Ulf H Beier, MD

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations

Contact information
Abramson Research Center, Room 916-C
3615 Civic Center Boulevard
Philadelphia, PA 19104
Office: (215) 590 2449
Fax: (215) 590 7385
Lab: (267) 426 5407
Education:
MD
Christian Albrechts University of Kiel, Germany, 2004.
Dr. med.
Christian Albrechts University of Kiel, Germany, 2004.
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Description of Research Expertise

T cell metabolism
Transplant Immunology
Regulatory T cells

Selected Publications

Angelin A, Gil-de-Gómez L, Dahiya S, Jiao J, Guo L, Levine MH, Wang Z, Quinn WJ 3rd, Kopinski PK, Wang L, Akimova T, Liu Y, Bhatti TR, Han R, Laskin BL, Baur JA, Blair IA, Wallace DC, Hancock WW, Beier UH: Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments. Cell Metabolism April 2017.

Angelin A, Gil-de-Gómez L, Dahiya S, Jiao J, Guo L, Levine MH, Wang Z, Quinn W, Kopinski PK, Wang L, Baur JA, Blair IA, Wallace DC, Hancock WW, Beier UH: Foxp3 increases oxidative phosphorylation and NAD oxidation, adapting regulatory T cells to low glucose high lactate environments. Euromit, Cologne, Germany 2017.

Jiao Jing, Han Rongxiang, Hancock Wayne W, Beier Ulf H: Proximity Ligation Assay to Quantify Foxp3 Acetylation in Regulatory T Cells. Methods in molecular biology (Clifton, N.J.) 1510: 287-293, 2017.

Laskin BL, Jiao J, Baluarte HJ, Amaral S, Furth SL, Akimova T, Hancock WW, Levine MH, Reese PP, Beier UH: The immunosuppressive effects of tacrolimus are short-lived: implications for T cell function testing and medication adherence. Transplantation Direct 2017.

Wang Liqing, Kumar Suresh, Dahiya Satinder, Wang Feng, Wu Jian, Newick Kheng, Han Rongxiang, Samanta Arabinda, Beier Ulf H, Akimova Tatiana, Bhatti Tricia R, Nicholson Benjamin, Kodrasov Mathew P, Agarwal Saket, Sterner David E, Gu Wei, Weinstock Joseph, Butt Tauseef R, Albelda Steven M, Hancock Wayne W: Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity. EBioMedicine 13: 99-112, Nov 2016.

Laskin BL, Singh HK, Beier UH, Moatz T, Furth SL, Bunin N, Witte D, Goebel J, Davies SM, Dandoy C, Jodele S, Nickeleit V: The Noninvasive Urinary Polyomavirus Haufen Test Predicts BK Virus Nephropathy in Children After Hematopoietic Cell Transplantation: A Pilot Study. Transplantation 100(10): e81-7, Oct 2016.

Levine MH, Wang Z, Xiao H, Jiao J, Wang L, Bhatti TR, Hancock WW, Beier UH: Targeting Sirtuin-1 prolongs murine renal allograft survival and function. Kidney Int 89(5): 1016-1026, May 2016.

Beier UH, Angelin A, Jiao J, Xiao H, Wang L, Dahiya S, Wells AD, Wallace DC, Hancock WW: Foxp3 controls oxidative phosphorylation in regulatory T cells. J Immunol 2016.

Dahiya S, Wang L, Beier UH, Angelin A, Han R, Wallace DC, Hancock WW: Deletion of a Class IIb Histone/protein Deacetylase (HDAC), HDAC10, Enhances FoxP3+ T-regulatory (Treg) Cell Suppressive Function, Gene Expression and Metabolism, and Promotes Allograft Survival. J Immunol abstract supplement, 2016.

Beier UH, Angelin A, Jiao J, Xiao H, Wang L, Dahiya S, Wells AD, Wallace DC, Hancock WW: Foxp3 controls oxidative phosphorylation in regulatory T cells. Am J Transplant abstract supplement, 2016.

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Last updated: 06/28/2017
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