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Paris Margaritis, D.Phil

Paris Margaritis, D.Phil

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Research Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
Rm 5024 Colket Translational Research Building
The Children's Hospital of Philadelphia
3501 Civic Center Blvd.
Philadelphia, PA 19104
Office: 2674267262
Fax: 2155903660
Lab: 2674267262
Education:
BSc (Hons) (Genetics)
The University of Newcastle-upon-Tyne (UK), 1995.
DPhil (Molecular Biology and Gene Therapy)
The University of Oxford (UK), 2000.
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Selected Publications

Balestra Dario, Faella Armida, Margaritis Paris, Cavallari Nicola, Pagani Franscesco, Bernardi Franscesco, Arruda Valder R., Pinotti Mirko: An engineered U1 small nuclear RNA rescues splicing-defective coagulation F7 gene expression in mice. Journal of Thrombosis and Haemostasis 12, Feb 2014.

Margaritis Paris: Does rFVIIa work solo in hemophilia? Blood 123: 1631-1633, 2014.

Yazicioglu Mustafa N., Monaldini Luca, Chu Kirk, Khazi Fayaz R., Murphy Samuel L., Huang Heshu, Margaritis Paris, High Katherine A.: Cellular Localization and Characterization of Cytosolic Binding Partners for Gla-containing Proteins PRRG4 and PRRG2. Journal of Biological Chemistry Sep 2013.

Crudele Julie M, Van Sluis Geerte L., Margaritis Paris, Siner Joshua I, Mauer jenna, Faella Armida, Zhou Shangzhen, Esmon Charles T., High Katherine A. Spek Arnold C., Arruda Valder R.: Mechanistic insights into zymogen protein C protection against cancer progression. International Society of Thrombosis and Haemostasis meeting, Amsterdam, The Netherlands. Jul 2013.

Pavani Giulia, Ivanciu Lacramioara, Faella Armida, Margaritis Paris: EPCR binding to Factor VIIa enhances its hemostatic function in vivo. International Society of Thrombosis and Haemostasis meeting, Amsterdam, The Netherlands. Jul 2013.

Balestra Dario, Faella Armida, Cavallari Nicola, Margaritis Paris, Pagani Franco, Bernardi Francesco, Arruda Valer R., Pinotti Mirko: Delivery of a modified u1 small nuclear rna alleviates splicing-defective coagulation factor VII expression in mouse models. International Society of Thrombosis and Haemostasis meeting, Amsterdam, The Netherlands. Jul 2013.

Crudele Julie M, Van Sluis Geerte L., Margaritis Paris, Siner Joshua I, Sliozenberg Michael, Faella Armida, Zhou Shangzhen, High Katherine A. Spek Arnold C., Arruda Valder R.: Supraphysiological aPC levels reduce cancer metastasis independent of aPC’s cytoprotective effect. International Society of Thrombosis and Haemostasis meeting, Amsterdam, The Netherlands. Jul 2013.

Margaritis Paris, Bellinger Dwight A., Zhou Shangzhen, Faella Armida, Nichols Timothy C., High Katherine A.: Correction of canine Factor VII (FVII) deficiency by AAV-mediated expression of canine FVII zymogen. American Society of Gene and Cell Therapy Annual Meeting, Salt Lake City (UT) May 2013.

Arruda R Valder and Margaritis Paris: F1000.com Article Evaluation: Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. F1000.com Jan 2013.

Pavani Giulia, Ivanciu Lacramioara, Margaritis Paris: FVIIa Binding to the Endothelial Protein C Receptor Reduces Protein Recovery in Vivo. American Society for Hematology Annual Meeting, Atlanta (GA), USA Dec 2012.

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Last updated: 04/16/2014
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