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Intae Lee, Ph.D.

Intae Lee, Ph.D.

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Research Assistant Professor of Radiation Oncology
Department: Radiation Oncology

Contact information
3620 Hamilton Walk
1 John Morgan Building
Philadelphia, PA 19104
Office: 215-898-9100
Fax: 215-898-0868
Lab: 215-898-8692
Education:
M.S. (Biophysical Sciences)
University of Minnesota, 1986.
Ph.D. (Biophysical Sciences)
University of Minnesota, 1988.
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Perelman School of Medicine > Faculty > Search

Selected Publications

Lee Intae, Dodia Chandra, Chatterjee Shampa, Feinstein Sheldon I, Fisher Aron B: Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2). American journal of physiology. Lung cellular and molecular physiology 306(7): L635-44, Apr 2014.

Lee Intae, Dodia Chandra, Chatterjee Shampa, Zagorski John, Mesaros Clementina, Blair Ian A, Feinstein Sheldon I, Jain Mahendra, Fisher Aron B: A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung. The Journal of pharmacology and experimental therapeutics 345(2): 284-96, May 2013.

Lee, J., Sunar, U., Tuttle, S., Shogen, K., Lee, I.: Differential effect of 1-buthionine sulfoximide ┬▒ ranpirnase on human lung cancer and lung fibroblast cells. Cancer Therapy 7: 454-463, 2009.

Lee, I., Shogen, K.: Mechanisms of enhanced tumoricidal efficacy of mulitple small dosages of ranpirnase, the novel cytotoxic ribonuclease, on lung cancer. Cancer Chemotherapy & Pharmacology 62: 337-346, 2008.

Lee, I., Kalota, A., Gewirtz, A.M., Shogen K.: Antitumor efficacy of the cytotoxic RNase, ranpirnase, on A549 human lung cancer xenografts of nude mice. Anticancer Res. 27: 299-308, 2007.

Kim, D.H., Kim, E.J., Kalota, A., Gewirtz, A.M., Glickson, J., Shogen, K., Lee, I.: Possible mechanisms of improved radiation response by cytotoxic RNase, Onconase®, on A549 human lung cancer xenografts of nude mice. Adv. in Exp. Med. Biol. 599: 53-60, 2007.

Lee, I., Kim, D.H., Sunar, U., Magnitsky, S., Shogen, K.: The therapeutic mechanisms of ranpirnase-induced enhancement of radiation response on A549 human lung cancer. IN VIVO 21: 721-728, 2007.

Wu, S.P., Lee, I., Ghoroghchian, P.P., Frail, P.R., Zheng, G., Glickson, J.D., Therien, M.: Near-infrared optical imaging of B16 melanoma cells via low-density lipoprotein-mediated uptake and delivery of high emission dipole strength tris [(porphinato) zink(II)] fluorophores. Bioconjugate Chem. 16: 542-550, 2005.

Donnelly, E.T., Liu, Y., Fatunmbi, Y.O., Lee, I., Magda, D., Rockwell, S.: Effects of Texaphyrines on the oxygenation of EMT6 mouse mammary tumors. Int. J. Radiat. Oncol. Biol. Phys. 58: 1570-1576, 2004.

Lee, I., Lee, Y.H., Mikulski, S.M., Shogen, K.: Effect of onconase ┬▒ tamoxifen on ASPC-1 human pancreatic tumors in nude mice. Adv. in Exp. Med. & Biol. 530: 187-196, 2003.

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Last updated: 05/21/2014
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