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Frederic Bibollet-Ruche, Ph.D.

Frederic Bibollet-Ruche, Ph.D.

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Research Assistant Professor of Medicine
Department: Medicine

Contact information
University of Pennsylvania
423A Johnson Pavilion
3610 Hamilton Walk
Philadelphia, PA 19104
Office: 215-573-6462
M.S. (Biochemistry)
University of Paris VI, Paris, France, 1989.
Ph.D. (Biological Sciences and Molecular Biology)
University of Sciences and Techniques of languedoc, Montpellier II, France, 1996.
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Selected Publications

Letko Michael, Silvestri Guido, Hahn Beatrice H, Bibollet-Ruche Frederick, Gokcumen Omer, Simon Viviana, Ooms Marcel: Vif proteins from diverse primate lentiviral lineages use the same binding site in APOBEC3G. Journal of virology 87(21): 11861-71, Nov 2013.

Kluge Silvia F, Sauter Daniel, Vogl Michael, Peeters Martine, Li Yingying, Bibollet-Ruche Frederic, Hahn Beatrice H, Kirchhoff Frank: The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function. Retrovirology 10: 10-32, March 2013.

Sauter Daniel, Unterweger Daniel, Vogl Michael, Usmani Shariq M, Heigele Anke, Kluge Silvia F, Hermkes Elisabeth, Moll Markus, Barker Edward, Peeters Martine, Learn Gerald H, Bibollet-Ruche Frederic, Fritz Joëlle V, Fackler Oliver T, Hahn Beatrice H, Kirchhoff Frank: Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein. PLoS pathogens 8(12): e1003093, Dec 2012.

Li Yingying, Ndjango Jean-Bosco, Learn Gerald H, Ramirez Miguel A, Keele Brandon F, Bibollet-Ruche Frederic, Liu Weimin, Easlick Juliet L, Decker Julie M, Rudicell Rebecca S, Inogwabini Bila-Isia, Ahuka-Mundeke Steve, Leendertz Fabian H, Reynolds Vernon, Muller Martin N, Chancellor Rebecca L, Rundus Aaron S, Simmons Nicole, Worobey Michael, Shaw George M, Peeters Martine, Sharp Paul M, Hahn Beatrice H: Eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir. Journal of virology 86(19): 10776-91, Oct 2012.

Götz Nicola, Sauter Daniel, Usmani Shariq M, Fritz Joëlle V, Goffinet Christine, Heigele Anke, Geyer Matthias, Bibollet-Ruche Frederic, Learn Gerald H, Fackler Oliver T, Hahn Beatrice H, Kirchhoff Frank: Reacquisition of Nef-Mediated Tetherin Antagonism in a Single In Vivo Passage of HIV-1 through Its Original Chimpanzee Host. Cell host & microbe 12(3): 373-80, Sep 2012.

Kong Rui, Li Hui, Georgiev Ivelin, Changela Anita, Bibollet-Ruche Frederic, Decker Julie M, Rowland-Jones Sarah L, Jaye Assan, Guan Yongjun, Lewis George K, Langedijk Johannes P M, Hahn Beatrice H, Kwong Peter D, Robinson James E, Shaw George M: Epitope mapping of broadly neutralizing human HIV-2 monoclonal antibodies. Journal of virology Aug 2012.

Bibollet-Ruche Frederic, Heigele Anke, Keele Brandon F, Easlick Juliet L, Decker Julie M, Takehisa Jun, Learn Gerald, Sharp Paul M, Hahn Beatrice H, Kirchhoff Frank: Efficient SIVcpz replication in human lymphoid tissue requires viral matrix protein adaptation. The Journal of clinical investigation 122(5): 1644-52, May 2012.

Bello Nana F, Dussupt Vincent, Sette Paola, Rudd Victoria, Nagashima Kunio, Bibollet-Ruche Frederic, Chen Chaoping, Montelaro Ronald C, Hahn Beatrice H, Bouamr Fadila: Budding of retroviruses utilizing divergent L domains requires nucleocapsid. Journal of virology 86(8): 4182-93, Apr 2012.

de Silva Thushan I, Aasa-Chapman Marlén, Cotten Matthew, Hué Stéphane, Robinson James, Bibollet-Ruche Frederic, Sarge-Njie Ramu, Berry Neil, Jaye Assan, Aaby Peter, Whittle Hilton, Rowland-Jones Sarah, Weiss Robin: Potent autologous and heterologous neutralizing antibody responses occur in HIV-2 infection across a broad range of infection outcomes. Journal of virology 86(2): 930-46, Jan 2012.

Kong Rui, Li Hui, Bibollet-Ruche Frederic, Decker Julie M, Zheng Natalie N, Gottlieb Geoffrey S, Kiviat Nancy B, Sow Papa Salif, Georgiev Ivelin, Hahn Beatrice H, Kwong Peter D, Robinson James E, Shaw George M: Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection. Journal of virology 86(2): 947-60, Jan 2012.

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Last updated: 12/05/2013
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