Tejvir S. Khurana, MD, PhD.
Tejvir S. Khurana, MD, PhD.
Professor of Physiology
Department: Physiology
Graduate Group Affiliations
Contact information
Department of Physiology,
University of Pennsylvania,
A600 Richards Building,
3700 Hamilton Walk,
Philadelphia, PA 19004
University of Pennsylvania,
A600 Richards Building,
3700 Hamilton Walk,
Philadelphia, PA 19004
Office: (215) 898-4116
Fax: (215) 573 5851
Fax: (215) 573 5851
Email:
tsk@mail.med.upenn.edu
tsk@mail.med.upenn.edu
Education:
MBBS (Medicine)
Delhi University, 1985.
Ph.D. (Neurobiology)
Harvard University, 1992.
Permanent linkMBBS (Medicine)
Delhi University, 1985.
Ph.D. (Neurobiology)
Harvard University, 1992.
Description of Research Expertise
muscle, muscular disease, muscular dystrophy, therapeutics, gene therapy, extraocular muscle, transcriptome, proteome, genomics, sports medicine, athletic doping, hypoxia, altitude, respiratory, neuromuscular junctions, synapses.Description of Clinical Expertise
High altitude medicineSelected Publications
Pistilli EE, Bogdanovich S, Goncalves MD, Ahima RS, Lachey J, Seehra J, Khurana T*: Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy. Am. J.Path. 178: 1287-1297, 2011.Zeiger U & Khurana TS*: Distinctive Patterns of MicroRNA Expression in Extraocular Muscles. Physiol. Genomics 41: 289-296, 2010
Pistilli EE, Bogdanovich S, Mosqueira M, Lachey J, Seehra JS & KhuranaTS*: Pre-treatment with a soluble activin type IIB receptor/Fc fusion protein improves hypoxia-induced muscle dysfunction. Am. J. Physiol. 298: R96-R103, 2010.
Baby SM, Bogdanovich S, Willmann G, Basu U, Lozynska O, & Khurana TS* : Differential Expression of Utrophin-A and -B Promoters in the Central Nervous System (CNS) of Normal and dystrophic mdx Mice. Brain Path. 20: 323-342, 2010.
Zeiger U, Mitchell CH, Khurana TS*: Superior calcium homeostasis of extraocular muscles. Exp. Eye. Res 91: 613-622, 2010.
Hickey MM, Richardson T, Wang T, Mosqueira M, Arguiri E, Yu H, Yu QC, Solomides CC, Morrisey EE, Khurana TS, Christofidou-Solomidou M, Simon MC.: The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice. J Clin. Invest. 120: 827-839, 2010.
Ketterer C, Zeiger U, Budak MT, Rubinstein NA & Khurana TS*: Identification of the neuromuscular junction (NMJ) transcriptome of extraocular muscle (EOM) by laser capture microdissection (LCM). Invest. Opthal. Vis. Sci. 51: 4589-4599, 2010.
Goncalves MD, Pistilli EE, Balduzzi A, Birnbaum MJ, Lachey J, Khurana TS, Ahima RS: Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition. PLoS One 15: e12707, 2010.
Willmann G, Ivanov IV, Fischer MD, Lahiri S, Pokharel RK, Werner A, Khurana TS: Effects on colour discrimination during long term exposure to high altitudes on Mt Everest. Brit. J. Opthal 94: 1393-1397, 2010.
Mosqueira M, Willmann G, Ruohola-Baker H & Khurana TS*: Chronic hypoxia impairs muscle function in the Drosophila model of Duchenne's muscular dystrophy (DMD). PLoS One 5: e13450, 2010.