Lubica Rauova

faculty photo
Research Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
The Childrens Hospital of Philadelphia
3615 Civic Center Blv
ARC Room 316F
Philadelphia, PA 1910
Office: 215-426-2883
Lab: 215-590-1971
MD (Medicine)
Masaryk University, Brno, Czech Republic, 1987.
PhD (Internal Medicine)
Commenius University, Bratislava, Slovakia, 1992.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Tutwiler V, Madeeva D, Ahn HS, Andrianova I, Hayes V, Zheng XL, Cines DB, McKenzie SE, Poncz M and Rauova L: Platelet transactivation by monocytes promotes the prothrombotic state in heparin-induced thrombocytopenia. Blood 127(4): 464, Feb 2016.

Cai Z, Yarovoi SV, Zhu Z, Rauova L, Hayes V, Lebedeva T, Liu Q, Poncz M, Arepally G, Cines DB, Greene MI: Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nature Communications 6(8277): 9277, Sep 2015.

Cuker A, Rauova L, Bolgiano D, Matthai WH Jr, Poncz M, Konkle BA.: Atherosclerosis is not a risk factor for anti-platelet factor 4/heparin antibody formation after cardiopulmonary bypass surgery. Thromb Haemost 111(6): 1191-3, Jun 2014.

Litvinov RI, Yarovoi SV, Rauova L, Barsegov V, Sachais BS, Rux AH, Hinds JL, Arepally GM, Cines DB, Weisel JW.: Distinct specificity and single-molecule kinetics characterize the interaction of pathogenic and non-pathogenic antibodies against platelet factor 4-heparin complexes with platelet factor 4. J Biol Chem 288(46): 33060-70, Nov 2013.

Zhi H, Rauova L, Hayes V, Gao C, Boylan B, Newman DK, McKenzie SE, Cooley BC, Poncz M, Newman PJ: Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo. Blood 121(10): 1858-67, Mar 2013.

Sachais BS, Litvinov RI, Yarovoi SV, Rauova L, Hinds JL, Rux AH, Arepally GM, Poncz M, Cuker A, Weisel JW, Cines DB: Dynamic antibody-binding properties in the pathogenesis of HIT. Blood 120(5): 1137-42, Aug 2012.

Rauova Lubica: "Radical" model of thrombosis. Blood 119(8): 1798-9, Feb 2012.

Finley MJ, Rauova L, Alferiev IS, Weisel JW, Levy RJ, Stachelek SJ: Diminished adhesion and activation of platelets and neutrophils with CD47 functionalized blood contacting surfaces. Biomaterials 33(24): 5803-11, Aug 2012.

Rauova L, Hirsch JD, Greene TK, Zhai L, Hayes VM, Kowalska MA, Cines DB, Poncz M: Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia. Blood 116(23): 5021-31, Dec 2010.

Fuentes R, Wang Y, Hirsch J, Wang Ch, Rauova L, Worthen GS, Kowalska MA, Poncz M: Infusion of mature megakaryocytes into mice yields functional platelets. The Journal of clinical investigation 120(11): 3917-22, Nov 2010.

Rauova L, Zhai L, Kowalska MA, Arepally GM, Cines DB, Poncz M: Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications. Blood 107(6): 2346-53, Mar 2006.

Rauova L, Poncz M, McKenzie SE, Reilly MP, Arepally G, Weisel JW, Nagaswami C, Cines DB, Sachais BS: Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia. Blood 105(1): 131-8, Jan 2005.

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Last updated: 09/02/2016
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