-c Coupling Machinery. European journal of translational myology 26(4): 6105, Sep 2016.

cd Franzini-Armstrong Clara: Can the Arrangement of RyR2 in Cardiac Muscle Be Predicted? Biophysical journal 110(12): 2563-5, Jun 2016.

107 Perni Stefano, Close Matthew, Franzini-Armstrong Clara: Design Principles of Reptilian Muscles: Calcium Cycling Strategies. Anatomical record (Hoboken, N.J. : 2007) 299(3): 352-60, Mar 2016.

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