Perelman School of Medicine/ Faculty Search/ Jeffrey S Barrett

Jeffrey S Barrett, PhD, FCP

Research Professor of Pediatrics

Department: Pediatrics

Graduate Group Affiliations

Pharmacology

Contact information

The Children's Hospital of Philadelphia
Colket Translational Research Building, Room 4012
3501 Civic Center Boulevard
Philadelphia, PA 19104-4318

Office: (267) 426-5479
Fax: (267) 425-0114

Email:
barrettj@email.chop.edu

Links
Kinetic Modeling and Simulation (KMAS) develops drug assays; performs tracer kinetic studies; novel approaches to PKPD data analysis; PKPD and tracer kinetic modeling and develops modules for educational initiatives pursued within the CTSA

Education:
BS (Chemical Engineering)
Drexel University, 1986.
MS (Pharmacokinetics)
University of Michigan, 1987.
PhD (Pharmacokinetics)
University of Michigan, 1990.

Permanent link

Perelman School of Medicine > Faculty > Search

Selected Publications

Dombrowsky E, Jayaraman B, Narayan M, Barrett JS: Evaluating Performance of a Decision Support System to Improve Methotrexate Pharmacotherapy in Children with Cancer. J. Ther. Drug Monitoring 33(1): 99-107, 2011.

Barrett JS: Modeling and Simulation in Pediatric Research and Development. Clinical Trial Simulations: Applications & Trends. Holly Kimko and Carl Peck (eds.). Springer Science + Business Media, 2011.

Mondick JT, Johnson BM, Haberer LJ, Sale ME, Adamson PC, Barrett JS, Coté CJ, Croop JM, Russo MW, Hoke JF: Population Pharmacokinetics of Intravenous Ondansetron in oncology and surgical patients aged 1 to 48 months. Eur J Clin Pharmacol 66(1): 77-86, 2010.

Shi J and Barrett, JS: Pharmacometrics in pediatric drug development and rationale dosage. Chinese J Clin Pharm Ther 15(1): 1-10, 2010.

Kimura T, Kashiwase S, Makimoto A, Kumagai M, Taga T, Ishida Y, Ida K, Nagatoshi Y, Mugishima H, Kaneko M, Barrett JS: Pharmacokinetic and pharmacodynaminc Investigation of Irinotecan hydrochloride in Pediatric Patients with Recurrent or Progressive Solid Tumors. Int J Clin Pharmacol Ther 48(5): 327-334, 2010.

Zhang AY, Skolnik JM, Barrett JS: Evaluating the Extent of Chemotherapeutic Contamination from Central Venous Catheters in Children with Cancer and Providing Guidance for Accurate Reporting of PK Parameters. PAGE 19, Berlin, Germany, Abstr 1789 [www.page-meeting.org/?abstract=1789] 2010.

Hirankarn S, Dombrowsky E, Barrett JS: Population K-PD Model of Sodium Nitroprusside in Children. J Clin Pharmacol (Abstr 91) 50(9): 1078, 2010.

Zhang AY, de Wildt S, Barrett JS: Population Pharmacokinetics of Tacrolimus in Pediatric Patients During fourteen days Following Liver Transplantation. J Clin Pharmacol (Abstr 150) 50(9): 1092, 2010.

Marsenic O, Zhang L, Zuppa A, Barrett JS, Pfister M: Application of Individualized Bayesian Urea Kinetic Modeling to pediatric hemodialysis. ASAOI J 56(3): 246-53, 2010.

Jayaraman B, Dombrowsky E, Marsteller D, Winkler J, Barrett JS: A SAS-based Solution for NONMEM run management and post-processing. PAGE 19, Berlin, Germany, Abstr 1781 [www.page-meeting.org/?abstract=1781] 2010.