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Kudakwashe Chikwava, MBChB

Kudakwashe Chikwava, MBChB

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Assistant Professor of Clinical Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
Department of Pathology
The Children’s Hospital of Philadelphia
Philadelphia, PA 19104
Office: (215) 590-1728
Fax: (215) 590-1736
Education:
MBChB (Bachelor of Medicine and Surgery)
University of Zimbabwe, 1997.
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Description of Clinical Expertise

Histiocytic disorders of childhood

Selected Publications

Whelan KA,Merves JF, Giroux J, Tanaka K, Guo A, Chandramouleeswaran PM, Benitez AJ, Dods K, Que J, Masterson JC, Fernando SD, Klein-Szanto AJ, Chikwava K, Ruchelli ED, Hamilton KE, Muir AB, Wang M, Furuta GT, Falk GW, Sperge JM, Nakagawa H : Autophagy mediates epithelial cytoprotection and redox homeostasis in Eosinophilic Esophagitis. Gut 2016 Notes: Accepted for publication.

Picarsic J, Egeler RM, Chikwava K, Patterson K, Jaffe R: Histologic patterns of thymic involvement in Langerhans cell proliferations: A clinicopathologic study and review of the literature. Pediatr. Dev. Pathol 18(2): 127-138, March-April 2015.

Cheng Y, Chikwava KR, Wu C, Zhang H, Bhagat A, Choi J, Tong W. : LNK (SH2B3) Suppresses B-precursor Acute Lymphoblastic Leukemia through IL-7 Receptor signaling. J Cli Investigation 2015 Notes: Submitted for review.

Maggadottir SM, Hill DA, Ruymann K, Brown-Whitehorn TF, Cianferoni A, Shuker M, Wang ML, Chikwava K, Verma R, Liacouras CA, Spergel JM.: Resolution of acute IgE-mediated allergy with development of eosinophilic esophagitis triggered by the same food. J Allergy Clin Immunol 133(5): 1487-1489, May 2014.

Boos MD, Chikwava KR, Dormans JP, Chauvin NA, Jen M: Lipofibromatosis: An Institutional and Literature Review of an Uncommon Entity. Pediatric Dermatology 31(3): 298-304, May 2014.

Doros LA, Rossi CT, Yang J, Field A, Williams GM, Messinger Y, Cajaiba MM, Perlman EJ, A Schultz K, Cathro HP, Legallo RD, Lafortune KA, Chikwava KR, Faria P, Geller JI, Dome JS, Mullen EA, Gratias EJ, Dehner LP, Hill DA.: DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma. Mod Pathol Page: [Epub ahead of print] Jan 2014.

Mario Noti, Elia D Tait Wojno, Brian S Kim, Mark C Siracusa, Paul R Giacomin, Meera G Nair, Alain J Benitez, Kathryn R Ruymann, Amanda B Muir, David A Hill, Kudakwashe R Chikwava, Amin E Moghaddam, Quentin J Sattentau, Aneesh Alex, Chao Zhou, Jennifer H Yearley, Paul Menard-Katcher, Masato Kubo, Kazushige Obata-Ninomiya, Hajime Karasuyama, Michael R Comeau, Terri Brown-Whitehorn, Rene de Waal Malefyt, Patrick M Sleiman, Hakon Hakonarson: Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis. Nature Medicine doi:10.1038/nm.3281, July 2013.

Bersenev A, Wu C, Balcerek J, Jing J, Kundu M, Chikwava KR, Tong W: Lnk Constrains Myeloproliferative Diseases in Mice. Journal of Clinical Investigation 120(6): 2058-2069, Jun 2010.

Lohr NJ, Molleston JP, Strauss KA, Torres-Martinez W, Sherman EA, Squires RH, Rider NL, Chikwava KR, Cummings OW, Morton DH, Puffenberger EG: Human ITCH E3 ubiquitin ligase deficiency causes syndromic multisystem autoimmune disease. Am J Hum Genet 86(3): 447-53, March 2010.

Chikwava KR, Hunt JL, Mantha GS, Murphy JE, Jaffe R: Analysis of loss of heterozygosity in single-system and multisystem Langerhans' cell histiocytosis. Pediatric and developmental pathology 10(1): 18-24, Jan-Feb 2007.

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Last updated: 01/28/2016
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