Seung Cheol Lee, Ph.D.
Seung Cheol Lee, Ph.D.
Research Assistant Professor of Radiology
Department: Radiology
Contact information
B6 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-746-7387
Fax: 215- 573-2113
Fax: 215- 573-2113
Email:
seungch@mail.med.upenn.edu
seungch@mail.med.upenn.edu
Education:
B.S. (Physics)
Korea Advanced Institute of Science and Technology, 1993.
M.S. (Solid State Physics)
Korea Advanced Institute of Science and Technology, 1995.
Ph.D. (Solid State Physics)
Korea Advanced Institute of Science and Technology, 2001.
Permanent linkB.S. (Physics)
Korea Advanced Institute of Science and Technology, 1993.
M.S. (Solid State Physics)
Korea Advanced Institute of Science and Technology, 1995.
Ph.D. (Solid State Physics)
Korea Advanced Institute of Science and Technology, 2001.
Description of Research Expertise
MRI and MRS of cancer cells, animal models and human patientsPrediction and early detection of therapeutic response in non-Hodgkin's lymphoma
Selected Publications
Xu, H.N., Zhao, H., MIR, T.A., Lee, S.C., Feng, M., Choe, R., Glickson, J.D., Li, L.Z.: CHOP therapy induced mitochondrial redox state alteration in non-Hodgkin's lymphoma xenografts. Journal of Innovative Optical Health Sciences 6(2): 1350011, April 2013.Nath, K., Nelson, D.S., Ho, A., Lee, S.C., Darpolar, M., Pickup, S., Zhou, R., Heitjan, D.F., Leeper, D.B., Glickson, J.D.: 31P and 1H MRS of DB-1 Melanoma Xenografts: Lonidamine Selectively Decreases Tumor Intracellular pH and Energy Status and Sensitizes Tumors to Melphalan. NMR in Biomedicine 26(1): 98-105, January 2013.
Lee, S.C., Marzec, M., Liu, X., Wehrli, S., Kantekure, K., Ragunath, P.N., Nelson, D.S., Delikatny, E.J., Glickson, J.D., Wasik, M.A.: Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma. NMR in Biomedicine 26(1): 106-114, January 2013.
Lee, S.C., Arias-Mendoza, F., Poptani, H., Delikatny, E.J., Wasik, M., Marzec, M., Schuster, S.J., Nasta, S.D., Svoboda, J., Goldstein, S.C., Glickson, J.D. : Prediction and early detection of response by NMR spectroscopy and imaging. PET Clinics 7: 119-126, January 2012.
Lee, S.C., Potani, H., Delikatny, E.J., Pickup, S., Nelson, D.S., Schuster, S.J., Nasta, S.D., Svoboda, J., Goldstein, S.C., Wallace, S.G., Loevner, L.A., Mellon, E.A., Reddy, R., Glickson, J.D.: NMR Metabolic and Physiological Markers of Therapeutic Response. Advances in Experimental Medicine and Biology 915: 129-135, January 2011.
Lee, S.C., Poptani, H., Pickup, S., Jenkins, W.T., Kim, S., Koch, C.J., Delikatny, E.J., Glickson, J.D.: Early detection of radiation response in non-Hodgkin’s lymphoma xenografts by 1H MR spectroscopy and imaging. NMR in Biomedicine 23(6): 624-632, July 2010.
Mellon, M.A., Lee, S.C., Pickup, S., Kim, S., Goldstein, S.C., Floyd, T.F., Poptani, H., Delikatny, E.J., Reddy, R., Glickson, J.D. : Detection of lactate with a Hadamard slice selected, selective multiple quantum coherence, chemical shift imaging sequence (HDMD-SelMQC-CSI) on a clinical MRI scanner: Application to tumors and muscle ischemia. Magnetic Resonance in Medicine 62: 1404-1413, December 2009.
Lee, S.C., Kim, K., Kim, J., Yi, J.H., Lee, S., Cheong, C.: MR microscopy of micron scale structures. Magnetic Resonance Imaging 27: 828-833, July 2009.
Lee, S.C., Delikatny, E.J., Poptani, H., Glickson, J.D.: In vivo 1H MRS of WSU-DLCL2 human non-Hodgkin’s lymphoma xenografts: response to rituximab and rituximab plus CHOP. NMR in Biomedicine 22: 259-265, April 2009.
Lee, S.C., Huang, M.Q., Nelson, D.S., Pickup, S., Wehrli, S., Adegbola, O., Poptani, H., Delikatny, E.J., Glickson, J.D. : In vivo MRS markers of response to CHOP chemotherapy in the WSU-DLCL2 human diffuse large B-cell lymphoma xenografts. NMR in Biomedicine 21: 723-733, August 2008.