Stephen M Keefe, MD, MSCE
Stephen M Keefe, MD, MSCE
Ann B. Young Assistant Professor in Cancer Research
Department: Medicine
Contact information
16 Penn Tower
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-4469
Fax: 215-349-5326
Fax: 215-349-5326
Email:
stephen.keefe@uphs.upenn.edu
stephen.keefe@uphs.upenn.edu
Education:
B.A. (Philosophy)
University of Notre Dame, 1993.
B.S.E.E. (Electrical Engineering)
University of Notre Dame, 1993.
Certif. (Post-Baccalaureate Progam in Pre-Medical Studies)
Columbia University, 1997.
M.D. (Internal Medicine)
Pritzker School of Medicine, University of Chicago, 2003.
M.S.C.E. (Clinical Epidemiology & Biostatistics, anticipated)
Perelman School of Medicine, University of Pennsylvania, 2013.
Permanent linkB.A. (Philosophy)
University of Notre Dame, 1993.
B.S.E.E. (Electrical Engineering)
University of Notre Dame, 1993.
Certif. (Post-Baccalaureate Progam in Pre-Medical Studies)
Columbia University, 1997.
M.D. (Internal Medicine)
Pritzker School of Medicine, University of Chicago, 2003.
M.S.C.E. (Clinical Epidemiology & Biostatistics, anticipated)
Perelman School of Medicine, University of Pennsylvania, 2013.
Selected Publications
Keefe SM, Cohen R, Eliasof S, Garmey EG, Mykulowicz KM, Pryma D, Haas NB: A Phase Ib-IIa Study Evaluating the Nanopharmaceutical CRLX101 in Combination with Bevacizumab in the Treatment of Patients with Advanced Renal Cell Carcinoma (NCT01625936). 2013 Assocation of American Cancer Research April 2013.Shah A, Motiwala S, O'Dwyer PJ, Flaherty KT, Keefe SM: Increase in blood pressure with sorafenib exposure in renal cell carcinoma versus other solid tumors. 2013 Genitourinary Cancers Symposium February 2013.
Keefe, S.M., Nathanson, K.L., Rathmell, W.K.: Molecular Biology of Kidney Cancer. Seminars in Oncology. Rini, B.I. (eds.). In Press 2013.
Kang, H. C. Tan, K. S. Keefe, S. M. Heitjan, D. F. Siegelman, E. S. Flaherty, K. T. O'Dwyer, P. J. Rosen, M. A.: MRI assessment of early tumor response in metastatic renal cell carcinoma patients treated with sorafenib. AJR Am J Roentgenol 200(1): 120-126, December 2012.
Shah A, Motiwala S, Brose MS, Haas NB, Vaughn D, Flaherty KT, O’Dwyer PJ, Keefe SM: Differing Rates of Blood Pressure Increase on Treatment with Sorafenib: Renal Cell Carcinoma vs. Other Solid Tumors. DOM Research Day June 2012.
Baumann BC, Guzzo TJ, He J, Vaughn DJ, Keefe SM, Vapiwala N, Deville C, Bekelman JE, Tucker K, Hwang WT, Malkowicz SB, Christodouleas JP: Bladder Cancer Patterns of Pelvic Failure: Implications for Adjuvant Radiation Therapy. Int J Radiat Oncol Biol Phys May 2012.
Baumann BC, Guzzo TJ, He J, Keefe SM, Tucker K, Bekelman JE, Hwang WT, Vaughn DJ, Bruce Malkowicz S, Christodouleas JP: A Novel Risk Stratification to Predict Local-Regional Failures in Urothelial Carcinoma of the Bladder After Radical Cystectomy. Int J Radiat Oncol Biol Phys April 2012.
Stephen M. Keefe, Andrea B. Troxel, Sarah Rhee, Kanchan Puttaswamy, Peter J. O'Dwyer, Laurie A. Loevner, Susan J. Mandel, Marcia S. Brose: Phase II trial of sorafenib in patients with advanced thyroid cancer. ASCO 2011 Annual Meeting 2011.
Stephen M. Keefe, Erick Moyneur, Sabrina Meyers, Victoria Barghout, Keith Flaherty: Dose Reductions and Delays (Interruptions) in Patients With Renal Cell Carcinoma Treated with Sorafenib or Sunitinib: Retrospective Analysis of 2 Large US Health Care Claims Databases. ASCO Annual Meeting 2010, Journal of Clinical Oncology Supplemental, June 2010.
Stephen M. Keefe, Brian L. Strom: On the importance of heterogeneity in meta-analysis. Clinical Trials 6(5): 443-444, October 2009.