Penn Lung Center

Faculty & Staff

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Melpo Christofidou-Solomidou, PhD

Research Associate Professor of Medicine
Director, Pulmonary Morphology Core Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA
Investigator, Center for Excellence in Environmental Toxicology (CEET), University of Pennsylvania
Investigator, Abramson Cancer Center, University of Pennsylvania
Adjunt Faculty, Institute for Environmental Medicine (IFEM), University of Pennsylvania
Department: Medicine

Contact information
University of Pennsylvania, Department of Medicine
Pulmonary, Allergy and Critical Care Division
3615 Civic Center Boulevard
Abramson Research Center, Office Suite 1016C
Philadelphia, PA 19104-6160
Office: (215) 573-9917
Fax: (215) 573-4469
Education:
B.S. (Biology)
State University of New York at Stony Brook, Long Island, New York, 1983.
M.S. (Cell Biology)
Rhenish Friedrich Wilhelm’s University, Bonn, Germany, 1987.
Ph.D. (Cell Biology)
Rhenish Friedrich Wilhelm’s University, Bonn, Germany, 1991.
Post-Graduate Training
Postdoctoral Fellow, Department of Physiology & Cell Biology, Albany Medical College, Albany, NY, 1991-1992.
Postdoctoral Fellow, New York State Affiliate of the American Heart Association, Albany Medical College, Albany, NY, 1992-1993.
Postdoctoral Fellow, Department of Dermatology and Pulmonary, Allergy & Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, PA, 1993-1995.
Postdoctoral Fellow, Pulmonary, Allergy & Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, PA, 1995-1996.
Certifications
IACUC - Advanced Workshop, Rockerfeller Institute, New York, NY. Workshop on Regulatory Issues of Animal Research for Senior IACUC Members., 2004.
Nutrition and Cancer Prevention Research, Practicum, NCI, NIH, Bethesda, MD. Practicum on nutritional approaches to Cancer Research, training on Database applications for nutrition research in cancer and use of NIH facilities for Nutrition Research., 2007.
Patient Oriented Research Certification-University of Pennsylvania, 2007.
Advanced Workshop in Molecular Methodologies - Penn Genome Frontiers, Institute, University of Pennsylvania, Philadelphia , 2008.
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Description of Research Expertise

The theme of Dr. Christofidou-Solomidou's research is pulmonary inflammation and cell adhesion molecule regulation/expression. Projects involve the development of oxidant-induced acute and chronic lung injury animal models for the study of diseases such as ARDS, sepsis, radiation induced pneumonitis/fibrosis, and oxygen toxicity. Specific projects focus on the development of antioxidant methodologies such as immune conjugates for the targeting of anti-oxidant enzymes such as Catalase and Superoxide Dismutase to the pulmonary endothelium using antibodies to endothelial antigens. Recent work extends to the use of dietary alternative antioxidant agents such as curcumin, flaxseed or phenolic compounds in ameliorating acute and chronic oxidative lung disease.
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Last updated: 01/31/2014
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