Lili Wang, Ph.D.
Lili Wang, Ph.D.
Research Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Contact information
125 S. 31st Street
Suite 2000
Philadelphia, PA 19104
Suite 2000
Philadelphia, PA 19104
Office: 215-746-8929
Fax: 215-494-5443
Fax: 215-494-5443
Email:
liliwang@mail.med.upenn.edu
liliwang@mail.med.upenn.edu
Education:
B.S. (Biology)
Fudan University, Shanghai, China, 1986.
PhD (Microbiology & Molecular Genetics)
Rutgers University & Robert Wood Johnson Medical School, New Brunswick, New Jersey , 1996.
Permanent linkB.S. (Biology)
Fudan University, Shanghai, China, 1986.
PhD (Microbiology & Molecular Genetics)
Rutgers University & Robert Wood Johnson Medical School, New Brunswick, New Jersey , 1996.
Description of Research Expertise
Viral vectors, gene therapy, immune response, metabolic diseases and animal modelsSelected Publications
Li X, Cao H, Wang Q, Biao Di, Wang M, Lu J, Pan L, Yang L, Mei M, Pan X, Li G, and Wang L.: Novel AAV-based genetic vaccines encoding truncated dengue virus envelope proteins elicit humoral immune responses in mice. Microbes and Infection 14(11): 1000-7, September 2012.Wang L, Wang H, Bell P, McMenamin D, and Wilson JM. : Hepatic Gene Transfer in Neonatal Mouse by AAV8 Vector. Human Gene Therapy 23(5): 533-9, May 2012.
Beckett T, Bonneau L, Howard A, Blanchard J, Borda J, Weiner DJ, Wang L, Gao G, Kolls JK, Bohm R, Liggitt D, and Weiss DJ. : Inhalation of Nebulized Perfluorochemical Enhances Recombinant Adenovirus and AAV-Mediated Gene Expression in Lung Epithelium. Human Gene Therapy Methods 23(2): 98-110, April 2012.
Wang L*, Wang H*, Morizono H, Bell P, Jones D, Lin J, McMenamin D, Yu H, Batshaw ML, and Wilson JM. (Authors contributed equally): Sustained Correction of OTC Deficiency in Spf ash Mice Using Optimized Self-complementary AAV2/8 Vectors. Gene Therapy 19(4): 404-10, April 2012.
Wang L, Morizono H, Lin J, Bell P, Jones D, McMenamin D, Yu H, Batshaw ML, and Wilson JM. : Preclinical Evaluation of a Clinical Candidate AAV8 Vector for Ornithine Transcarbamylase (OTC) Deficiency Reveals Functional Enzyme from Each Persisting Vector Genome. Molecular Genetics and Metabolism 105(2): 203-211, February 2012.
Wang L, Calcedo R, Bell P, Lin J, Grant R, Siegel DL, and Wilson JM. : Impact of Pre-existing Immunity on Gene Transfer to Nonhuman Primate Liver with Adeno-associated Virus 8 Vectors Human Gene Therapy 22(11): 1389-1401, November 2011.
Wang L, Bell P, Lin J, Calcedo R, Tarantal AF, and Wilson JM: AAV8-mediated Hepatic Gene Transfer in Infant Rhesus Monkeys (Macacca mulatta). Molecular Therapy 19(11): 2012-2020, November 2011.
Bell P, Wang L, Gao G, Haskins ME, Zhu Y, Yu H, McCarter RJ, and Wilson JM: Inverse Zonation of Hepatocyte Transduction with AAV Vectors Between Mice and Non-human Primates. Molecular Genetics and Metabolism 104(3): 395-403, November 2011.
Wang L, Louboutin JP, Bell P, Greig J, Li Y, Wu D, and Wilson JM: Muscle-directed Gene Therapy for Hemophilia B with More Efficient and Less Immunogenic AAV Vectors. Journal of Thrombosis and Haemostasis 9(10): 2009-19, October 2011.
Calcedo R, Morizono H, Wang L, McCarter RJ, Batshaw ML, and Wilson JM: Adeno-associated Virus Antibody Profiles in Newborns, Children and Adolescents. Clinical and Vaccine Immunology 18(9): 1586-8, September 2011.