James L. Kreindler, M.D.
James L. Kreindler, M.D.
Assistant Professor of Pediatrics
Department: Pediatrics
Contact information
The Children's Hospital of Philadelphia
34th Street and Civic Center Boulevard
Philadelphia, PA 19104
34th Street and Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-426-9232
Fax: 215-590-3500
Fax: 215-590-3500
Email:
kreindler@email.chop.edu
kreindler@email.chop.edu
Education:
BA (Biology)
Johns Hopkins University, 1994.
MD
Mount Sinai School of Medicine, 1998.
Permanent linkBA (Biology)
Johns Hopkins University, 1994.
MD
Mount Sinai School of Medicine, 1998.
Description of Research Expertise
Epithelial ion transportCystic Fibrosis
Description of Clinical Expertise
Cystic FibrosisLung transplantation
Selected Publications
Zhao Ke-Qing, Cowan Andrew T, Lee Robert J, Goldstein Natalia, Droguett Karla, Chen Bei, Zheng Chunquan, Villalon Manuel, Palmer James N, Kreindler James L, Cohen Noam A: Molecular modulation of airway epithelial ciliary response to sneezing. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 26(8): 3178-87, Aug 2012.Zhao Ke-Qing, Xiong Guoxiang, Wilber Morgan, Cohen Noam A, Kreindler James L: A role for two-pore K+ channels in modulating Na+ absorption and Cl- secretion in normal human bronchial epithelial cells. American journal of physiology. Lung cellular and molecular physiology 302(1): L4-L12, Sep 2011.
Cheng Guanjun, Wang Liang-Chuan S, Fridlender Zvi G, Cheng Guang-Shing, Chen Bei, Mangalmurti Nilam S, Saloura Vassiliki, Yu Zaifang, Kapoor Veena, Mozdzanowska Krystyna, Moon Edmund, Sun Jing, Kreindler James L, Cohen Noam A, Caton Andrew J, Erikson Jan, Albelda Steven M: Pharmacologic activation of the innate immune system to prevent respiratory viral infections. American journal of respiratory cell and molecular biology 45(3): 480-8, Sep 2011.
Zhao Ke-Qing, Goldstein Natalia, Yang Haibin, Cowan Andrew T, Chen Bei, Zheng Chunquan, Palmer James N, Kreindler James L, Cohen Noam A: Inherent differences in nasal and tracheal ciliary function in response to Pseudomonas aeruginosa challenge. American journal of rhinology & allergy 25(4): 209-13, Jul-Aug 2011.
Suaud Laurence, Miller Katelyn, Alvey Lora, Yan Wusheng, Robay Amal, Kebler Catherine, Kreindler James L, Guttentag Susan, Hubbard Michael J, Rubenstein Ronald C: ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells. The Journal of biological chemistry 286(24): 21239-53, Jun 2011.
Accurso Frank J, Moss Richard B, Wilmott Robert W, Anbar Ran D, Schaberg Amy E, Durham Todd A, Ramsey Bonnie W, : Denufosol tetrasodium in patients with cystic fibrosis and normal to mildly impaired lung function. American journal of respiratory and critical care medicine 183(5): 627-34, Mar 2011.
Chen Kong, Pociask Derek A, McAleer Jeremy P, Chan Yvonne R, Alcorn John F, Kreindler James L, Keyser Matthew R, Shapiro Steven D, Houghton A McGarry, Kolls Jay K, Zheng Mingquan: IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke. PloS one 6(5): e20333, 2011.
Goldstein-Daruech Natalia, Cope Emily K, Zhao Ke-Qing, Vukovic Katarina, Kofonow Jennifer M, Doghramji Laurel, González Bernardo, Chiu Alexander G, Kennedy David W, Palmer James N, Leid Jeffery G, Kreindler James L, Cohen Noam A: Tobacco smoke mediated induction of sinonasal microbial biofilms. PloS one 6(1): e15700, 2011.
Kong Jianping, Crissey Mary Ann, Funakoshi Shinsuke, Kreindler James L, Lynch John P: Ectopic Cdx2 expression in murine esophagus models an intermediate stage in the emergence of Barrett's esophagus. PloS one 6(4): e18280, 2011.
Goldfarb Samuel B, Gaynor J William, Fuller Stephanie, Kreindler James, Montenegro Lisa M, Fynn-Thompson Francis, Visner Gary: Induction therapy with antithymocyte globulin before reperfusion. The Annals of thoracic surgery 90(4): 1110-4; discussion 1114-5, Oct 2010.