Matthew J. Lazzara, PhD
Matthew J. Lazzara, PhD
Assistant Professor of Chemical & Biomolecular Engineering
Department: Chemical & Biomolecular Engineering
Graduate Group Affiliations
Contact information
Department of Chemical Engineering and Biomolecular Engineering
311A Towne Bldg.
220 S. 33rd Steet
Philadelphia, PA 19104
311A Towne Bldg.
220 S. 33rd Steet
Philadelphia, PA 19104
Office: 215-746-2264
Fax: 215-573-2093
Fax: 215-573-2093
Email:
mlazzara@seas.upenn.edu
mlazzara@seas.upenn.edu
Education:
B.S. (Chemical Engineering)
University of Florida, 1997.
PhD (Chemical Enigineering)
Massachusetts Institute of Technology, 2003.
Permanent linkB.S. (Chemical Engineering)
University of Florida, 1997.
PhD (Chemical Enigineering)
Massachusetts Institute of Technology, 2003.
Selected Publications
Lazzara MJ, Lauffenburger DA: Differential EGFR signaling in lung cancers with kinase-inhibitor-sensitizing mutations, IChe National Meeting, Salt Lake City, UT. Nov 2007.Lazzara MJ, Lauffenburger DA: Predicting enhanced response to EGFR kinase inhibitors in cancer, Biomedical Engineering Society National Meeting, Los Angeles, CA. Sept 2007.
Lazzara MJ, Deen WM: Model of albumin reabsortption in the proximal tubule. Am J Physiol Renal Physiol 292: F430-F439, 2007.
Hendriks BH, Griffiths GJ, Benson R, Kenyon D, Lazzara MJ, Swinton J, Beck S, Hickinson M, Beusmans JM, Lauffenburger DA, DeGraaf D: Decreased internalization of ErbB1 mutants in lung cancer is linked with a mechanism conferring sensitivity to gefitinib. Syst Biol 153: 457-466, 2006.
Bolton GR, Boesch AW, Lazzara MJ: The effects of flow rate on membrane capacity: Development and application of adsorptive membrane fouling models. J Memb Sci 279: 625-634, 2006.
Lazzara MJ, Jasper PJ, Sorger PK, Lauffenburger DA: Altered EGFR trafficking and signaling in Iressa-sensitive human cell lines, AIChe National Meeting, Cincinnati, OH. Nov 2005.
Jasper PJ, Lazzara MJ, Sorger PK, Luaffenburger DA: Altered EGFR trafficking and signaling in Iressa-sensitive human cell lines, International Conference on Systems Biology (ICSB), Boston, MA. Oct 2005.
James A, Lazzara MJ, Lauffenburger DA, Beusmans J: Modulation of heregulin-induced signaling by an ErbB1 kinase inhibitor, International Conference on Systems Biology, Boston, MA. Oct 2005.
Lazzara MJ, Jasper PJ, Sorger PK, Lauffenburger DA: Altered EGFR trafficking and signaling in Iressa-sensitive human cell lines, Biomedical Engineering Society (BMES) National Meeting, Baltimore, MD. Oct 2005.
Bolton GR, LaCasse D, Lazzara MJ, Kuriyel R: The fiber-coating model of biopharmaceutical depth filtration. AIChe J 51: 2978-2987, 2005.