Ildiko Csiki, M.D., Ph.D.
Ildiko Csiki, M.D., Ph.D.
Assistant Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Department: Radiation Oncology
Contact information
Department of Radiation Oncology
Smilow Center for Translational Research, 8-133
Perelman School of Medicine
University of Pennsylvania
3400 Civic Center Blvd., Bldg 421
Philadelphia, PA 19104
Smilow Center for Translational Research, 8-133
Perelman School of Medicine
University of Pennsylvania
3400 Civic Center Blvd., Bldg 421
Philadelphia, PA 19104
Office: 215-662-6567
Fax: 215-349-8975
Lab: csikii@uphs.upenn.edu
Fax: 215-349-8975
Lab: csikii@uphs.upenn.edu
Publications
Education:
B.A.
University of Arkansas, 1999.
B.S.
University of Arkansas, 1999.
Ph.D.
Vanderbilt University, 2004.
M.D.
Vanderbilt University School of Medicine, 2007.
Permanent linkB.A.
University of Arkansas, 1999.
B.S.
University of Arkansas, 1999.
Ph.D.
Vanderbilt University, 2004.
M.D.
Vanderbilt University School of Medicine, 2007.
Description of Research Expertise
Clinical interests: Non-Small Cell Lung Cancer; Small Cell Lung Cancer; Radiosensitization, Low-Dose Rate Radiotherapy, Biologic Targeted Therapies for Lung Cancer; Stereotactic Body Radiation Therapy;Research interests:
My laboratory's objective is characterization of the sonic hedgehog pathway in lung tumorigenesis and the role of Gli1 overexpression in lung tumor development using a Gli1 conditional knock-in mouse model. In addition we are interested in characterizing the metabolomic profile of lung tumor and non-tumor stem cells and identify key pathways for lung cancer cells with stem cell features for better therapeutic targeting.
Selected Publications
Malvi Savani, Yan Guo, David P. Carbone, and Ildiko Csiki : Sonic hedgehog pathway expression in non-small cell lung cancer. Ther Adv Med Oncol. 4(5): 225-33, Sep 2012.Csiki I, Hwang M, Kirby W, Crass J, Ding GX, Lu B: Deep inspiration breath hold kV CBCT-Guided SBRT using the Varian Trilogy System in a patient with stage I lung cancer. in "Image-Guided Radiation Therapy." Image-Guided Radiation Therapy 2011 Notes: ed. 1 by Mundt.
Csiki I., Desai, F., Martyn, P.C., Gius, D., Carbone, D.: The Signaling Pathway Modulates Stem Cells in Non-small Cell Lung Cancer. ASTRO Bench to Bedside and Back, 3B meeting, Atlanta, GA 2011 Notes: Poster presentation.
Novitskiy S, Csiki I, Huang Y, Sandler AB, Johnson DH, Carbone DP, Dikov MM: Anti-VEGF treatment in combination with chemotherapy delays hematopoietic recovery due to decreased proliferation of bone marrow hematopietic progenitor cells. Journal of Thoracic Oncology 5(9): 1410-5, Sep 2010.
Spratt DE, Diaz R, McElmurray J, Csiki I, Duggan D, Lu B, Delbeke D: Impact of FDG PET/CT on delineation of the gross tumor volume for radiation planning in non-small-cell lung cancer. Clin Nucl Med 35(4): 237-43, Apr 2010.
Csiki, I., Desai, F., Martyn, P.C., Giu, D., Carbone, D.: Modulation of stem cells in non-small cell lung cancer using IPI-926 to target the Sonic Hedghog Signaling Pathway. ASTRO Annual Meeting, San Diego, CA 2010 Notes: Oral presentation.
Csiki I, Novitskiy S, Huang Y, Sandler AB, Johnson DH, Carbone DP, Dikov MM: Anti-VEGF treatment in combination with chemotherapy delays hematopoietic recovery due to decreased proliferation of bone marrow hematopoietic progenitor cells. 13th IASLC meeting, San Francisco, CA Aug 2009 Notes: Poster presentation.
Sasi N, Hwang M, Jaboin J, Csiki I, Lu B: Regulated Cell Death Pathways: New Twists in Modulation of BCL2 Family Function. Molecular Cancer Therapeutics. Molecular Cancer Therapeutics 8(6): 1421-9, Jun 2009.
Csiki I, Morrow J, Carbone DP, Johnson DH, Lu B: Use of biomaker response to celecoxib to predict radiation induced lung and esophageal toxicity: A strategy to individualize thoracic radiation therapy. Vanderbilt University Annual Research Forum, Nashville, TN Apr 2009 Notes: Poster presentation.
Csiki I, Novitskiy S, Dikov MM, Sandler AB, Johnson DH, Carbone DP: Mechanism of vascular endothelial growth factor (VEGF) blockade induced myelosupression in lung cancer patients treated with anti-VEGF therapy. Vanderbilt University Annual Research Forum, Nashville, TN Apr 2009 Notes: Oral Presentation.