Amanda B. Christini, MD

Description of Clinical Expertise

CLINICAL RESEARCH
2011 – present, Co-Principle Investigator: Phase 2 randomized, double-blind, placebo-controlled study of GS-5885, GS-9451, Tegobuvir and Ribavirin in interferon ineligible or intolerant subjects with chronic genotype 1a or 1b HCV infection

2011 – present, Co-Principle Investigator: Phase 2 randomized, double-blind, placebo-controlled study of GS-5885, GS-9451, Tegobuvir and Ribavirin in treatment-experienced subjects with chronic genotype 1a or 1b HCV infection

2007 Principal Investigator: Influenza vaccination and motivators among healthcare worker groups.

Description of Other Expertise

PROFESSIONAL EXPERIENCE
Maxygen, Inc. Redwood City CA 1999-2004
Consultant 2003-2004
Director, Business Development 2000-2003
Head, Business Development, Vaccines Business Unit 1999-2000
• Responsible and accountable for the following roles, reporting to President and CEO:
o Management of scientific and clinical teams responsible for product development,
o Corporate partnerships, license agreements, acquisitions and merger evaluations,
o Budget development and management, and
o Strategic planning, product portfolio management and resource allocation.
• Developed and implemented R&D plans for lead products with SVP, Clinical Development
• Led negotiations and closed deals with Aventis Pasteur, International AIDS Vaccine Initiative; contract manufacturers; university, government and corporate technology licenses and research agreements
• Managed collaborations with Aventis Pasteur, ALK-Abello, IAVI and $20M grant program with DARPA

Valentis, Inc. Burlingame, CA 1997-1999
Director, Business Development 1998-1999
Manager, Business Development 1998
Associate, Business Development 1997
• Responsible for business development for cardiovascular and oncology business units
• Led and closed multiple corporate partnerships, asset acquisitions and technology licenses
• Led integration of Business Development for Megabios in merger with GeneMedicine to form Valentis
• Developed and implemented technology acquisition strategy throughout the company

Massachusetts Institute of Technology
Office of Technology Licensing, Cambridge, MA 1995-1996
Licensing Associate
• Licensed biotechnology inventions to corporate partners and managed university patent portfolios