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Chee M Ng, PharmD, PhD, FCP

Chee M Ng, PharmD, PhD, FCP

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Research Assistant Professor of Pediatrics
Department: Pediatrics

Contact information
Clinical Pharmacology and Therapeutics
Children Hospital of Philadelphia
Room 4010 CTRB Building
3501 Civic Center Blvd
Philaldelphia, PA 19104
Office: 267-4262826
Education:
B.S. (Pharmacy)
State University of New York at Buffalo, 1991.
PharmD (High Honor)
University of Illinois at Chicago, 1995.
PhD (Pharmaceutical Science)
University of North Carolina at Chapel Hill, 2002.
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Selected Publications

Ng CM: Novel hybrid artificial neural network-nonlinear mixed-effect modeling approach for population data analysis in model-based drug development. Population Approach Group in European (PAGE) Annual Meeting 2012.

Choo EF, Ng CM, Berry L, Belvin M, Koh NL, Merchant M, Salphati L: Pharmacokinetic-pharmacodynamic modeling of combination efficacy effect from administration of a MEK inhibitor, GDC-0972 and PI3K inhibitor, GDC-0941 in A2058 xenografts. Accepted for publication by Cancer Chemother Pharmacol 2012.

Shellhaas R, Ng CM, Barks JD, Bhatt-Metha V. : Population pharmacokinetics of Phenobarbital in infants with neonatal encephalopathy treated with therapeutic hypothermia. Ped Crit Care Med (in press) 2012.

Hsu YH, Ferl GZ, Ng CM: GPU-accelerated Nonparametric Kinetic Analysis of DCE-MRI Data from Glioblastoma Patients Treated with Bevacizumab. Accepted by Magnetic Resonance Imaging for Publication 2012.

Ng CM: Novel GPU-based parallelized Quasi-random parametric expectation-maximization (QRPEM) estimation method for population data analysis. Population Approach Group in European (PAGE) Annual Meeting 2011.

Ng CM, Patnaik A, Beeram M, Lin CC, Bauer RJ, Takimoto CH: Mechanism-based pharmacokinetic/pharmacodynamic model for troxacitabine-induced neutropenia in cancer patients. Cancer Chemother Pharmacol 67(5): 985-94, 2011.

Ng, CM: Novel GPU parallelization of Monte-Carlo Parametric Expectation Maximization estimation algorithm for population data analysis. American College of Pharmacometrician (ACOP) Annual Meeting 2011.

Takimoto CH, Ng CM, Pulchalski T: Pharmacokinetics and Pharmacodynamics. Cancer: Principles and Practices of Oncology. De Vita V, Lawrence T, Rosenberg S (eds.). Lippincott Williams & Wilkins, Philadelphia PA, 2011.

Ng CM, Bai S, Takimoto CH, Tolcher AW: Mechanism-based receptor-binding model to describe the population pharmacokinetic and pharmacodynamic of an anti-α5β1 integrin monoclonal antibody (voloxicimab) in cancer patients. Cancer Chemother Pharmacol 65(2): 207-17, 2010.

Williams JH, Ng CM, Creig J, Wilson JM, Barrett JS: Modeling and simulation of erythropoietin expression following AAV-mediated gene transfer. J Clin Pharmacol 50: 1090, 2010.

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Last updated: 09/21/2012
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