Perelman School of Medicine at the University of Pennsylvania

Penn Institute for Immunology

Christina Twyman-Saint Victor

faculty photo
Assistant Professor of Medicine
Department: Medicine
Graduate Group Affiliations

Contact information
421 Curie Boulevard
906 Biomedical Research Building II/III
Philadelphia, PA 19104
Office: 215-349-8222
Fax: 215.349.5915
Lab: 215-573-1859
Education:
BS (Biology)
Duke University, 2002.
MD
Johns Hopkins Hospital, 2007.
MS (Translational Research)
University of Pennsylvania , 2016.
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Description of Clinical Expertise

General gastroenterology and endoscopy (e.g. EGD and colonoscopy)

Selected Publications

Benci JL, Xu B, Qiu Y, Wu TJ, Dada H, Twyman-Saint Victor C, Cucolo L, Lee DS, Pauken KE, Huang AC, Gangadhar TC, Amaravadi RK, Schuchter LM, Feldman MD, Ishwaran H, Vonderheide RH, Maity A, Wherry EJ, Minn AJ.: Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade. Cell 167(6), Dec 2016.

Tétreault MP, Weinblatt D, Ciolino JD, Klein-Szanto AJ, Sackey BK, Twyman-Saint Victor C, Karakasheva T, Teal V, Katz JP.: Esophageal Expression of Active IκB Kinase-β in Mice Up-Regulates Tumor Necrosis Factor and Granulocyte-Macrophage Colony-Stimulating Factor, Promoting Inflammation and Angiogenesis. Gastroenterology 150(7): 1609-1619, Jun 2016.

Twyman-Saint Victor C*, Rech AJ*, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ: Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature 520(7547): 373-7, Apr 2015.

Boelens MC, Wu TJ, Nabet BY, Xu B, Qiu Y, Yoon T, Azzam DJ, Twyman-Saint Victor C, Wiemann BZ, Ishwaran H, Ter Brugge PJ, Jonkers J, Slingerland J, Minn AJ.: Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell 159(3): 499-513, Oct 2014.

Babyatsky M, Lin J, Yio X, Chen A, Zhang JY, Zheng Y, Twyman C, Bao X, Schwartz M, Thung S, Lawrence Werther J, Itzkowitz S.: Trefoil factor-3 expression in human colon cancer liver metastasis. Clinical & Experimental Metastasis 26(2): 143-51, Nov 2009.

Zen Q, Batchvarova M, Twyman CA, Eyler CE, Qiu H, De Castro LM, Telen MJ. : B-CAM/LU expression and the role of B-CAM/LU activation in binding of low- and high-density red cells to laminin in sickle cell disease. Am J Hematol 75(2): 63-72, Feb 2004.

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Last updated: 08/08/2017
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