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Alejandro Carabe-Fernandez, Ph.D.

Alejandro Carabe-Fernandez, Ph.D.

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Assistant Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Department: Radiation Oncology

Contact information
Hospital of the University of Pennsylvania
Department of Radiation Oncology
TRC 4 West,
3400 Civic Center Boulevard
Philadelphia, PA 19104
Phiadelphia, PA 19104
Office: (215) 614-1605
Education:
MPhys (Physics with Medical Technology)
University of Hull, 2000.
MSc (Medical Physics)
University of Glasgow, 2002.
Ph.D. (Radiobiology)
Imperial College, 2008.
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Description of Clinical Expertise

Proton and convencional radiotherapy

Description of Research Expertise

Clinical and theoretical radiobiology
High-LET radiobiology and radiotherapy
Radiobiological Optimization
TCP/NTCP specific for high-LET radiations
Repair kinetics modeling

Selected Publications

Carabe A, Moteabbed M, Depauw N, Schuemann J, Paganetti H.: Range uncertainty in proton therapy due to variable biological effectiveness. Phys Med Biol. IoP, 57(5): 1159-72, March 2012.

Carabe-Fernandez A, Dale RG, Jones B: Repair kinetic considerations in high-LET particle beam radiotherapy. Br J Radiol 2011 Notes: in press.

Jones B, Underwood TS, Carabe-Fernandez A, Timlin C, Dale RG.: Fast neutron relative biological effects and implications for charged particle therapy. British Journal of Radiology 84(1): S11-S18, 2011.

Carabe-Fernandez A, Dale RG, Hopewell JW, Jones B, Paganetti H: Fractionation effects in particle radiotherapy: implications for hypo-ractionation regimes. Phys Med Biol 55(19): 5685-700, 2010.

Jones B, Dale RG, Carabe-Fernandez A: Charged particle therapy for cancer: The inheritance of the Cavendish scientists? Appl Radiat Isot 67(3): 371-7, 2009.

Dale RG, Jones B, Carabe-Fernandez A: Why more needs to be known about RBE effect in modern radiotherapy. Appl Radiat Isot 67(3): 387-92, 2009.

Jones B, Carabe-Fernandez A, Dale RG: The oxygen effect. Radiobiological Modeling in Radiation Oncology. Dale RG and Jones B (eds.). The British Institute of Radiology, Page: 138-157, 2007.

Carabe-Fernandez A, Dale RG, Jones B: The incorporation of the concept of minimum RBE (RBEmin) into the linear-quadratic model and the potential for improved radiobiological analysis of high-LET treatments. Int J Radiat Biol 83(1): 27-39, 2007.

Jones B, Dale RG, Carabe-Fernandez A: High-LET radiotherapy. Radiobiological Modeling in Radiation Oncology. Dale RG and Jones B (eds.). The British Institute of Radiology, Page: 265-275, 2007.

Jones B, Carabe-Fernandez A, Dale RG: Calculation of high-LET radiotherapy dose required for compensation of overall treatment time extensions. Br J Radiol 79(939): 254-7, 2006.

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Last updated: 08/28/2012
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