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James K Mangan, MD, Ph.D.

James K Mangan, MD, Ph.D.

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Assistant Professor of Clinical Medicine
Department: Medicine

Contact information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-102
34th Street and Civic Center Blvd
Philadelphia, PA 19104
Office: 215-615-3138
Fax: 215-615-5887
BS (Biology-Molecular, Cellular and Development)
Haverford College, 1998.
Temple University, 2005.
Ph.D. (Molecular Biology and Genetics)
Temple University, 2005.
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Perelman School of Medicine > Faculty > Search

Selected Publications

Mesa RA, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma X, Wilson W, Paranagama DC, Dubinski DG, Naim A, Parasuraman S, Boyle J, Mascarenhas JO. : Differences in treatment goals and perception of symptom burden between patients with myeloproliferative neoplasms (MPNs) and hematologists/oncologists in the United States: Findings from the MPN Landmark Survey. Cancer Page: epub ahead of print, September 2016.

Yam C, Crisalli L, Luger SM, Loren AW, Hexner EO, Frey NV, Mangan JK, Gao A, Stadtmauer EA, Porter DL, Reshef R. : Unrelated donors are associated with improved relapse-free survival compared to related donors in patients with myelodysplastic syndrome undergoing reduced intensity allogeneic stem cell transplantation. American Journal of Hematology 91(9): 883-887, September 2016.

Mangan JK, Chmieliauskaite M, Stoopler ET. : An intraoral mass associated with myelodysplastic syndrome. JAMA Oncology 2(5): 679-680, May 2016.

Hexner EO, Luger SM, Reshef R, Jeschke GR, Mangan JK, Frey NV, Frank DM, Richman LP, Vonderheide RH, Aqui NA, Rosenbach M, Zhang Y, Chew A, Loren AW, Stadtmauer EA, Levine BL, June CH, Emerson SG, Porter DL.: Infusion of CD3/CD28 costimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment. American Journal of Hematology 91(5): 453-460, May 2016.

Mesa R, Miller CB, Thyne M, Mangan J, Goldberger S, Fazal S, Ma X, Wilson W, Paranagama DC, Dubinski DG, Boyle J, Mascarenhas JO: Myeloproliferative neoplasms (MPNs) have a significant impact on patients' overall health and productivity: the MPN Landmark Survey. BMC Cancer 16(167), February 2016.

Ganetsky A, Crisalli LM, Huffman AP, Acosta EP, Mangan JK, Luger SM, Loren AW, Hexner EO, Frey NV, Stadtmauer EA, Hoxie JA, Vonderheide RH, Porter DL, Reshef R. : Maraviroc concentrations are highly predictive of acute graft-versus-host-disease in reduced-intensity allogeneic stem cell transplantation. European Hematology Association Annual Meeting(331), 2016.

Canaani J, Frey NV, Gill S, Luskin MR, Hexner EO, Loren AW, Luger SM, Mangan J, Porter DL, Perl AE. : Use of FLT3 inhibitors to bridge relapsed/refractory AML patients to an allogeneic stem cell transplant. American Society of Bone Marrow Transplanation/Center for International Bone Marrow Transplant Research Tandem Meetings(273), 2016.

Reshef R, Huffman AP, Gao A, Luskin MR, Frey NV, Gill SI, Hexner EO, Kambayashi T, Loren AW, Luger SM, Mangan JK, Nasta SD, Richman LP, Sell M, Stadtmauer EA, Vonderheide RH, Mick R, Porter DL: High graft CD8 cell dose predicts improved survival and enables better donor selection in allogeneic stem-cell transplantation with reduced-intensity conditioning. J Clin Oncol 33(21): 2392-2398, July 2015.

Bagley SJ, Sehgal AR, Gill S, Frey NV, Hexner EO, Loren AW, Mangan JK, Porter DL, Stadtmauer EA, Reshef R, Luger SM.: Acute cholecystitis is a common complication after allogeneic stem cell transplantation and is associated with the use of total parenteral nutrition. Biol Blood Marrow Transplant 21(4): 768-771, April 2015.

Orlowski, RJ, Mangan JK, Luger SM. : Approach to patients with primary refractory acute myeloid leukemia. Curr Opin Hematol 22(2): 97-107, March 2015.

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Last updated: 10/26/2016
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