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Edmund K Moon, MD

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
University of Pennsylvania/Pulmonary
Stemmler Hall, 2nd Floor, Lab 261
3450 Hamilton Walk
Philadelphia, PA 19104
Office: (215) 908-1454
Lab: (215) 746-8008
Graduate Group Affiliations
B.A. (Biology & Psychology)
The Johns Hopkins University, 2000.
University of Maryland School of Medicine , 2004.
Post-Graduate Training
Internal Medicine Residency, Temple University, 2004-2007.
Pulmonary, Allergy, & Critical Care Fellowship, University of Pennsylvania, 2007-2011.
Interventional Pulmonary Fellowship, University of Pennsylvania, 2011-2012.
American Board of Internal Medicine, 2007.
American Board of Pulmonary Disease, 2009.
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> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Moon EK, Wang LS, Bekdache K, Lynn RC, Lo A, Thorne SH, Albelda SM: Intra-tumoral delivery of CXCL11 via a vaccinia virus, but not by modified T cells, enhances the efficacy of adoptive T cell therapy and vaccines. Oncoimmunology 7(3): e1395997, January 2018.

Klampatsa A, Haas AR, Moon EK, Albelda SM: Chimeric Antigen Receptor (CAR) T cell Therapy for Malignant Pleural Mesothelioma (MPM). Cancers (epub ahead of print), September 2017.

Kheng Newick, Shaun O'Brien, Edmund Moon, Steven M. Albelda: CAR T Cell Therapy for Solid Tumors. Annual Review of Medicine February 2017.

Moon EK, Kim S, O'Brien S, Sun J, St. Jean N, Arhontoulis D, Albelda SM: Genetic blockade of the protein tyrosine phosphatase SHP1 augments CAR T cell activity against PDL1 expressing solid tumors. AACR 2017 (Washington, D.C.) 2017.

Moon EK, Kim S, O'Brien S, St. Jean N, Verona R, Snyder L, Zhao Y, Albelda SM: Dual antibody blockade of TIM3 and PD1 on NYESO1 redirected human T cells leads to augmented control of lung cancer tumors. AACR 2017 (Washington, D.C.) 2017.

Kim S, Moon EK: Development of novel avenues to overcome challenges facing CAR T cells. Translational Research epub ahead of print, 2017.

Moon EK, Langer CJ, Albelda SM: The Era of Checkpoint Blockade in Lung Cancer: Taking the Brakes Off the Immune System. Annals of the American Thoracic Society epub ahead of print, 2017.

Matthew Riese, Edmund Moon, Bryon Johnson, Steven Albelda: Diacylglycerol kinases (DGKs): novel targets for improving T cell activity in cancer. Signaling October 2016.

Singhal S, Bhojnagarwala PS, O'Brien S, Moon EK, Garfall AL, Rao AS, Quatromoni JG, Stephen TL, Litzky L, Deshpande C, Feldman MD, Hancock WW, Conejo-Garcia JR, Albelda SM, Eruslanov EB.: Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer. Cancer Cell 30, July 2016.

Xiaojun Liu, Raghuveer Ranganathan, Shuguang Jiang, Chongyun Fang, Jing Sun, Soyeon Kim, Kheng Newick, Albert Lo, Carl H. June, Yangbing Zhao, Edmund K. Moon: A chimeric switch-receptor targeting PD1 augments the efficacy of second generation CAR T-cells in advanced solid tumors. Cancer Research 76(6): 1578-1590, Mar 2016.

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Last updated: 07/20/2018
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