Paul F. Harron Jr. Lung Center

Paul F. Harron Jr. Lung Center Faculty

faculty photo

Edmund K Moon, MD

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Instructor A in Medicine, University of Pennsylvania, Perelman School of Medicine, Department of Medicine
Department: Medicine

Contact information
3400 Spruce Street
Maloney Building 8th Floor
Philadelphia, PA 19104
Office: (215) 662-3202
Lab: (215) 573-9933
Graduate Group Affiliations
B.A. (Biology & Psychology)
The Johns Hopkins University, 2000.
University of Maryland School of Medicine , 2004.
Post-Graduate Training
Internal Medicine Residency, Temple University, 2004-2007.
Pulmonary, Allergy, & Critical Care Fellowship, University of Pennsylvania, 2007-2011.
Interventional Pulmonary Fellowship, University of Pennsylvania, 2011-2012.
American Board of Internal Medicine, 2007.
American Board of Pulmonary Disease, 2009.
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Selected Publications

Xiaojun Liu, Raghuveer Ranganathan, Shuguang Jiang, Chongyun Fang, Jing Sun, Soyeon Kim, Kheng Newick, Albert Lo, Carl H. June, Yangbing Zhao, Edmund K. Moon: A chimeric switch-receptor targeting PD1 augments the efficacy of second generation CAR T-cells in advanced solid tumors. Cancer Research 2016 (in press).

Edmund K Moon,Raghuveer Ranganathan, Evgeniy Eruslanov, Soyeon Kim, Kheng Newick, Shaun O'Brien, Albert Lo, Xiaojun Liu, Yangbing Zhao, and Steven M. Albelda : Blockade of Programmed Death 1 Augments the Ability of Human T cells Engineered to Target NY-ESO-1 to Control Tumor Growth after Adoptive Transfer Clinical Cancer Research 22: 436-7, 2016.

Kennedy Gregory T, Judy Brendan F, Bhojnagarwala Pratik, Moon Edmund K, Fridlender Zvi G, Albelda Steven M, Singhal Sunil: Surgical cytoreduction restores the antitumor efficacy of a Listeria monocytogenes vaccine in malignant pleural mesothelioma. Immunology letters 166(1): 28-35, May 2015.

Enxiu Wang , Dr. Liang-Chuan S. Wang , Ching-Yi Tsai , Vijay Bhoj , Zachary Gershenson , Dr. Edmund K. Moon , Dr. Kheng Newick , Dr. Jing Sun , Mr. Albert Lo , Timothy Baradet , Dr. Michael Feldman , Dr. David M. Barrett , Dr. Ellen Pure , Dr. Steven M. Albelda : Generation of Potent T cell Immunotherapy for Cancer using Killer Immunoglobulin-like Receptor-based Chimeric Immunoreceptors Cancer Immunology Research 3: 815-26, 2015.

Kheng Newick, Shaun O'Brien, Veena Kapoor, Liang-chuan Wang, Edmund Moon, Daniel Sterman, Steven Albelda: Histamine dihydrochloride as an immune modulator for solid tumors. AACR 2015 (Philadelphia, PA) 2015.

Beatty Gregory L, Moon Edmund K: Chimeric antigen receptor T cells are vulnerable to immunosuppressive mechanisms present within the tumor microenvironment. Oncoimmunology 3(11): e970027, Nov 2014.

M. Heskel, E.P. Xanthopoulos, A.T. Berman, W. Levin, A. Vachani, A. Haas, D.H. Sterman, A. Lanfranco, E. Moon, M.N. Corradetti, S.M. Hahn, K.A. Cengel, R. Rengan, C.B. Simone: Safety and Efficacy of Stereotactic Body Radiation Therapy (SBRT) Reirradiation for New or Recurrent Pulmonary Malignancies Following Previous In-Field Conventionally Fractionated Thoracic Radiation Therapy International journal of radiation oncology, biology, physics 90(1): S625, September 2014.

Moon EK, Litzky LA, Sterman DH: Malignant mesothelioma and other primary pleural tumors. Fishman’s Pulmonary Diseases and Disorders. 5th ed. Grippi M, Elias J, Fishman J, et al. (eds.). McGraw-Hill, 2014.

Wang LC, Riese MJ, Moon EK, Albelda SM: Overcoming intrinsic inhibitory pathways to augment the antineoplastic activity of adoptively transferred T cells: Re-tuning your CAR before hitting a rocky road. Oncoimmunology 2(11): e26492, November 2013.

Moon EK, Wang LC1 Dolfi DV, Wilson CB, Sun J, Kapoor V, Milone MC, June CH, Riley JL, Wherry EJ, Albelda SM: Multifactorial T cell Hypofunction That is Reversible Can Limit the Efficacy of Chimeric Antibody Receptor-transduced Human T cells in Solid Tumors. Clinical Cancer Research 20(16): 4262-73, August 2013.

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Last updated: 02/10/2016
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