Bruce Joseph Giantonio, M.D.
Bruce Joseph Giantonio, M.D.
Associate Professor of Medicine at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia
Department: Medicine
Contact information
16 Penn Tower
3400 Spruce Street
Philadelphia, PA 19104
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-6318
Fax: 215-349-5326
Fax: 215-349-5326
Email:
bruceg@mail.med.upenn.edu
bruceg@mail.med.upenn.edu
Education:
St. Michael’s College, 1979.
BA (Biology)
Hofstra University, 1980.
MS (Physiology/Biophysics)
Georgetown University, 1983.
M.D.
Georgetown University, 1987.
Permanent linkSt. Michael’s College, 1979.
BA (Biology)
Hofstra University, 1980.
MS (Physiology/Biophysics)
Georgetown University, 1983.
M.D.
Georgetown University, 1987.
Description of Research Expertise
Clinical Investigation of targeted agents in gastrointestinal malignanciesDescription of Clinical Expertise
Treatment of all gastrointestinal malignanciesSelected Publications
Dolinsky, C.M., Mahmoud, N.N., Sun, W., Whittington, R.W., Solin, L.J., Haller, D.G., Giantonio, B.J., O’Dwyer, P.J., Rosato, E.F., Fry, R.D., Metz, J.M. : Effect of time interval between surgery and preoperative chemoradiotherapy with 5-Fluorouracil or 5-fluorouracil and oxaliplatin on outcomes in rectal cancer. J Surg Oncol 96(3): 207-212, 2007.Giantonio, B., Catalano, P.J., Meropol, N.J., O’Dwyer, P.J., Michell, E. P., Alberts, S.R., Schwartz, M.A., Benson, A.B. : Bevacizumab in Combination with Oxaliplatin, Fluorouracil and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 25(12): 1539-1544, 2007.
Giantonio, B.J.: Bevacizumab in the treatment of metastatic colorectal cancer (mCRC) in second- and third-line settings. Seminars in Oncology 33(5 Suppl 10): S15-8, 2006.
Giantonio, B., Levy, D., O’Dwyer, P., Meropol, N., Catalano, P., Benson, A. 3rd: A Phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Group Study E2200 Ann Oncol 17(9): 1399-1403, 2006.
Veronese, M.L., Sun, W., Giantonio, B., Berlin, J., Shults, J., Davis, L., Haller, D.G., O'Dwyer, P.J. : A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer. British Journal of Cancer 92(10): 1846-1849, 2005.
Bilenker, J.H., Flaherty, K.T., Rosen, M., Davis, L., Gallagher, M., Stevenson, J.P. Sun, W., Vaughn, D., Giantonio, B., Zimmer, R., Schnall, M., O'Dwyer, P.J.: Phase I trial of combretastatin a-4 phosphate with carboplatin. Clin Cancer Research 11(4): 1527-1533, 2005.
Bilenker, J.H., Stevenson, J.P., Flaherty K.T., Algazy, K., McLaughlin, K., Haller, D.G., Giantonio, B.J., Koehler, M., Garcia-Vargas, J.E., O’Dwyer, P.J.: Phase I trial of the antifolate ZD9331 in combination with cisplatin in patients with refractory solid malignancies. Cancer Chemother Pharmacol 53(4): 357-360, April 2004.
Giantonio, B.J., Derry, C., McAleer, C., McPhillips, J.J., O’Dwyer, P.J: Phase I and pharmacokinetic study of the cytotoxic ether lipid ilmofosine administered by weekly 2 hour infusion in patients with advanced solid tumors Clin Cancer Research 10: 1282-1288, 2004.
Sun, W., Whittington, R., Gallagher, M., O'Dwyer, P., Giantonio, B., Metz, J., Haller, D. : Concurrent RT with 5-FU/epirubicin and cisplatin or irinotecan for locally advanced upper GI adenocarcinoma. Oncology. 18((14 Suppl 14)): 39-42, 2004.
Veronese, M.L., Stevenson, J.P., Sun, W., Redlinger, M., Algazy, K., Giantonio, B., Hahn, S., Vaughn, D., Thorn, C., Whitehead, A.S., Haller, D.G., O’Dwyer, P.J. : Phase I trial of UFT/Leucovorin and irinotecan in patients with advanced cancer. Eur J Cancer 40: 508-514, 2004.