Nadia Dahmane, Ph.D.
Nadia Dahmane, Ph.D.
Research Assistant Professor of Neurosurgery
Department: Neurosurgery
Contact information
Permanent linkUniversity of Pennsylvania
Department of Neurosurgery
502C Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104
Department of Neurosurgery
502C Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104
Office: 215-573-0837
Email:
dahmanen@mail.med.upenn.edu
dahmanen@mail.med.upenn.edu
Selected Publications
Demarest, R. M., Dahmane, N., Capobianco, A. J.: Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia. Blood 117(10): 2901-9, 2011.Zhang, Z., Baubet, V., Ventocilla, C., Xiang, C., Dahmane, N.*, Winkler, J. D.*: Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of Hedgehog signaling based on cyclopamine. Organic Letters 13(18): 4786-9, 2011 Notes: (*: corresponding authors).
Zabierowski, S. E., Baubet, V., Himes, B., Li, L., Fukunaga-Kalabis, M., Patel, S., McDaid, R., Guerra, M., Gimotty, P., Dahmane, N., Herlyn, M.: Direct reprogramming of melanocytes to neural crest stem-like cells by one defined factor. Stem Cells 29(11): 1752-62, 2011.
Xiang, C., Baubet, V., Pal, S., Holderbaum, L., Tatard, V., Jiang, P., Davuluri, R. V., Dahmane, N.: RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death and Differentiation 2011.
Winkler, J. D.*, Isaacs, A. K., Xiang, C., Baubet, V., Dahmane, N.*: Design, synthesis, and biological evaluation of estrone-derived hedgehog signaling inhibitors. Tetrahedron 67(52): 10261-10266, 2011 Notes: (*: corresponding authors).
Pal, S., Gupta, R., Kim, H., Wickramasinghe, P., Baubet, V., Showe, L. C., Dahmane, N., Davuluri, R. V.: Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar development. Genome Research 21(8): 1260-72, 2011.
Isaacs, A. K., Xiang, C., Baubet, V., Dahmane, N.*, Winkler, J. D.*: Studies directed toward the elucidation of the pharmacophore of steroid-based Sonic Hedgehog signaling inhibitors. Organic Letters 13(19): 5140-3, 2011 Notes: (*: corresponding authors).
Fernandez, C., Tatard, V. M., Bertrand, N., Dahmane, N.: Differential modulation of Sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network. Developmental Neuroscience 32(1): 59-70, 2010.
Tokhunts, R., Singh, S., Chu, T., D'Angelo, G., Baubet, V., Goetz, J. A., Huang, Z., Yuan, Z., Ascano, M., Zavros, Y., Therond, P. P., Kunes, S., Dahmane, N., Robbins, D. J.: The full-length unprocessed hedgehog protein is an active signaling molecule. Journal of Biological Chemistry 285(4): 2562-8, 2010.
Tatard, V. M., Xiang, C., Biegel, J. A., Dahmane, N.: ZNF238 is expressed in postmitotic brain cells and inhibits brain tumor growth. Cancer Research 70(3): 1236-46, 2010.