Perelman School of Medicine/ Faculty Search/ Muredach P. Reilly

Muredach P. Reilly, MBBCH, MSCE

Associate Professor of Medicine

Department: Medicine

Graduate Group Affiliations

Pharmacology

Contact information

Translational Research Center
3400 Civic Center Blvd, Bldg 421
11th floor, Room 11-136
Philadelphia PA 19104
Philadelphia, PA 19104

Office: (215) 573-1214
Lab: (215) 573-0224

Email:
muredach@mail.med.upenn.edu

Publications

Search PubMed for articles

Links
Search PubMed for articles
Institute for Translational Medicine and Therapeutics
Cardiovascular Institute: For in-depth information on the group's latest research efforts, visit the Reilly Group at the Penn Cardiovascular Institute
Penn Health Profile

Education:
MBBCh (Medicine)
University College, Dublin, Ireland, 1988.
BS (Pharmacology)
University College Dublin, Ireland , 1990.
MSCE (Epidemiology and Biostatistics)
University of Pennsylvania, 2003.

Permanent link

Perelman School of Medicine > Faculty > Search

Description of Research Expertise

My group focuses on preclinical cell and rodent translational modeling, human cardiometabolic disease, as well as human genomics and epidemiology. I have a track record of translational, genomic and biomarker studies in heart and metabolic disease as well as in assembling multidisciplinary teams for execution of translational and genomic research. At this conference, I will present data on the genomics of coronary artery disease and myocardial infarction.

Selected Publications

Liu Y, Ferguson JF, Xue C, Silverman IM, Gregory BS, Reilly MP*, Li M*. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1458-9. doi: 10.1161/ATVBAHA.113.301632. No abstract available. PMID: 23766386: Evaluating the imapct of sequencing depth on transcriptome profiling of human adipose. PLoS One 33(7): 1458-9, July 2013 Notes: *equal contributing senior authors

Ferguson JF, Matthews GJ, Townsend RR, Raj DS, Kanetsky PA, Budoff M, Fischer MJ, Rosas SE, Kanthety R, Rahman M, Master SR, Qasim A, Li M, Mehta NN, Shen H, Mitchell BD, O’Connell JR, Alan R Shuldiner AR, Ho WK, Young R, Rasheed A, Danesh J, He J, Kusek JW, Ojo AO, John Flack J, Go AS, Gadegbeku CA, Wright JT, Saleheen D, Feldman HI, Rader DJ, Foulkes AS, Reilly MP; and the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. : Candidate Gene Association Study of Coronary Artery Calcification in Chronic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort Study J Amer Coll Cardiol (in press) May 2013 Notes: doi:pii: S0735-1097(13)02075-5. 10.1016/j.jacc.2013.01.103. [Epub ahead of print]

Olden M, Teumer A, Bochud M, Pattaro C, Köttgen A, Turner ST, Rettig R, Chen MH, Dehghan A, Bastardot F, Schmidt R, Vollenweider P, Schunkert H, Reilly MP, Fornage M, Launer LJ, Verwoert GC, Mitchell GF, Bis JC, O'Donnell CJ, Cheng CY, Sim X, Siscovick DS, Coresh J, Kao WH, Fox CS, O'Seaghdha CM; AortaGen, CARDIoGRAM, CHARGE Eye, CHARGE IMT, ICBP, NeuroCHARGE, and CKDGen Consortia. : Overlap Between Common Genetic Polymorphisms Underpinning Kidney Traits and Cardiovascular Disease Phenotypes: The CKDGen Consortium. Am J Kidney Dis. Mar 2013 Notes: doi:pii: S0272-6386(13)00029-2. 10.1053/j.ajkd.2012.12.024. [Epub ahead of print] PMID: 23474010.

Chan K, Patel RS, Newcombe P, Nelson CP, Qasim A, Epstein SE, Burnett S, Vaccarino VL, Zafari AM, Shah SH, Anderson JL, Carlquist JF, Hartiala J, Allayee H, Hinohara K, Lee BS, Erl A, Ellis KL, Goel A, Schaefer AS, El Mokhtari NE, Goldstein BA, Hlatky MA, Go AS, Shen GQ, Gong Y, Pepine C, Laxton RC, Whittaker JC, Tang WH, Johnson JA, Wang QK, Assimes TL, Nöthlings U, Farrall M, Watkins H, Richards AM, Cameron VA, Muendlein A, Drexel H, Koch W, Park JE, Kimura A, Shen WF, Simpson IA, Hazen SL, Horne BD, Hauser ER, Quyyumi AA, Reilly MP, Samani NJ, Ye S. : Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis. J Am Coll Cardiol. 61(9): 957-70, Mar 2013 Notes: doi: 10.1016/j.jacc.2012.10.051. Epub 2013 Jan 23. PMID: 23352782.

Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP, Assimes TL, Boerwinkle E, Hall AS, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson JR, König IR, Erdmann J, Samani NJ, Vasan RS, Schunkert H; on behalf of CARDIoGRAM. : Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk. Hypertension. Mar 2013 Notes: PMID: 23478099.

Ferguson F Jane, Patel N Parth, Shah Y Rhia, Mulvey K Claire, Gadi Ram, Nijjar S Prabhjot, Usman M Haris, Mehta N Nehal, Shah Rachana, Master R Stephen, Propert J Kathleen, Reilly P Muredach: Race and gender variation in response to evoked inflammation Journal of Translational Medicine. 11(63), March 2013 Notes: DOI: 10.1186/1479-5876-11-63 URL: http://www.translational-medicine.com/content/11/1/63.

Qasim AN, Rafeek H, Rasania SP, Churchill TW, Yang W, Ferrari VA, Jha S, Master SM, Mulvey CK, Terembula K, Dailing C, Budoff MJ, Kawut SM, Reilly MP. : Cardiovascular risk factors and mitral annular calcification in type 2 diabetes. Atherosclerosis. 226(2): 419-24, Feb 2013 Notes: doi: 10.1016/j.atherosclerosis.2012.11.011. Epub 2012 Dec 5. PMID: 23273961.

Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, Gaunt TR, Gho JM, Gieger C, Gong Y, Isaacs A, Kleber ME, Leach IM, McDonough CW, Meijs MF, Mellander O, Molony CM, Nolte IM, Padmanabhan S, Price TS, Rajagopalan R, Shaffer J, Shah S, Shen H, Soranzo N, van der Most PJ, Van Iperen EP, Van Setten JA, Vonk JM, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Boer JM, Boerwinkle E, Burkley B, Burt A, Chakravarti A, Chen W, Cooper-Dehoff RM, Curtis SP, Dreisbach A, Duggan D, Ehret GB, Fabsitz RR, Fornage M, Fox E, Furlong CE, Gansevoort RT, Hofker MH, Hovingh GK, Kirkland SA, Kottke-Marchant K, Kutlar A, Lacroix AZ, Langaee TY, Li YR, Lin H, Liu K, Maiwald S, Malik R; CARDIOGRAM, METASTROKE, Murugesan G, Newton-Cheh C, O'Connell JR, Onland-Moret NC, Ouwehand WH, Palmas W, Penninx BW, Pepine CJ, Pettinger M, Polak JF, Ramachandran VS, Ranchalis J, Redline S, Ridker PM, Rose LM, Scharnag H, Schork NJ, Shimbo D, Shuldiner AR, Srinivasan SR, Stolk RP, Taylor HA, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Winkelmann BR, Wyatt S, Young JH, Boehm BO, Caulfield MJ, Chasman DI, Davidson KW, Doevendans PA, Fitzgerald GA, Gums JG, Hakonarson H, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W; LifeLines Cohort Study, März W, Mitchell BD, Murray SS, Oldehinkel AJ, Rader DJ, Reilly MP, Reiner AP, Schadt EE, Silverstein RL, Snieder H, Stanton AV, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Johnson AD, Munroe PB, de Bakker PI, Zhu X, Levy D, Keating BJ, Asselbergs FW. : Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet. Feb 2013 Notes: Feb 7. [Epub ahead of print] PMID: 23303523.

Scialla JJ, Lau WL, Reilly MP, Isakova T, Yang HY, Crouthamel MH, Chavkin NW, Rahman M, Wahl P, Amaral AP, Hamano T, Master SR, Nessel L, Chai B, Xie D, Kallem RR, Chen J, Lash JP, Kusek JW, Budoff MJ, Giachelli CM, Wolf M. : Fibroblast growth factor 23 is not associated with and does not induce arterial calcification. Kidney Int. Feb 2013 Notes: doi: 10.1038/ki.2013.3. [Epub ahead of print] PMID: 23389416.

Foulkes AS, Matthews GJ, Das U, Ferguson JF, Lin R, Reilly MP. : Mixed Modeling of Meta-Analysis P-Values (MixMAP) Suggests Multiple Novel Gene Loci for Low Density Lipoprotein Cholesterol. PLoS One. 8(2): e54812, Feb 2013 Notes: doi: 10.1371/journal.pone.0054812. Epub 2013 Feb 6. PMID: 23405096.