Tejvir S. Khurana, MD, PhD.
Tejvir S. Khurana, MD, PhD.
Professor of Physiology
Department: Physiology
Graduate Group Affiliations
Contact information
Department of Physiology,
University of Pennsylvania,
A600 Richards Building,
3700 Hamilton Walk,
Philadelphia, PA 19004
University of Pennsylvania,
A600 Richards Building,
3700 Hamilton Walk,
Philadelphia, PA 19004
Office: (215) 898-4116
Fax: (215) 573 5851
Fax: (215) 573 5851
Email:
tsk@mail.med.upenn.edu
tsk@mail.med.upenn.edu
Education:
MBBS (Medicine)
Delhi University, 1985.
Ph.D. (Neurobiology)
Harvard University, 1992.
Permanent linkMBBS (Medicine)
Delhi University, 1985.
Ph.D. (Neurobiology)
Harvard University, 1992.
Description of Research Expertise
muscle, muscular disease, muscular dystrophy, therapeutics, gene therapy, extraocular muscle, transcriptome, proteome, genomics, sports medicine, athletic doping, hypoxia, altitude, respiratory, neuromuscular junctions, synapses.Description of Clinical Expertise
High altitude medicineSelected Publications
Mosqueira M, Willmann G, Zeiger U, Khurana TS: Expression profiling reveals novel hypoxic biomarkers in peripheral blood of adult mice exposed to chronic hypoxia. PLoS One 7(5): e37497, 2012.Moorwood C, Soni N, Patel G, Wilton SD, Khurana TS: A Cell-Based High-Throughput Screening Assay for Posttranscriptional Utrophin Upregulation. J Biomol Screen 2012.
Pistilli EE, Bogdanovich S, Goncalves MD, Ahima RS, Lachey J, Seehra J, Khurana T*: Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy. Am. J.Path. 178: 1287-1297, 2011.
Moorwood C, Lozynska O, Suri N, Napper AD, Diamond SL, Khurana TS: Drug discovery for Duchenne muscular dystrophy via utrophin promoter activation screening. PLoS One 6(10): e26169, 2011.
Basu U, Lozynska O, Moorwood C, Patel G, Wilton SD, Khurana TS: Translational regulation of utrophin by miRNAs. PLoS One 6(12): e29376, 2011.
Amenta AR, Yilmaz A, Bogdanovich S, McKechnie BA, Abedi M, Khurana TS, Fallon JR: Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice. PNAS 108: 762-767, 2011.
Zeiger U & Khurana TS*: Distinctive Patterns of MicroRNA Expression in Extraocular Muscles. Physiol. Genomics 41: 289-296, 2010
Pistilli EE, Bogdanovich S, Mosqueira M, Lachey J, Seehra JS & KhuranaTS*: Pre-treatment with a soluble activin type IIB receptor/Fc fusion protein improves hypoxia-induced muscle dysfunction. Am. J. Physiol. 298: R96-R103, 2010.
Willmann G, Ivanov IV, Fischer MD, Lahiri S, Pokharel RK, Werner A, Khurana TS: Effects on colour discrimination during long term exposure to high altitudes on Mt Everest. Brit. J. Opthal 94: 1393-1397, 2010.
Mosqueira M, Willmann G, Ruohola-Baker H & Khurana TS*: Chronic hypoxia impairs muscle function in the Drosophila model of Duchenne's muscular dystrophy (DMD). PLoS One 5: e13450, 2010.