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Mark E. Mikkelsen, MD, MSCE

Mark E. Mikkelsen, MD, MSCE

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Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Gates 05042
3400 Spruce Street
Hospital of the University of Pennsylvania
Philadelphia, PA 19104
Office: (215) 615-5416
Fax: (215) 614-0869
Lab: (267) 285-6602
BA (Political Science)
Colgate University, Hamilton, NY, 1996.
(Post-Baccalaureate Pre-Medical Degree Program)
Bryn Mawr College, Bryn Mawr, PA, 1997.
MD (Medical Degree)
University of Virginia School of Medicine, Charlottesville, VA, 2002.
MSCE (Clinical Epidemiology and Biostatistics)
University of Pennsylvania, Philadelphia, PA, 2008.
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Description of Research Expertise

Dr. Mikkelsen's research aims to improve the outcomes of critically ill patients through patient-oriented research focused on sepsis, acute lung injury, and long-term outcomes in survivors of critical illness. He is passionate in his goal to improve the delivery of care to critically ill patients and to improve the lives of survivors of critical illness.

Acute Lung Injury
Long-Term Outcomes of Critical Illness
Neuropsychological Impairment in Survivors of Critical Illness

Description of Clinical Expertise

Dr. Mikkelsen's philosophy for patient care is to ensure that exceptional, compassionate care is delivered to critically ill patients and their family members through outstanding, multi-disciplinary teamwork across the continuum of care, through the application of evidence-based care, and through systematic study to optimize our performance.

Acute Lung Injury
Rescue Therapies for Acute Lung Injury
Long-Term Neuropsychological Outcomes in Survivors of Critical Illness
Long-Term Neuropsychological Outcomes in Family Members of Critically Ill Patients

Selected Publications

Maley JH, Siruckova R, McGraw KA, Brewster I, Mayoral I, Adams S, Piech AA, Mikkelsen ME: Post-intensive care syndrome, resilience, and health-related quality of life in survivors of critical illness. Crit Care Med 2016 Notes: Accepted abstract.

Oppenheim I, Atkins J, Mikkelsen ME, Gittleman E, Choi, Leri D, Fuchs BD: Implementation of an extubation risk screening and planning protocol to improve airway safety. Crit Care Med 2016 Notes: Accepted abstract.

Maley JH, Mikkelsen ME: Sepsis survivorship: how can we promote a culture of resilience? Crit Care Med 43(2): 479-481, 2015 Notes: Editorial.

Fogarty CB, Mikkelsen ME, Gaieski DF, Small DS: Discrete optimization for interpretable study populations and randomization inference in an observational study of severe sepsis mortality. J Am Stat Assoc 2015 Notes: In press.

Drumheller BC, AGarwal A, Mikkelsen ME, Cham Sante S, Weber AL, Goyal M, Gaieski DF: Risk factors for mortality despite early protocolized resuscitation for severe sepsis and septic shock in the emergency department J Critical Care 2015 Notes: In press.

Mikkelsen ME, Iwashyna TJ: Persistent problems and recovery after critical illness. Oxford Textbook of Medicine 6e. Simon Finfer (eds.). 2015 Notes: Accepted chapter.

Mikkelsen ME, Lanken PN, Christie JD : Acute lung injury and the acute respiratory distress syndrome. Principles of Critical Care. 4th Edition. Jesse Hall, Gregory Schmidt, Lawrence Wood (eds.). (eds.). McGraw Hill, 2015 Notes: Chapter. In press.

Mikkelsen ME, Fuchs BD, Grippi MA: Organization of intensive care units and long term acute care hospitals (LTACHs). Fishman's Pulmonary Diseases and Disorders, 5th ed. Grippi M, Elias J, Fishman J, Kotloff R, Pack A, Senior R, eds. (eds.). New York: McGraw-Hill, 2015 Notes: Chapter. In press.

Ortego A, Gaieski DF, Fuchs BD, Jones T, Halpern SD, Small DS, Sante SC, Drumheller B, Christie JD, Mikkelsen ME: Hospital-based acute care use in survivors of septic shock. Crit Care Med 43(4): 729-737, 2015.

Whittaker SA, Fuchs BD, Gaieski DF, Christie JD, Goyal M, Meyer NJ, Kean C, Small DS, Bellamy SL, Mikkelsen ME: Epidemiology and outcomes in patients with severe sepsis admitted to the hospital wards. J Crit Care 30(1): 78-84, 2015.

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Last updated: 11/05/2015
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