John R. Stanley

faculty photo
Professor of Dermatology
Department: Dermatology

Contact information
University of Pennsylvania School of Medicine
Department of Dermatology
421 Curie Boulevard, 1008 Biomedical Research Building
Philadelphia, PA 19104
Office: 215-898-0166
Fax: 215-573-2033
Education:
B.A. (Physics)
Cornell University, 1970.
M.D.
Harvard Medical School, 1974.
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Selected Publications

Toumi A, Saleh MA, Yamagami J, Abida O, Kallel M, Masmoudi A, Makni S, Turki H, Hachiya T, Kuroda K, Stanley JR, Masmoudi H, Amagai M: Autoimmune reactivity against precursor form of desmoglein 1 in healthy Tunisians in the area of endemic pemphigus foliaceus. J Dermatol Sci doi: 10.1016/j.jdermsci.2013.02.002. Epub 2012 Feb 19, 70(1): 19-25 April 2013.

Kouno K, Lin C, Schechter N, Siegel D, Yang X, Seykora JT, Stanley JR: Targeted delivery of tumor necrosis factor-related apoptosis-inducing ligand to keratinocytes with a pemphigus monoclonal antibody. J Invest Dermatol February 2013 Notes: Advance online publication 4 April 2013; doi: 10.1038/jid.2013.85.

Lunardon L, Tsai KJ, Propert KJ, Fett N, Stanley JR, Werth VP, Tsai DE, Payne AS: Adjuvant rituximab therapy of pemphigus: A single center experience with 31 patients. Arch Dermatol 148: 1031-1036, 2012.

Yamagami J, Payne AS, Kacir S, Ishii K, Siegel DL, Stanley JR: Homologous regions of heavy chain complementarity determining region 3 (H-CDR3) of pemphigus antibodies cause pathogenicity. J Clin Invest 120: 4111-4117, 2010.

Yamagami J, Kacir S, Ishii K, Payne AS, Siegel DL, Stanley JR: Antibodies to the desmoglein 1 precursor proprotein but not to the mature cell surface protein cloned from individuals without pemphigus. J Immunol 183(9): 5615-5621. doi: 10.4049/jimmunol.0901691. November 2009.

Yamagami J, Kacir S, Ishii K, Payne AS, Siegel DL, Stanley JR: Antibodies to the desmoglein 1 precursor proprotein but not to the mature cell surface protein cloned from individuals without pemphigus. J Immunol 183: 5615-5621, 2009.

Yokouchi M, Saleh MA, Kuroda K, Hachiya T, Stanley JR, Amagai M, Ishii K: Pathogenic epitopes of autoantibodies in pemphigus reside in the amino-terminal adhesive region of desmogleins which are unmasked by proteolytic processing of prosequence. J Invest Dermatol 129: 2156-2166, 2009.

Ishii K, Lin C, Siegel DL, Stanley JR: Isolation of pathogenic monoclonal anti-desmoglein 1 human antibodies by phage display of pemphigus foliaceus autoantibodies. J Invest Dermatol 128: 939-948, 2008.

Payne AS, Siegel DL, Stanley JR: Targeting pemphigus autoantibodies by their heavy chain variable region genes. J Invest Dermatol 127: 1681-1691, 2007.

Heng A, Nwaneshiudu A, Hashimoto T, Amagai M, Stanley JR: Intraepidermal neutrophilic IgA/IgG anti-desmocollin 1 pemphigus. Br J Dermatol 154: 1018-1019, 2006.

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Last updated: 07/26/2013
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