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Perelman School of Medicine at the University of Pennsylvania Advanced Search

Reshma Munbodh, Ph.D.

Reshma Munbodh, Ph.D.

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Assistant Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Department: Radiation Oncology

Contact information
Department of Radiation Oncology
The Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-349-5146
Education:
B.Eng. (Computer Science & Electronics, First-Class Honours)
University of Edinburgh, 1996.
M.Sc. (Electrical Engineering)
Yale University, 1999.
M.Phil. (Electrical Engineering)
Yale University, 2000.
Ph.D. (Electrical Engineering)
Yale University, 2004.
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Description of Clinical Expertise

IMRT and 3D CRT treatment planning for various sites including the head and neck, prostate, lungs, gastric bed, breast and spine. Brachytherapy with LDR and HDR therapies to prostate, ovarian, gynecological, lung, breast and gastrointestinal sites, brachytherapy QA. Radiation safety experience in patient briefings, surveys, and shielding design. Monthly and annual QA on Varian therapy machines. Beam data acquisition and treatment planning system commissioning for the treatment of small fields in stereotactic radiation therapy. 4D CT image acquisition and evaluation. Proton commissioning and QA.

Description of Other Expertise

Platforms: Unix, Linux, Windows.
Primary programming languages: C, C++, VTK, ITK, MATLAB
Other languages and databases: Java, Standard ML, Haskell, SQL Windows, and several other application packages.

Description of Research Expertise

Medical image analysis, medical imaging physics, rigid and deformable image registration, 2D-3D image registration, image segmentation, statistical estimation theory, optimization techniques, pattern recognition and machine learning.

I am interested in the development of new image analysis and computational techniques to allow more accurate treatment and a better understanding of cancer. My research is focused in three areas: 1) the development of image registration algorithms for IGRT for prostate cancer and for brain tumors, 2) the study of toxicity after radiation therapy and the development of new normal tissue complication probability models that take into account the spatial and morphological characteristics of complex radiation dose distributions as well as dose volume characteristics, 3) the study of brain gliomas using quantitative imaging markers to better understand how gliomas progress with time.

Selected Publications

Munbodh R, Jackson A: Quantifying cell migration distance as a contributing factor to the development of rectal toxicity after prostate radiotherapy. Med. Phys. 41(2): 021716-1-12, Feb 2014.

Munbodh R, Moseley DJ: 2D-3D registration for brain radiation therapy using a 3D CBCT and a single limited field-of-view 2D kV radiograph. J. Phys.: Conf. Ser. 489(012037), Mar 2014.

Turner JD, Joshi BS, Panday A, Munbodh R, Zaveri HP: A comparison of Euclidean and brain surface cortico-cortical distance measures. Proceedings of the 6th International IEEE/EMBS Conference on Neural Engineering (NER) 2013.

Jin P, Munbodh R, Lin A, Zhu T: Transmission verification using the on-board EPID. AAPM 55th Annual Meeting, Indianapolis, Indiana July 2013 Notes: Oral presentation.

Yin L, Kremmel E, Alonso-Basanta M, Munbodh, R: Dosimetric indicators of radiation-induced toxicity in meningioma patients. AAPM 55th Annual Meeting, Indianapolis, Indiana July 2013.

Teo BK, Saboury B, Munbodh R, Scheuermann J, Torigian DA, Zaidi H, Alavi A : The effect of breathing irregularities on quantitative accuracy of respiratory gated PET/CT. Med. Phys. 39(12): 7390-7397, Dec 2012.

Munbodh R, Young RJ, Tagare H, Nguyen NT, Friguglietti L, Beal K: Quantification of tumor growth kinetics in patients showing progression from low grade to high grade gliomas. ASTRO 54th Annual Meeting, Boston, MA. Int J Radiat Oncol, Biol, Phys. Oct 2012.

Munbodh R, Tagare H, Chen Z, Jaffray DA, Moseley DJ, Knisely, JPS, Duncan JS: Image registration for prostate radiation therapy based on a statistical model of transmission images. Med. Phys. 36(10): 4555-4568, Oct 2009.

Munbodh R, Jackson A, Bauer J, Schmidtlein CR, Zelefsky MJ: Dosimetric and spatial indicators of late rectal toxicity after high-dose intensity modulated radiation therapy for prostate cancer. Med. Phys. 35(5): 2137-2150, May 2008.

Munbodh R, Chen Z, Jaffray DA, Moseley DJ, Knisely JPS, Duncan JS: Automated 2D-3D registration of MV portal images and kV cone-beam CT data using line-segment enhancement. Med. Phys. 35(5): 4352-4361, Oct 2008.

Munbodh R, Chen Z, Jaffray DA, Moseley DJ, Knisely JPS, Duncan JS: A frequency-based approach to locate common structure for 2D-3D intensity-based registration of setup images in prostate radiotherapy. Med. Phys. 34(7): 3005-3017, Jul 2007.

Munbodh R, Jaffray DA, Moseley DJ, Chen Z, Knisely JPS, Cathier P, Duncan JS: Automated 2D-3D registration of a radiograph and a Cone-Beam CT using line-segment enhancement. Med. Phys. 33(5): 1398-1411, May 2006.

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Last updated: 03/26/2014
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