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George Coukos, M.D., Ph.D.

George Coukos, M.D., Ph.D.

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Adjunct Professor of Obstetrics and Gynecology
Department: Obstetrics and Gynecology
Graduate Group Affiliations

Contact information
Université de Lausanne
Bureau BU27/01/124
Rue du Bugnon 27
Lausanne, CH-1011
Office: 41 (0)21 314 06 27
Lab: 41 (0)79 556 73 97
Education:
M.D.
University of Modena School of Medicine, Modena, Italy (Cum Laude), 1987.
Ph.D. (Reproductive Biology)
University of Patras School of Medicine, Patras, Greece, Department of Obstetrics and Gynecology, Thesis: Placental Neuropeptides: GnRH and CRH, 1990.
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Selected Publications

GT Motz, LP Wang, T Garrabrant, R Lastra, IS Hagemann, P Lal, F Benencia, MD Feldman, G Coukos: Expression of FasL on the Tumor Endothelium Establishes a Selective Immune Barrier in Tumors. Nature Med 20(6):607-15, Jun 2014.

E Matthaiou J Barrar, C Li, R Sandaltzopoulos, G Coukos, Y Omidi: Shikonin-loaded antibody-armed nanoparticles for targeted therapy of ovarian cancer. Intern J Nanother 15;9:1855-70, Apr 2014.

C Li, AM Chacko, J Hu, K Hasegawa, J JeSwails, L Grasso, WS El-Deiry, N Nicolaides, VR Muzykantov, CR Divgi, G Coukos: Antibody-Based Tumor Vascular Theranostics Targeting the Human Endosialin/TEM1 In Vivo. Ca Biol Ther 15(4):443-51, Apr 2014.

J Facciponte, X Ping, J Rueter, G Coukos, A Facciabene: A DNA Vaccine against the Tumor Endothelial Marker 1 Targets the Tumor Vasculature. J Clin Invest 1;124(4):1497-511, Apr 2014.

AM Chacko, C Li, M Nayak, JL Mikitsh, J Hu, J Hou, L Grasso, N Nicolaides, VR Muzykantov, CR Divgi, G Coukos: Development of Tumor Immuno-PET Imaging Targeting Vascular TEM1/Endosialin. J Nuclear Med 55(3):500-7, Mar 2014.

Q Ye, D Song, M Poussin, T Yamamoto, A Best, C Li, G Coukos, DJ Powell Jr: CD137 accurately identifies and enriches for naturally-occurring tumor-reactive T cells in tumor. Clin Cancer Res 1;20(1):44-55, Jan 2014.

J Duraiswamy, GJ Freeman, G Coukos: Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors--Response. Cancer Res 15;74(2):633-4, Jan 2014.

J Duraiswamy, GJ Freeman, G Coukos: Therapeutic PD-1 Pathway Blockade Augments with other Modalities of Immunotherapy to Prevent Immune Decline in Ovarian Cancer. Cancer Res 1;73(23):6900-12, Dec 2013.

JY Yang, K Yoshihara, K Tanaka, M Hatae, H Masuzaki, H Itamochi, M Takano, K Ushijima, JL Tanyi, G Coukos, Y Lu, GB Mills, RG Verhaak: Predicting time to ovarian carcinoma recurrence using protein markers. J Clin Invest 3;123(9):3740-50, Sep 2013.

CL Chiang, LE Kandalaft, J Tanyi, AR Hagemann, GT Motz, N Svoronos, K Montone, GM Mantia-Smaldone, L Smith, HL Nisenbaum, BL Levine, M Kalos, BJ Czerniecki, DA Torigian, DJ Powell Jr, R Mick, G Coukos: A dendritic cell vaccine pulsed with autologous hypochlorous acid-oxidized ovarian cancer lysate primes effective broad antitumor immunity: from bench to bedside. Clin Cancer Res 1;19(17):4801-15, Sep 2013.

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Last updated: 11/03/2014
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